Protein Alignment Cdc37 and cdc-37

DIOPT Version :10

• Sequence 1: NP_477006.1
• Gene: Cdc37 / 38232
• FlyBaseID: FBgn0011573
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_001367479.1
• Gene: cdc-37 / 173449
• WormBaseID: WBGene00021097
• Length: 403
• Species: Caenorhabditis elegans
• Alignment Length: 369
• Identity: 149/369 - (40%)
• Similarity: 234/369 - (63%)
• Gaps: 12/369 - (3%)

  Fly     2 VDYSKWKNIEISDDEDDTHPNIDTPSLFRWRHQARVERMAEMDHEKDELKKKRQSYQARLMDVKE 66
            :||||||:||:||||||||||||||||||||||||:|||||...|::::.|::.:...::.::::
 Worm    36 IDYSKWKDIEVSDDEDDTHPNIDTPSLFRWRHQARLERMAEKKMEQEKIDKEKGTTSKKMEELEK 100

  Fly    67 RISKKD-GDEEALKKELEKIEAEGKELDRIESEMIKKEKKTPWNVDTISKPGFEKTVINKKAGRK 130
            :::..| .|:..::|::::::|:.:...:.|:|:.:||:..|||||||....|..:.|||...:|
 Worm   101 KLAAADVTDKSDIQKQIDEVKAQEEAWRKKEAELEEKERLEPWNVDTIGHEAFSTSRINKITEKK 165

  Fly   131 PDENLSEEEREQRMKQFVKENEKLCQQYGMLRK-YDDSKRFLQEHLHLVGEETANYLVIWSINLE 194
            |....::||....|..|.:.:|.|.::..:|:. ...::.||.||.|:..|.|||:|.|.::|..
 Worm   166 PQAPKTDEEDTHAMSTFFETHESLLEKMAVLKNGAKSTELFLAEHPHMASEYTANWLTIEALNAA 230

  Fly   195 MEEKHELMAHVAHQCICMQYILELAKQLD-VDPRACV-SSFFSKIQHCHPEYRAQFDSEIEGFKG 257
            ::...|.|..:|.|||.:||:|||:|.|: |.....| ..||.|.:...|.|...:..|::.|:.
 Worm   231 IDFNEEKMKTMAEQCIIIQYLLELSKSLNAVATNTTVQKQFFKKFEAAEPVYMKHYQDEVKAFED 295

  Fly   258 RIQKRAQEKIQEAIAQAEEEERKERL--GPGGLDPADVFESLPDELKACFESRDVELLQKTIAAM 320
            |::.|||.|...|:.:||.||:.||:  .|||:||.:|||.||:|::.|||:.|:|.|:.....|
 Worm   296 RLRTRAQTKRDAAMEEAEAEEKAERMKSAPGGIDPQEVFEQLPEEMRKCFEAHDIEALKGVAQKM 360

  Fly   321 PVDVAKLHMKRCVDSGLWVPNAADLEGDKKEEDDSDDVAGGEEK 364
            ..:|.|.|..||:.||||||..||      ::||.::.|..||:
 Worm   361 DEEVFKYHFDRCIASGLWVPGKAD------DDDDDEEAAPAEEE 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc37	NP_477006.1	CDC37_N	1..121	CDD:198139	55/119 (46%)
		CDC37_M	130..266	CDD:215010	47/138 (34%)
		CDC37_C	283..372	CDD:215009	36/84 (43%)
cdc-37	NP_001367479.1	CDC37_N	35..156	CDD:198139	55/119 (46%)
		CDC37_M	161..306	CDD:215010	48/144 (33%)
		CDC37_C	325..>382	CDD:215009	29/56 (52%)