DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhc62B and Dnah3

DIOPT Version :9

Sequence 1:	NP_995958.2	Gene:	Dhc62B / 38226	FlyBaseID:	FBgn0013811	Length:	3964	Species:	Drosophila melanogaster
Sequence 2:	NP_001357735.1	Gene:	Dnah3 / 381917	MGIID:	2683040	Length:	4072	Species:	Mus musculus

Alignment Length:	4116	Identity:	1705/4116 - (41%)
Similarity:	2473/4116 - (60%)	Gaps:	293/4116 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MYTKKLERMHRP----------------ASDITKYDNEPYMKNPLLKFRISEVHERRHYQFLKQK 49
            |..|.|.::::|                |...:|...||..|.  :||.:....:.....|:.:.
Mouse    92 MKLKDLLKVYQPVTISIPRDKTSQGLPLAFTASKTSTEPSKKK--MKFNLKAKDDVTGMPFVCKF 154

  Fly    50 AADVKVRVARQQWQPEPDMR-LLPQSHYEDNLRREVRKIVVPPMLRRTEAKILSFASERLKNKYP 113
            ::.:.::.........|:.| :.|:...:..|::|:          ..|:|....:...|:..|.
Mouse   155 SSSLSIKNTTDSSVTHPESRPMSPEQQMDVMLQQEM----------EIESKEQKPSELDLERYYY 209

  Fly   114 ELVQAYMHDV----HEEFNRLMKVYSM--KNILRHPEFSDEDPAQFELPRPDIGFRRPGRTQNYS 172
            .|......|:    :||.  :|::|.:  |.:|..|..   :|.|       :..|....:..|.
Mouse   210 YLTNGIRKDMIAPENEEV--MMRIYKLIPKTLLTTPAL---EPLQ-------VSLRSEKESDYYY 262

  Fly   173 NFLEN-----------RRRIAQKLLILQLPLRAI-----------------------LNISVGEL 203
            :.:::           ::|:..|.:....|.|.|                       :|..:.:|
Mouse   263 SLMKSIVDYILMDPMEKKRLFIKSIPRLFPHRVIRAPVPWHNIYQSTKKWNEEHLHTVNPMMYKL 327

  Fly   204 PKLACI----FNYVLATGAMQQQLGLGGREALSYKFYHKYIQNQLDKVNTFLRWTWYPKIVQ--V 262
            .:|...    ..:|.....:..:|.|...|      |.:.:|....:....|...|.|...|  |
Mouse   328 KELWFAEFQNLRFVRTADLLAGKLPLLPHE------YKEVVQKHCREARHILLTKWIPTCAQLFV 386

  Fly   263 LRKLMRKRVMPMSTWKRSWNAME------ALMNREMTNMKIRT----------------FEEMYR 305
            .:|.......|.:.:..|.|..|      :.|:.::.::.|::                |:|.|:
Mouse   387 TQKEHWVHFAPKNDYDSSRNIEEYFASVASFMSLQLRDLVIKSLRDLVSFFMIHKDGNDFKEPYQ 451

  Fly   306 MCSH--PRTMPMMRMSLEWSE----FSSDLDTRPNAWSILR-TFAEIATEISMVGYRMEPLQPQV 363
            ....  |:   ::.:.||..:    |:...|   :.|.::: :|.||......:        |:|
Mouse   452 EMDFFIPQ---LIMIKLEVRDPIIVFNPTFD---DCWQLIKNSFLEIIKNSDGI--------PKV 502

  Fly   364 QTL--TSMAAYAKVNDYLKIEMNDNFLKDVIDKVQNIILRTYQEVIQYVEGFRDKYYALYSWQER 426
            :::  ..:..|..:...:..|  ::.:.|.:|:...:..:......:|:..:: ||..|......
Mouse   503 ESILFPDLKGYNMILGTVNPE--ESLVSDFLDQTLEVFKKNQVGPYKYLNVYK-KYDDLLDNMAE 564

  Fly   427 DALNQFLSEPHEFEEYFARIDMYYGFIQMLRSE--------PATEYFVMAVIHNEPAIFGLRTLA 483
            ..:::||.|.||.|::...|:.    |:..::|        |...:.:.||..|    :.|...|
Mouse   565 KGISEFLKEKHEIEDFVTSINS----IKKRKNEIASMHITVPLAMFCLDAVFLN----YDLCERA 621

  Fly   484 ENLIHEITTIIIREHIKAEVDICDEFEKIKYRALEIPKSTEELLESAEYM-------IHVKKDKI 541
            :||...:....:..:.:....||:::..|..:..|||.:|.||:...||:       :...:.::
Mouse   622 QNLKDNLILYQVDVNRETNTSICNQYSTIADKVSEIPANTAELVALIEYLKKSSDVTVFKLRRQL 686

  Fly   542 AELTDRIQYCLQVGTNIVELTEMSKYHFDLTIKTINWIKDINDICDYN----ASQQEQFKF---- 598
            .:.::|:::       :::..::......|......|...|.|:.:.:    .|:::|.:.
Mouse   687 RDASERLEF-------LMDYADLPNEDIKLNSNLFLWPDQIEDVFESSRNLLMSKRDQAEMDLIK 744

  Fly   599 ---TFEEHLQEVIKKLNSDIDELLPKLTVIDDMSRPDKFRDSYIILQNFIDQLKTFDDYVAWINK 660
               .||..|:...|:|     |:..|..|:......:.....:.:.:|....|..|:    .|||
Mouse   745 RCSEFESRLEGYSKEL-----EMFRKREVMTTEEMKNNVEKLHDLSKNLDLALTEFE----LINK 800

  Fly   661 EEKLFKVALTEYPKLDIIKTFVYPFAELMKCCIEWQRYLSVWNDGPFEYL--EPQFVE------R 717
            ||:|.:...:.:|.|..:.....|:.:|.....|:......|.:||. ||  ..|..|      |
Mouse   801 EEELLEKEKSSFPLLQTLMINKIPYEQLWVTAYEFSTKSEEWMNGPL-YLMNAEQIAEEIGNMWR 864

  Fly   718 TTDDYLKEFQKNQKYYRVKIKQDLIDNPVCKFKGQTEDPDPAKHPVPLRLCTSMIQSIKDFTTGV 782
            ||               .|:.:.|||                 .|.|.||..::...|:.|...:
Mouse   865 TT---------------YKLTKTLID-----------------VPAPKRLAENVKLKIEKFKQHI 897

  Fly   783 FIVNTMCNPALRKRHWKEMSEIAGFDVTPDAGTTLRKILNSGLDPILDQFEIISIGANKELQLWN 847
            .|:|..|||.::.|||:::|:|.|:::.|...|.|..:|..|....:|:.|.|...|:||..|..
Mouse   898 PILNIACNPGMKDRHWQQISDIVGYEIKPTETTCLANMLEYGFGKFVDKLEPIGAAASKEYSLEK 962

  Fly   848 ALQAMIKEWETRVFPYGPYKETGVQILSSLDDIQALLDDHILKTLVMRGSAFMKPCEEEVRAWYE 912
            .|:.|..:|....|.:..|::|...||.::||||.:||||::||..|.||.|:||.|.|.|.|.|
Mouse   963 NLEKMKADWVNMCFSFVKYRDTDTSILCAVDDIQLILDDHVIKTQTMCGSVFIKPIEAECRKWEE 1027

  Fly   913 KIMRVNETLDQWGKVQANYLYLLPIFSSKDIVAQMPEEGRLFVIVEQTYTRNMGLVLRQPLVMET 977
            |::||.|.||.|.|.|..:|||.|||||:||:|||||||:.|..|:..:...|...:....||..
Mouse  1028 KLVRVQENLDAWLKCQVTWLYLEPIFSSEDIIAQMPEEGKKFTTVDTYWKSLMAQAVNDTRVMVA 1092

  Fly   978 APVSGLLESLQKANELLEDIATGVSNYLEKKRLYFPRFFFLANDEMLEILSETKDPLRVLPHLSK 1042
            |....:.|.||:||.|||||..|:::|||||||:|||||||:|||:|||||||||||||.|||.|
Mouse  1093 ADQPRMTEKLQEANVLLEDIQRGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLKK 1157

  Fly  1043 CFEGINSLEFDAAKNVLAMISSDKETIEFIEQVSTAAAGGSVEKWLIGVEDEMLKAVRYQNELSF 1107
            |||||..|||.....:..||||:|||:.||:.:....|.|.|||||..||..||.::|...|...
Mouse  1158 CFEGIAKLEFTDNLEIKGMISSEKETVPFIQTIYPVKAKGMVEKWLQQVEQVMLASMRQVIENGI 1222

  Fly  1108 AHYPKVKRHEWVLEWPQMTVLAISQVYWASRVHGCLRRTFGGNMTIMMNFFQELSKELNDIVTLV 1172
            ..|.:|.|:.||||||...|:.:|.::|...|...|..      ..:.:|.::.:.::..||.||
Mouse  1223 EAYVQVPRNAWVLEWPGQVVICVSSIFWTREVSEALVE------DTLTDFLKKSNDQIAQIVELV 1281

  Fly  1173 RSPKISNLNRITIKSLIVIDVHAKDVSEDLIKNKVSSEFDFQWLAQMRYYWEDDKTWVRIINATV 1237
            |. |:|:..|:|:.:|.||||||:||...|..:.::|..||||::|:||||.:....|::|....
Mouse  1282 RG-KLSSGARLTLGALTVIDVHARDVVAKLRHDHINSLNDFQWISQLRYYWTEKNVHVQMITTEA 1345

  Fly  1238 PFANEYLGNSDRLVITPLTDRCYRTLVGAYQLHLNGAPEGPAGTGKTETTKDLAKALAVQCKVFN 1302
            .:..||||||.|||||||||||||||:||.:|:|.|||||||||||||||||||||||.||.|||
Mouse  1346 LYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFN 1410

  Fly  1303 CSDGLDYKAMGKFFKGLASCGAWACFDEFNRIELEVLSVVAQQILLIIQAVRSNATKFMFEGTEL 1367
            ||||||||||||||||||..|||||||||||||:|||||||||||.|.||:.....:|:||||||
Mouse  1411 CSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRKLKRFIFEGTEL 1475

  Fly  1368 TLNPACYVCITMNPGYAGRSELPDNLKVLFRSVAMMVPDYAMIGEISLYSYGFVDARKLAVKIVT 1432
            :|||.|.|.||||||||||:|||||||.|||:|||||||||:||||||||.||:|:|.||.|||.
Mouse  1476 SLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVA 1540

  Fly  1433 TYRLCSEQLSSQNHYDYGMRAVKTVLSACGNIKKQYPDEVEDILLLRSLIDVNLPKFLSFDVPLF 1497
            ||||||||||||:||||||||||:||:|.||:|.:||:|.|.:||||:|:||||.|||:.|||||
Mouse  1541 TYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLF 1605

  Fly  1498 EGIISDIFPGIKLPHIDYSLVESEFKRVCLEEVLEPAPSFLLKVIQTYEMIIVRHGFMLVGEPLA 1562
            :|||||:|||:.||..||.:..........:..|:|.|.|:.|:||.|||::||||:|:||:|:.
Mouse  1606 QGIISDLFPGVVLPKPDYEVFLEALNNNIRKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMG 1670

  Fly  1563 GKSKTLQVLAKVLSALKIKAPQKSNYFQHVQMGIMNPKSITMNQLYGSFDPISYEWTDGLVAKIF 1627
            ||:...:|||..|..|. .|.|...:  .|:..|:|||:|||.||||.||.:|:|||||::|..|
Mouse  1671 GKTSAYKVLAAALGDLH-AANQMEEF--AVEFKIINPKAITMGQLYGCFDAVSHEWTDGVLANAF 1732

  Fly  1628 RDFAMTPTPDRKWVIFDGPVDAVWIENMNTVLDDNKKLCLTSGEVITMSNEMSMVFEVMDLAQAS 1692
            |:.|.:.|.||||:||||||||||||||||||||||||||.|||:|.||::||::||..||.|||
Mouse  1733 REQASSITDDRKWIIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSSKMSLIFEPADLEQAS 1797

  Fly  1693 PATVSRCGMIYMEPSTLGWRAFAKSWLKKADPRWADEEGVPYVMALMQWLLPPCQTFVRRFCSQF 1757
            |||||||||||||...|||:....|::... ||...:|....|..:..||:.||..|.|..|...
Mouse  1798 PATVSRCGMIYMEAHQLGWKPLKDSYMDTL-PRCLTKEHTELVEDMFTWLVQPCLDFSRLHCKFV 1861

  Fly  1758 IKPG----EFNCMLTTFDLFDMQIAEAIEENPEDYQ----KYLQTYFQAAILFALIWGVGGVLDT 1814
            ::..    .|:.|.....|.| :|.:..||..|.|:    :.:..:.|...||:|:|.:.|.::.
Mouse  1862 VQTSPIHLAFSMMRLYSSLLD-EIRDIQEEEMEIYEGLSSQQIFLWLQGLFLFSLVWTLAGTINA 1925

  Fly  1815 ASREKFDVFLKKLW----DTDPPPPE-PLGKMEITPPTEGLLVDYVFLYKQRGAWRYWPDLAKRM 1874
            .||:|||||.:.|.    |.:|.|.. .|.|..|. |..|.:.|:.||.:..|.|..|.:...:
Mouse  1926 ESRKKFDVFFRNLIMGMDDRNPRPKSVKLTKNNIF-PERGSIYDFYFLKQGGGHWNAWTEYITK- 1988

  Fly  1875 DVEET------KTGVIVPTVDTARYIHLLKMHVEHKKRMLLVGPTGTGKTVYVQNYLMNKLDKEV 1933
             .|||      .:.:|:||::|||....||.:::|:..:|.||||||||:....::|:: |.|.|
Mouse  1989 -EEETIPANAKVSDLIIPTMETARQSFFLKTYLDHEIPILFVGPTGTGKSAITNDFLLH-LPKNV 2051

  Fly  1934 FETGFITFTVMISANQCQDLLISKLQKWKRGIYGPPKGMQSVLFVDDMNMPVKEVYGAQPPLELL 1998
            ::..||.|:...||||.||:::|||.:.::|::|||.|.::|:||||:|||.|||||||||:|||
Mouse  2052 YQPNFINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELL 2116

  Fly  1999 RQFFDYGHVYDLKDSSKVYIHNVLIMAACGLPGGSRQDVYARFLNHFNVYSINTFSDDSMFRIFL 2063
            ||:.|:|:.:|.||::::.|.:||::.|.|.|||.|.|:..||..|.|:.|||.|.|:.:.:||.
Mouse  2117 RQWIDHGYWFDKKDTNRLDIVDVLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDEILTKIFS 2181

  Fly  2064 NVALNGFRRAGHGQDVFVVT--NQIVSATQSIYKSVQSEIRATPSKSHYIFNLRDISRVVTGCTL 2126
            ::|...|   |.|.||..:.  ..:|.|||:||::.......|||||||:|||||.|||:.|..|
Mouse  2182 SIADWHF---GKGFDVMFLRYGKMLVQATQTIYRAAVENFLPTPSKSHYVFNLRDFSRVIQGVLL 2243

  Fly  2127 VRKESVSDKKIFVRVWYHEAMRVFYDRLVDDVDRKWMFDKLNECLKANFKDKVETVFERYCVQGP 2191
            .....:.|.:.|:|:|.||..|||||||:|:.||:..|:.:.|.....||..:|.|.......|.
Mouse  2244 CPHTHLQDLEKFIRLWIHEVYRVFYDRLIDNDDRQTFFNLVKETTSNCFKQTMEKVLIHLSPTGK 2308

  Fly  2192 DEAVFTMEAASNILFGVYFDEDSVPDERRYEEVPSVEVFLNLALTSLDDYNSTRRNKMDITLFTF 2256
                .|.:...::.||.|...:|  |::.|:|:..:.....:....||::||..:..|.:.:|.|
Mouse  2309 ----ITDDNIRSLFFGDYLKPES--DQKIYDEIIDLRGLTVVMEYYLDEFNSVSKAPMSLVMFKF 2367

  Fly  2257 ALQHLNRICRIISIQGASALIIGLGGSGRQSLTKLATNMVQTSFFQPEITKNYGANDWHDDIKAI 2321
            |::|::||||::..:....|::|:|||||||.|||:|.|.....:|.||||||..:||.:|:|.|
Mouse  2368 AIEHISRICRVLKQKKGHLLLVGIGGSGRQSATKLSTFMNSYELYQIEITKNYTNSDWREDLKKI 2432

  Fly  2322 LKEAGGMNKHTTFLITENQIKMELFLQDIDCLLNQGEVPNIFPIDEKQEVLEMVRLAAQGGNRNI 2386
            :.::|...|.|.||.::||||.|.|::||:.|||.|:||||||.|||.:::|.::.||:.....:
Mouse  2433 MLQSGVATKSTVFLFSDNQIKHESFVEDINMLLNTGDVPNIFPADEKADLVEKMQTAARTEGEKV 2497

  Fly  2387 DVSALQVFSFFVDRCKQKLHMILSFSPIGDALRTRVRLYPSLVNCCTIDWYDSWPEEALQMIAKM 2451
            :.:.|.:::||::|.::.||::|:.||||||.|||:|::|||:|||||||:.|||.:||:::|..
Mouse  2498 EATPLSMYNFFIERVRKNLHIVLAMSPIGDAFRTRLRMFPSLINCCTIDWFQSWPTDALELVANK 2562

  Fly  2452 SLVDVNVPSEDIKLAIMDTCQYFHTTAARSTRAFCQMTGRHIYQTNASFIELIRSFQTLIERKQS 2516
            .|.||.: .::|:..::..|:||..:..:.:..:.....||.|.|..|::|||.:|:||:..|:.
Mouse  2563 FLEDVEL-DDNIRAEVVSMCKYFQESVKKLSVDYYNTLLRHNYVTPTSYLELILTFKTLLNSKRQ 2626

  Fly  2517 ETMLAKMRYIGGLDTLAQAAAAISIMQRDLNALQPKLVALAESSRKMMLEINKETLAASAAAEQV 2581
            |....:.||:.||..|..|::.:::||.:|.||||:|:..:|.:..||::|..||..|.|....|
Mouse  2627 EVDTIRNRYLAGLQKLEFASSQVAVMQVELTALQPQLIQTSEDTAMMMVKIELETKEADAKKLLV 2691

  Fly  2582 KRDEEVASVQAEAAQVLKQDCERDLAKAIPVLEDALAALNTLKPADITLVKSMKNPPPVIKLVMA 2646
            :.||:.|:..|..:|.:|.:||.|||:|:|.||.|||||:||.|:||||||||:|||..:||||.
Mouse  2692 QADEKEANAAAAISQAIKNECEGDLAEAMPALEAALAALDTLNPSDITLVKSMQNPPGPVKLVME 2756

  Fly  2647 AVCVIKGIPPERIPDPA-SGKMVQDYWGPSKRLLGEMNFLPGLKEFDKDNIPTEIVKRIHKEFIP 2710
            ::||:||:.|||.|||: ||||::||||.|:::||::.||..||.:||||||:.|:|||.:.||.
Mouse  2757 SICVMKGLKPERKPDPSGSGKMIEDYWGVSRKILGDLKFLESLKTYDKDNIPSVIMKRIRERFID 2821

  Fly  2711 NKDFDPKVVAKASSAAKGLCQWIIAMMMYDEVAKVVAPKKAKLAGAEKEYADTMEFLAQKRALAL 2775
            :.||.|.|:...|||.:|||:|:.||.:||.||||||||:.:|..||.:....|:.|.||||...
Mouse  2822 HPDFQPAVIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLEIQMQKLNQKRAELK 2886

  Fly  2776 ALEEKVALLNIELDKANAEMQKTEEHAESCRNKLLRAEALIGGLGGEKSRWNKAAEDLQELYDHL 2840
            .:|:::..||.|.:..|.:....|::.|.|..||:|||.||.||||||.||.:||..|...||:|
Mouse  2887 LVEDRLQDLNDEFELMNRKKNSLEKNIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYDNL 2951

  Fly  2841 PGDVLISCGIIAYLSAVNLQYRSECVKDWFKKVTDLKIPCSSHYSITDVLGLEVTIQNWQLDGLP 2905
            .||||::.|.:|||.|..:.||::|..:|.....|..||.|..:|:::.||..:.|:.||:.|||
Mouse  2952 TGDVLLASGTVAYLGAFTVDYRAQCQNEWLVSCKDKVIPGSVDFSLSNTLGDPIKIRAWQIAGLP 3016

  Fly  2906 NDEFSSENAIISANSSRYSLFIDPQAQANNWLKNMERKNRLNCVKFNQSNYMKVIAEALEYGTPV 2970
            .|.||.:|.||.:||.|:.|.||||.|||.|:||||:.|:|:.:||:.:||::.:..||::||||
Mouse  3017 VDSFSVDNGIIVSNSRRWPLMIDPQGQANKWVKNMEKTNKLSVIKFSDTNYVRTLENALQFGTPV 3081

  Fly  2971 IIENVQEELEVPLDPILMRQTFVQGGIKHISLGESVVPVNPNFRLYMTCNLRNPHFLPETFNKVT 3035
            ::|||.|||:..::|||::.||.|.|::::.|||:::..:..|:.|:|..|||||:|||...||.
Mouse  3082 LLENVGEELDAFIEPILLKATFKQQGVEYMRLGENIIEYSREFKFYITTRLRNPHYLPEVAVKVC 3146

  Fly  3036 VINFALTQNALMDQLLSIVVAKERPDLQELRITLTTEAAANKGALRDAENMILKTLS-AGGDILE 3099
            ::||.:|...|.||||.||.|||:|:|:|.:..|..|:|.||..|::.|:.||:.|| ..|:|||
Mouse  3147 LLNFMITPLGLQDQLLGIVAAKEKPELEEKKNKLILESAQNKKQLKEIEDKILEVLSLCEGNILE 3211

  Fly  3100 NEAAIQILADSKGLSKDIVEKQEAAKETVAKIEAFRLNYKPVAVHSSILYYSITDLPNIDPMYQF 3164
            :|.||:||:.||.||::|.||||.|..|..:|:..|:.||||||||:.:::.|:||.:|:||||:
Mouse  3212 DETAIKILSSSKVLSEEISEKQEIASVTETQIDETRMGYKPVAVHSAAIFFCISDLAHIEPMYQY 3276

  Fly  3165 SLNWYINLYMYSIETANKSKDLPRRIKFLVDGFTRNLYNNVCRSIFEKDKLLYSFILTARILLGT 3229
            ||.|:||||:.|:..:|||.:|..||:::::.||.::|||||||:|||||||:|.:||..:|...
Mouse  3277 SLTWFINLYVQSLANSNKSDELDLRIEYIIEHFTLSIYNNVCRSLFEKDKLLFSLLLTVGLLKER 3341

  Fly  3230 GQVEMRHFAHLVTNAKESTNIPPNPDPTWITETVWLNVLRLEELKELRGIVDHFKSHLHAWQAIY 3294
            ..::...:..|:|......|..|||.|.|::|..|..::|...|::|:|:::....::..|:.||
Mouse  3342 KAIDEEVWYFLLTGGVALDNPFPNPAPEWLSEKSWGEIVRASSLQKLKGLMEDVMQNIKVWKDIY 3406

  Fly  3295 DHSSPEKQPLPPPWQDKTTAFEKIIVLKALRPDSVFLAVRLFIAESIGDQYVTPPEFDISKSYAD 3359
            |.:.|.::.||.||....| .|||.:|:.||||.:..|::.||.|::|..::..|.||:..||.|
Mouse  3407 DSAWPHEESLPSPWFFLQT-LEKIAILRCLRPDKIVPAIQNFICETMGKIFIEAPTFDLQGSYGD 3470

  Fly  3360 STALTPLVFILSPGADPLGSLLAFAE--KMGQEETFQSISLGQGQGPIATALIKNAQEMGYWVCL 3422
            |:...||:|||||||||:..||.||:  .||..:| |:|||||||||||..:|..|...|.||.|
Mouse  3471 SSCCVPLIFILSPGADPMAGLLKFADDVSMGGTKT-QTISLGQGQGPIAANMINKAIHEGTWVVL 3534

  Fly  3423 QNCHLAASWMPYLEYLWENMDT-FNTTPNFRIWLTAYPTPQFPVTILQNGVKMTNEPPTGLKENL 3486
            ||||||.||||.||.:.|.:.. .||...||:|||:||:.:|||:|||||:|||||||.||:.||
Mouse  3535 QNCHLATSWMPALEKICEEVIVPENTNSEFRLWLTSYPSEKFPVSILQNGIKMTNEPPKGLRANL 3599

  Fly  3487 MRSYNSEPINDYEFYTGCAKQDRAFTRLLYGICFFHAVVQERRKYGPLGWNIAYGFNESDLQISV 3551
            :|||.::||:|..|:..|.| ...:.:||:|:|||||:|||||.||.|||||.|.||||||:||:
Mouse  3600 LRSYLNDPISDPLFFQSCTK-PVIWQKLLFGLCFFHAIVQERRNYGALGWNIPYEFNESDLRISM 3663

  Fly  3552 LQLSMLLNQYDHVPYDAISYLTSECNYGGRVTDNWDRRLIVTILADFCNAQAVTDNRYRFASDDR 3616
            .|:.|.||.|:.||::|::|||.||||||||||:.||||::::|:.|...:..||| |..|..|.
Mouse  3664 RQIQMFLNDYEEVPFEALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKEIETDN-YHIAPGDA 3727

  Fly  3617 YILPRKTEHREILRYLDENLPSLAPPEVYGLHANSGITRDLQTTKTLLDSMILLLGSEAAGSAGA 3681
            |::|....::..:.|| ..||..|.|||:|||.|:.||:|.|.|..|...::|.|..:   |.|:
Mouse  3728 YVIPPYGSYQSYIEYL-RTLPITAHPEVFGLHENADITKDNQETNQLFQGVLLTLPRQ---SGGS 3788

  Fly  3682 GVSVEQVILDTIKQIEREMPADMDIEAAAEKYPVDYNESMNTVVVQEMERFLKLQKEIRTTCRDL 3746
            |.|.::|:.:..:.|..::|.|.::|...:||||.|.||||||:.||:.||.:|.|.:|.:..||
Mouse  3789 GKSPQEVVEELAQDILSKLPNDFNLEEVMKKYPVVYKESMNTVLRQELIRFNRLTKVVRRSLIDL 3853

  Fly  3747 AMGIKGIIVMTPDLENVMTAMKFNRIPTKWMSKSYPCLKPLGSYVQDLYKRLNWLHDWHHHGKPP 3811
            ...|||.::|:.:||.|..:|...::|..|.:||||.|||||.||.||..||.:..:|...|.|.
Mouse  3854 GRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKGPPV 3918

  Fly  3812 TFWLSGFFFTQAFLTGAMQNFARKYKIPIDTLTFDYDVL-KVETKTSPPDDGVYCNGLYLEGARW 3875
            .||:|||:|||:||||..||:||||.||||.:.|:::|. |..|..:.|:||.|..||:||||||
Mouse  3919 VFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVTPKETTMENIPEDGAYIKGLFLEGARW 3983

  Fly  3876 EWRENTLVEQFPKVLIYAMPVIFFRPVGLVDVVEGSRYRCPLYKTAERKGTLSTTGHSTNYVVPL 3940
            :...:.:.|..||:|...:|:|:.:|......:....|.||:|||:.|:|.|||||||||||:.:
Mouse  3984 DRSTSQIGESLPKILYDPLPIIWLKPGESASFLHQDIYVCPVYKTSARRGILSTTGHSTNYVLSI 4048

  Fly  3941 LLNTHVKASHWVKRSVALICQ 3961
            .|.|.:...||:.|.||.:||
Mouse  4049 ELPTDMPQKHWINRGVASLCQ 4069

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhc62B	NP_995958.2	DHC_N2	678..1102	CDD:285579	181/431 (42%)
		P-loop_NTPase	1239..1469	CDD:304359	184/229 (80%)
		P-loop_NTPase	1553..1699	CDD:304359	89/145 (61%)
		P-loop_NTPase	1874..2145	CDD:304359	123/278 (44%)
		P-loop_NTPase	2249..2511	CDD:304359	114/261 (44%)
		MT	2524..2864	CDD:289543	170/340 (50%)
		AAA_9	2898..3111	CDD:289547	104/213 (49%)
		Dynein_heavy	3253..3952	CDD:281078	334/702 (48%)
Dnah3	NP_001357735.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..37
		DHC_N2	824..1221	CDD:369852	182/429 (42%)
		DYN1	1018..3745	CDD:227570	1351/2757 (49%)
		AAA_6	1347..1673	CDD:372306	236/325 (73%)
		AAA 1. /evidence=ECO:0000250	1347..1568		180/220 (82%)
		AAA 2. /evidence=ECO:0000250	1628..1859		124/234 (53%)
		AAA 3. /evidence=ECO:0000250	1992..2240		115/251 (46%)
		AAA 4. /evidence=ECO:0000250	2351..2602		106/251 (42%)
		AAA_8	2360..2620	CDD:372310	113/260 (43%)
		Stalk. /evidence=ECO:0000250	2617..2916		142/298 (48%)
		AAA 5. /evidence=ECO:0000250	3001..3231		112/229 (49%)
		AAA 6. /evidence=ECO:0000250	3444..3668		127/225 (56%)
		Dynein_C	3767..4068	CDD:375627	133/303 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	205	1.000	Domainoid score	I2924
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56321
OrthoDB	1	1.010	-	-		D1872at33208
OrthoFinder	1	1.000	-	-		FOG0000321
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.830