Protein Alignment CG13933 and LOC1277193

DIOPT Version :10

• Sequence 1: NP_647658.1
• Gene: CG13933 / 38227
• FlyBaseID: FBgn0035270
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: XP_001688931.2
• Gene: LOC1277193 / 1277193
• VectorBaseID: AGAMI1_014198
• Length: 755
• Species: Anopheles gambiae
• Alignment Length: 755
• Identity: 518/755 - (68%)
• Similarity: 587/755 - (77%)
• Gaps: 84/755 - (11%)

  Fly     1 MGGSVSQVFRSGSALLSHRDG-KLSKATEETIQTLFDILRANPKVSLQTLESLLIQIPKNENILA 64
            |||||||||||||||||:||| |:|:.|.|.:.|:||.||||||:|:|.||.||:||||.|||||
Mosquito     1 MGGSVSQVFRSGSALLSNRDGHKVSETTVEKVNTIFDALRANPKISIQRLEPLLLQIPKYENILA 65

  Fly    65 MHDDYGYNILQRSVGLNHIDLTKWLLHRHRPDVNRSPCSLPLHIATLRGYEECVELLLRHGARID 129
            :||:.|||:||:||||||::|.:|||.|||||||||.||||||||.|:||||||||||:||||||
Mosquito    66 IHDETGYNLLQKSVGLNHVELARWLLQRHRPDVNRSSCSLPLHIACLKGYEECVELLLKHGARID 130

  Fly   130 VDTRMCFPGAHTRNCEESGKWHNNVDD--VSERLNTKLQNALFYAIDGDQYNVLSLLTQKMEEPW 192
            .:.||||||||:.|||||||:.|..||  |.||.|||||||:.|||||||.|||::|.|||||||
Mosquito   131 TEARMCFPGAHSHNCEESGKYKNQGDDVRVCERPNTKLQNAVCYAIDGDQINVLNILAQKMEEPW 195

  Fly   193 IPFRVKKPLLHLACERGAWNCVQQLVVTRSEEINLIMDEYYPIHHAVLHDGRFLELLIHQGAITT 257
            :||||:|||||:|||||||.|||.||.|||:|||||.|||||||.|||||||||||||..|||||
Mosquito   196 MPFRVRKPLLHIACERGAWKCVQHLVQTRSDEINLIKDEYYPIHQAVLHDGRFLELLIQHGAITT 260

  Fly   258 VRTCTQQMTLLHVVIFAARKSAEDTLATLRILLERGCKELINAPDSLGNTPLHALIVRYALEEAR 322
            |||||||||||||||.||||||||||.|:|||||||||||||:|||||||||||:||||||||||
Mosquito   261 VRTCTQQMTLLHVVILAARKSAEDTLTTIRILLERGCKELINSPDSLGNTPLHAIIVRYALEEAR 325

  Fly   323 YGYDKWSKWDVLHLVRFLLQNGAKQSINQAGNSAMACVFRHLRDWEVCYELLSMLIKENGDPNIV 387
            ||||||:|||||||||||||||||.||||.||||:||||||:||||||||||:|||||.||||||
Mosquito   326 YGYDKWNKWDVLHLVRFLLQNGAKSSINQTGNSALACVFRHIRDWEVCYELLNMLIKEGGDPNIV 390

  Fly   388 GRDGSVPIMVLLVPLINKDHLHHFTHSMKVCYLNCIRMLLQHGANPNCSYRANLKPLHVLVFTVS 452
            ||||||||||.||||||||.|||||||||||||||||:|||:|||||||||:||.|||||:||||
Mosquito   391 GRDGSVPIMVCLVPLINKDPLHHFTHSMKVCYLNCIRILLQNGANPNCSYRSNLTPLHVLIFTVS 455

  Fly   453 ENFTLNCDAQKRTNFDFIKNILLMLLQHGLDCNKTYQHILQAVMDMVHNVRTCHDMECVYELTLT 517
            ||||||||.|||.||||||||||:|||:|||||.|.|||||:|:||:.|||||.|:.|||||.|.
Mosquito   456 ENFTLNCDIQKRANFDFIKNILLLLLQYGLDCNITSQHILQSVIDMIVNVRTCPDILCVYELLLL 520

  Fly   518 LIQYGADPNIVLSGK-------TTPGTAIFSNELATF---------------------------- 547
            |||||.||||.||.|       ::..:.||.|:...|
Mosquito   521 LIQYGIDPNISLSNKLMANGASSSNSSIIFVNDFINFGGIRGAAPGGAVDAAASGGASSTGGPSN 585

  Fly   548 ---------------------------------------------RSSFRTNS-CYLLFYYIILI 566
                                                         |||||.|: .|||||||:||
Mosquito   586 GGPGGVVVTGGAGGGGGGASSAANGNGGGPGGSGTGGPSNGNENLRSSFRNNARNYLLFYYIMLI 650

  Fly   567 TKKEFILNDPNATYTRVIHLFYLTMHHEPLFNCLKSLHNFYVAQVPSKKTEQLIALISSLYRRPR 631
            |:|||||.|...||.|:|:|||.:|.|||||||||:|||..:||||.:..:.|..||.:||::||
Mosquito   651 TRKEFILLDREQTYQRIIYLFYYSMKHEPLFNCLKTLHNLLIAQVPHRSIDNLRHLIITLYKKPR 715

  Fly   632 SLKQLSRWAIYEAMNRKLAQNINCLNLPGPLKDYVLQFER 671
            |||||.|..||.::::|||.||..||||||||:||:.|::
Mosquito   716 SLKQLCRVCIYNSLDKKLAPNIARLNLPGPLKEYVMNFDK 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13933	NP_647658.1	ANKYR	<67..250	CDD:440430	143/184 (78%)
		ANK repeat	69..98	CDD:293786	20/28 (71%)
		ANK repeat	99..130	CDD:293786	26/30 (87%)
		ANK repeat	165..190	CDD:293786	18/24 (75%)
		ANKYR	179..>448	CDD:440430	236/268 (88%)
		ANK repeat	234..260	CDD:293786	22/25 (88%)
		ANK repeat	262..302	CDD:293786	35/39 (90%)
		ANK repeat	304..349	CDD:293786	41/44 (93%)
		ANKYR	<372..>535	CDD:440430	134/169 (79%)
		ANK repeat	390..434	CDD:293786	39/43 (91%)
		SOCS_box	630..667	CDD:462192	24/36 (67%)
LOC1277193	XP_001688931.2	None