Protein Alignment mRpL46 and MRPL46

DIOPT Version :10

• Sequence 1: NP_647661.1
• Gene: mRpL46 / 38230
• FlyBaseID: FBgn0035272
• Length: 258
• Species: Drosophila melanogaster
• Sequence 2: NP_071446.2
• Gene: MRPL46 / 26589
• HGNCID: 1192
• Length: 279
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 95/256 - (37%)
• Similarity: 148/256 - (57%)
• Gaps: 12/256 - (4%)

  Fly     8 VGARELSRAQSSTASAEKWDLYAGVLVERLPVVSKSLNPLEKQFQDLLWRVEYENSLKSDHELKH 72
            :.:|.|:.|.:.:::...|.|...:.::|.|||||.|.||:::...||.::|.|.||.|||||:
Human    27 LSSRSLALAAAPSSNGSPWRLLGALCLQRPPVVSKPLTPLQEEMASLLQQIEIERSLYSDHELR- 90

  Fly    73 EREIVQAELIKQGKIQVDLEDAGSKQ---TAQDLKDAYVEELKKFQLGSRTTPDDQANRTTSTDR 134
                ...|..:..|.:.||.|...:|   .||||:|.:.::..:|:||:|.|..|:.|..||.:|
Human    91 ----ALDENQRLAKKKADLHDEEDEQDILLAQDLEDMWEQKFLQFKLGARITEADEKNDRTSLNR 151

  Fly   135 CLDDTLYLLVQQKLGQQEHLILPQGKREEGESMRQTAERVLRESCGQELQVLFYGNAPVGFHKYK 199
            .||..|.|||::|.|.|:..||||.:.:.||::|.||||.|.......::..|.||||.|.:.:|
Human   152 KLDRNLVLLVREKFGDQDVWILPQAEWQPGETLRGTAERTLATLSENNMEAKFLGNAPCGHYTFK 216

  Fly   200 YPRNQRTET-VGAKVFFYRASLRSGQVPE--NLTKFEWLPKEALNEKLTNTAYAQSVKKFL 257
            :|:..|||: :||||||::|.|.:|...:  |.....|:.|:.|.:.| ...|...|::|:
Human   217 FPQAMRTESNLGAKVFFFKALLLTGDFSQAGNKGHHVWVTKDELGDYL-KPKYLAQVRRFV 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mRpL46	NP_647661.1	MRP-L46	26..124	CDD:432074	38/100 (38%)
		NUDIX_MRP_L46	118..256	CDD:467546	55/140 (39%)
MRPL46	NP_071446.2	MRP-L46	45..141	CDD:432074	38/100 (38%)
		NUDIX_MRP_L46	136..275	CDD:467546	55/139 (40%)