Protein Alignment Pol31 and Pold2

DIOPT Version :9

• Sequence 1: NP_647659.1
• Gene: Pol31 / 38228
• FlyBaseID: FBgn0027903
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_001348871.1
• Gene: Pold2 / 18972
• MGIID: 1097163
• Length: 469
• Species: Mus musculus
• Alignment Length: 433
• Identity: 188/433 - (43%)
• Similarity: 264/433 - (60%)
• Gaps: 25/433 - (5%)

  Fly     9 YENLSSIFRLKGHDYQKQFFHLYAHRLAEMTRLLTPLAQKKWGNKEPIKKLCELR-GEQDVHCIL 72
            |.|.|..|||....:.:|:.|:||.||.:|...|...||:.||::..:||||||: |||   |.:
Mouse    32 YTNSSQPFRLGERSFNRQYAHIYATRLIQMRPFLVSRAQQHWGSRVEVKKLCELQPGEQ---CCV 93

  Fly    73 IGTIFKHQAHKPSILRDISEENQLAPQPPRQNYSDPEDKIVLEDELQRVRLQGKLNGQLLATGVV 137
            :||:||..:.:|||||:||||:.|.|||||..|..|:|::||||||||::|:|.::...|.||.|
Mouse    94 VGTLFKAMSLQPSILREISEEHNLVPQPPRSKYIHPDDELVLEDELQRIKLKGTIDVSKLVTGTV 158

  Fly   138 CAALGGTDSDGFFNVEDILFYESGPQKPLAPIKRSRLLVLASGL--------DQLQAHKFVEALN 194
            .|.||....||.|.|||..|.:..||||:.|:...|.::|.|||        ..|.....|:.
Mouse   159 LAVLGSAKDDGRFQVEDHCFADLAPQKPVPPLDTDRFVLLVSGLGLGGGGGESLLGTQLLVDV-- 221

  Fly   195 LFQYWLAGSLGNNKE---AGSMVRLIVAGNSVRASAMAHVPTLQVAR--TQANANDTVQAVSQLD 254
                 :.|.||:..|   |..:.|:|:|||.:..:..:. .::..|:  |:.....:|:||..||
Mouse   222 -----VTGQLGDEGEQCSAAHVSRVILAGNLLSHNTQSR-DSINKAKYLTKKTQAASVEAVKMLD 280

  Fly   255 QWFASWARSLPVDIMPGPYDPANFMLPQQPFHKCMFPQAAQLATFQAVTNPYSCRLDEALVVGTS 319
            :.....:.|:|||:|||.:||.|:.|||||.|.||||.|...:|.|.|||||...:|....:|||
Mouse   281 EILLQLSASVPVDVMPGEFDPTNYTLPQQPLHPCMFPLATAYSTLQLVTNPYQATIDGVRFLGTS 345

  Fly   320 GQNVSDLLRSTSLDSALEALRCTLTWGHVAPTAPDTLACYPYIESDPFILRECPHVYYAGNCESF 384
            ||||||:.|.:|::..||.|..||...|::|||||||.|||:.::||||..||||||:.||..||
Mouse   346 GQNVSDIFRYSSMEDHLEILEWTLRVRHISPTAPDTLGCYPFYKTDPFIFPECPHVYFCGNTPSF 410

  Fly   385 ATELHEGSEGKRTRLVCVPSFSKTQSVAVVDLDTLDCRMVNFS 427
            .:::..|.|.:...||.||.||.||:..:|:|.:|.|:.::|:
Mouse   411 GSKIIRGPEDQVVLLVAVPDFSSTQTACLVNLRSLACQPISFA 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pol31	NP_647659.1	MPP_PolD2_C	175..426	CDD:277333	107/263 (41%)
Pold2	NP_001348871.1	MPP_PolD2_C	215..452	CDD:277333	102/244 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847115
Domainoid	1	1.000	173	1.000	Domainoid score	I3693
eggNOG	1	0.900	-	-		E1_COG1311
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4538
Inparanoid	1	1.050	351	1.000	Inparanoid score	I2252
Isobase	1	0.950	-	0	Normalized mean entropy	S1954
OMA	1	1.010	-	-		QHG54495
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005088
OrthoInspector	1	1.000	-	-		oto92854
orthoMCL	1	0.900	-	-		OOG6_102286
Panther	1	1.100	-	-	LDO	PTHR10416
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R344
SonicParanoid	1	1.000	-	-		X3610
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740