Protein Alignment Pol31 and cdc1

DIOPT Version :9

• Sequence 1: NP_647659.1
• Gene: Pol31 / 38228
• FlyBaseID: FBgn0027903
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_594406.1
• Gene: cdc1 / 2542083
• PomBaseID: SPAC27E2.05
• Length: 462
• Species: Schizosaccharomyces pombe
• Alignment Length: 466
• Identity: 149/466 - (31%)
• Similarity: 234/466 - (50%)
• Gaps: 60/466 - (12%)

  Fly     6 ETKYENLSSIFRLKGHDYQKQFFHLYAHRLAEMTRLLTPLAQKKWGNKEPIKKLCELRGEQDVHC 70
            |||...||    |....|.:|:..:|..||..:...:|..|.|||.:|:.::::.:::.::|  |
pombe    12 ETKRLELS----LSQQTYSQQYASIYFARLTALRPRITEAASKKWPDKQRLERVLDVKSDED--C 70

  Fly    71 ILIGTIFKHQAHKPSILRDISEENQLAPQPPRQNYSDPED------KIVLEDELQRVRLQGK-LN 128
            .::.|.:...|.||:::.|:::.:.:........|..|||      :..|||:..|:...|. |.
pombe    71 WVVATAYMTTALKPNVMNDVTQLHTIVTTTEESPYVSPEDAASGDIEYALEDDYGRIDCSGSFLY 135

  Fly   129 GQLLATGVVCAALGGTDSDGFFNVEDI----LFYESGPQ-------KPLAPIKRSRLLVLASGLD 182
            ...:.||||.|.||..|..|.|.|.|:    :|..|.|.       :|......|.|.:...|::
pombe   136 DAGVVTGVVLAVLGHEDEQGRFVVVDVCFPGIFSHSIPMTTDESQAQPEYIAAVSGLGLSNDGIE 200

  Fly   183 QLQAHKFVEALNLFQYWLAGSLG--NNKEAGSMVRLIVAGN------SVRASAMAHVP--TLQVA 237
            .:|.|:.|:       :|.|:|.  ::....|:.|||:.||      .:..||.|.||  ..:|.
pombe   201 GIQVHQLVD-------FLRGTLPHVSSFSPSSIKRLIILGNCLAPSIEIADSASASVPIGKKKVK 258

  Fly   238 R----TQA-NANDTVQAVSQLDQWFASWARSLPVDIMPGPYDPANFMLPQQPFHKCMFPQAAQL- 296
            |    |.| |.|.|.    |||.:......|:.|.:||||||.::.:|||||.|..:..::...
pombe   259 RYGYDTSAYNPNPTF----QLDNFLDQVCSSIDVTLMPGPYDYSSTILPQQPLHPALLTKSKVWL 319

  Fly   297 -ATFQAVTNPYSCRLDEALVVGTSGQNVSDLLRSTSLDSALEALRCTLTWGHVAPTAPDTLACYP 360
             ::.|.||||....|....|:.|||||::||.:.....|:|:.:..||.|.|:.||:||||.|||
pombe   320 GSSLQTVTNPTWLSLGNHFVLATSGQNINDLRKYHPKKSSLQCMENTLLWNHITPTSPDTLWCYP 384

  Fly   361 YIESDPFILRECPHVYYAGNCESFA--TELHEGSEGKRTRLVCVPSFSKTQSVAVVDLDTLDCRM 423
            :.:.|.|::.|.|.:|..||...|.  |.::||:   |.:||.||.|.||..:.::::.||:..:
pombe   385 FTDKDTFVMEEMPDLYLCGNQPKFGCKTVINEGN---RIQLVSVPEFRKTGVLVLINMHTLNVEI 446

  Fly   424 VNF---SVDAE 431
            :.|   ||.||
pombe   447 IQFRPMSVKAE 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pol31	NP_647659.1	MPP_PolD2_C	175..426	CDD:277333	92/269 (34%)
cdc1	NP_594406.1	HYS2	1..460	CDD:224230	149/466 (32%)
		MPP_PolD2_C	185..449	CDD:277333	94/277 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	120	1.000	Domainoid score	I1461
eggNOG	1	0.900	-	-		E1_COG1311
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	198	1.000	Inparanoid score	I1008
OMA	1	1.010	-	-		QHG54495
OrthoFinder	1	1.000	-	-		FOG0005088
OrthoInspector	1	1.000	-	-		oto100902
orthoMCL	1	0.900	-	-		OOG6_102286
Panther	1	1.100	-	-	LDO	PTHR10416
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R344
SonicParanoid	1	1.000	-	-		X3610
TreeFam	1	0.960	-	-
	13	12.860