DRSC/TRiP Functional Genomics Resources

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Protein Alignment alpha-Spec and C07A9.5

DIOPT Version :9

Sequence 1:NP_001261286.1 Gene:alpha-Spec / 38231 FlyBaseID:FBgn0250789 Length:2457 Species:Drosophila melanogaster
Sequence 2:NP_499140.1 Gene:C07A9.5 / 182355 WormBaseID:WBGene00007401 Length:358 Species:Caenorhabditis elegans


Alignment Length:344 Identity:76/344 - (22%)
Similarity:154/344 - (44%) Gaps:84/344 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly  2127 FKALAALDQKIKSFNVGPNPYTWFTMEALEETWRNLQKIIEERDGELAKEAKRQEENDKLRKEFA 2191
            ||.||:                  .||.|::|..:..:|:   |||::    |..:|:|:.::.|
 Worm    84 FKTLAS------------------RMERLDQTISDRIRIV---DGEIS----RHSDNEKICEQAA 123

  Fly  2192 --------------KHANLFHQWLTETRYYMLGYNRQGTSMMEGSGSLEQQLEALRVKATEVRAR 2242
                          |...:.|                       |..||.|.::|.....:|:..
 Worm   124 CTLKTCDNVIVDVKKELEMLH-----------------------SLRLEDQKKSLMNLIAKVQKS 165

  Fly  2243 RVDLKKIEELGALLEEHLILDNRYTEHSTVGLAQQWDQLDQLSMRMQHNLEQQIQARNHSGVSED 2307
            .: ::.:|:..:|:|...|.||.::..:..|:..:..|..:|...|..::||.|..|||:||:|.
 Worm   166 GM-IQDLEKWRSLMESRYIFDNTFSSATPHGVLVEMCQCLELMSSMLRSVEQSIADRNHNGVTEK 229

  Fly  2308 SLKEFSMMFKHFDKDKSGKLNHQEFKSCLRALGYDLPMVEEGQPDPEFEAILDVVDPNRDGYVSL 2372
            .|.||.:.|.:||::|:|.|:::.|:.||::.||:..:      :...:..:.::||:.   ...
 Worm   230 QLHEFKLAFDYFDQEKNGWLDYEHFELCLKSQGYNFSV------ESTLKETMSLLDPST---YEK 285

  Fly  2373 QEYIAFMISKETENV-QSYEEIENAFRAITAADRPYVTKEELYCNLTKDMADYCVQRMKPFSEPR 2436
            .:|:.:|:..||.|: ..:..||:|.:.:.|        .::..::::..|::.:.::...:|..
 Worm   286 HDYMRYMVKHETTNILDDHSAIEDALKNLDA--------RKISDSMSRKEAEFFMSKIAKKAETS 342

  Fly  2437 SGQPIKDALDYIDFTRTLF 2455
            |.|.   .|:|.||..:.:
 Worm   343 SDQV---CLEYKDFVNSFY 358

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alpha-SpecNP_001261286.1 SH3_Alpha_Spectrin 974..1026 CDD:212742
SPEC 1074..1287 CDD:238103
SPEC 1182..1425 CDD:238103
SPEC 1426..1638 CDD:238103
SPEC 1533..1744 CDD:238103
SPEC 1646..1850 CDD:238103
SPEC 1852..2062 CDD:238103
SPEC 1958..2176 CDD:238103 12/48 (25%)
SPEC 2072..2296 CDD:238103 36/182 (20%)
EFh 2311..2379 CDD:238008 16/67 (24%)
EFhand_Ca_insen 2386..2456 CDD:400872 13/71 (18%)
SPEC 48..258 CDD:238103
SPEC 154..364 CDD:238103
SPEC 261..470 CDD:238103
SPEC 471..680 CDD:238103
SPEC 682..893 CDD:238103
Spectrin 893..>961 CDD:395348
C07A9.5NP_499140.1 PTZ00183 224..>327 CDD:185503 28/119 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0040
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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