Protein Alignment Dhc62B and DNHD1

DIOPT Version :9

• Sequence 1: NP_995958.2
• Gene: Dhc62B / 38226
• FlyBaseID: FBgn0013811
• Length: 3964
• Species: Drosophila melanogaster
• Sequence 2: NP_653267.2
• Gene: DNHD1 / 144132
• HGNCID: 26532
• Length: 4753
• Species: Homo sapiens
• Alignment Length: 4840
• Identity: 912/4840 - (18%)
• Similarity: 1657/4840 - (34%)
• Gaps: 1427/4840 - (29%)

  Fly     4 KKLERMHR----PASDITKYDNEPYMKNPLLKFRISEVHERR------HYQFLKQKAADVKVRVA 58
            |.|..:||    ..|.:.....:.|.....|:.|:......|      :.|.::.|..:.|::.|
Human   446 KALRLLHRCLNLCTSILRLVHEDTYHMQQCLQERVQNCDRIRTGQGSIYLQRVQHKQLEQKLKQA 510

  Fly    59 RQQWQPEPDMRLLPQSHYEDNLRREVRKIVVPPMLRRTEAKILSFASERLK--NKYPELVQAYMH 121
            ...|     ::|       ....|.|..::...::...|.:|.||.:..|:  .:.|.|....:.
Human   511 EAWW-----LQL-------GKFARLVDYMICQSLISVLEEQITSFVANILQAPRQKPFLSSQLVF 563

  Fly   122 DVHEEFNRLMKVYSMKNILR--------------------------HPEFSDED---PAQFELPR 157
            |.|.:.:.:..|.:|...|.                          :.|..||:   ..:|.:|:
Human   564 DDHGQLSHVPCVENMIQTLTGGLQSVKTSALQVVQSADLKTSSDSLYSEEEDEEEDSKDEFLMPK 628

  Fly   158 --------------PDIGFRRPGRT--------------------QNYSNF---LENRRRIAQKL 185
                          |::|...|.::                    .||...   |:|..:|.|.|
Human   629 FQGQPSDAVSIFCGPNVGLVWPWKSHPIAGILEVRGCRLRGQYFPHNYKQLEEDLDNNPKIQQAL 693

  Fly   186 LILQLPLRAILNISVGELPKLACIFNYVLATGAMQQQLGLGGREALSYKFYHKYIQNQLDKVNTF 250
            .|.|:.|..:| ..|.|.    |                   ||       |.:|..    :..|
Human   694 NIQQVLLEGVL-CKVQEF----C-------------------RE-------HHWITG----IYEF 723

  Fly   251 LRWTWYPKIVQVLRKLMRKRVMPMSTWKRSWNAMEALMNREMTNMKIRTFEEMYRMCSHPRTMPM 315
            |: :|.|:.::.:|....|..:.:.:....|.|                     |:.|.|
Human   724 LQ-SWGPQKLEDMRGGPIKNYVTLVSRLNVWQA---------------------RVSSMP----- 761

  Fly   316 MRMSLEWSEFSSDLDTRPNAWSILRTFAEIATEISMVGYRMEPLQPQVQTLTSMAAYAKVNDYLK 380
                                       .|:.|:..::......:|.:::        :|:|
Human   762 ---------------------------IELLTKGGLLLLSCHDVQAEME--------SKLN---- 787

  Fly   381 IEMNDNFLKDVIDKVQNIILRTYQEVIQYVEGFRDKYYALYSWQERDALNQFLSEPHEFEEYFAR 445
                 :..||::..|||......|:::..:..|...:..:.|  :..|:.|...:.:|..|.:..
Human   788 -----SIRKDILAHVQNECWNLSQQLMTELTDFMHIFRTINS--DIHAIAQCTQKLNEANEQYVE 845

  Fly   446 IDMYYGFIQMLRSEPATEYFVMAVIHNEPAIFGLRTLAENLIHEITTIIIREHIKAEVDICDEFE 510
            ::....:::.|..          :|.|..::|.    |||...:|:  :.|:..::.:..|.
Human   846 LEERMEYVRALHE----------LIRNHFSLFS----AENEALDIS--VRRQFGESPIPPCP--- 891

  Fly   511 KIKYRALEIPKSTEELLESAEYMIHVKKDKIAELTDRIQYCLQVGTNIVELTEMSKYHFDLTIKT 575
                     |.....||                      :|..:...::::.|..:
Human   892 ---------PPPQPHLL----------------------HCPLLAPQLLDMWEAFQ--------- 916

  Fly   576 INWIKDINDICDYNASQQEQFKFTFEEH-----LQEVIKKLNSDIDELLPKLTVIDDMSRP--DK 633
                        :..||..:|..: :.|     ||:::....::::.||.|.     :|.|  |.
Human   917 ------------FEKSQASEFLLS-KRHAIMPKLQQLMAAALAELEGLLAKA-----LSGPFMDP 963

  Fly   634 FRDSYIILQNFIDQLKTFDDYVAWINKEEKLFKVALTEYPKLDIIKTFVYPFAELMKCCIEWQRY 698
            .:|........:...:.|.:.|:.:::....:.:...:...:.:......|..:..:.   |..|
Human   964 TQDQRSTEHQLVSLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIVQQQRI---WHLY 1025

  Fly   699 ------LSVWNDGPFEYLEPQFVERTTDDYLKEFQKNQKYYRVKIKQDL-IDNPV---C-KFKGQ 752
                  :|.|....|....|...:..|:.:|.|        ..::...| :.:||   | :..|:
Human  1026 RVISENISEWKCMAFAKFSPAMAQEKTEGWLTE--------AARMSTTLELHSPVLQHCMRILGE 1082

  Fly   753 TEDPDP------AKHPVPLRLCTSMIQSIKDFTTGVFIVNTMCNPALRKRHWKEMSEIAGFDVTP 811
            .....|      :.||..|. |..:::::     |:..:.|:              |:
Human  1083 FRSYLPLLTKLGSLHPQSLN-CQCLLRAL-----GLGSLQTI--------------EL------- 1120

  Fly   812 DAGTTLRKILNSGLDPILDQFEIISIGANKELQLWNALQAMIKEWETRVF---------PYGP-- 865
               .||.::|...|....|:...:....|:.:.....::.:.:.||.|..         ||.|
Human  1121 ---LTLGQLLTYPLLEFADRINQVWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPA 1182

  Fly   866 -----------------YKETGVQILSSLDDIQALLDDH---ILKTLVMRGSAFMKPCEEEVRAW 910
                             .|::|..|||...::|..:.:.   :.|.|.:..|..:.....|   |
Human  1183 SERSKRQVLRSPQWEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALE---W 1244

  Fly   911 YEKIMRVNETLDQWGKVQANYLYLLPIFSSKDIVAQMPEEGRLFVIVEQTYTRNMGLVLRQPLVM 975
            ...:..:...|:.|...|..:::|..:.....|.....:....|.:::..|...|.:.:..|:|:
Human  1245 VAIMHGLGALLEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVL 1309

  Fly   976 -------ETAPV---SGLLESLQKANELLEDIATGVSNYLEKKRLYFPRFFFLANDEMLEILSET 1030
                   |.:|.   ..|.:.||..:..||.|...:.:.|.....:|||.|||::.|::.:|:..
Human  1310 SLVVPSAERSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAAR 1374

  Fly  1031 KDPLRVLPHLSKCFEGINSLEFDAAKNVLAMISSDKETIEF---------IEQVSTAAAGG---- 1082
            .:.......:.:||..::::.|.:..      :.:|.|.::         :|.::...|||
Human  1375 LESCEAQLWVRRCFPHVHAVSFRSCP------TGEKNTDDWESSPNTQTQVEALAVLGAGGEEVK 1433

  Fly  1083 ---------SVEKWLIGVE-------------------------DEMLKAVRYQNELSFAHYPKV 1113
                     .:.|||..:|                         .|.||.:..||:|    |.::
Human  1434 LQGPLPLHPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKL----YLQL 1494

  Fly  1114 KRHEW---VLEWPQMTVLAISQVYWASRVHGCLRRTFGGNMTIMMNFFQELSKELNDIVTLVRSP 1175
            ....|   |..:|...||...:|.|.:.:...|.. :|....:.|:.     ::|..:|..:|:.
Human  1495 YVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLE-WGTLAMVSMHM-----RKLEVLVNFMRAQ 1553

  Fly  1176 KIS----NLNRI----TIKSLIVIDVHAKDVSEDLIKNKVSSEFDFQWLAQMRYY---------- 1222
            :.|    :|..:    .:.:|:|:.|..:|:::.|.:::||...||.|:.|::|:
Human  1554 RASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKS 1618

  Fly  1223 -WEDDKT-------------WVRIINATVPFANEYLGNSDRLVITP--LTDRCYRTLVGAYQLHL 1271
             .:..||             |:.::..:..:..||||  .||...|  |.:|....|:.|.:...
Human  1619 PLQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLLALEEVA 1681

  Fly  1272 NGAPEGPAGTGKTETTKDLAKALAVQCKVFNCSDGLDYKAMGKFFKGLASCGAWACFDEFNRIEL 1336
            .|...||.|.||......||:||..|..:..||..::.:.:..:..|....|||...::.:::..
Human  1682 CGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPP 1746

  Fly  1337 EVLSVVAQQI--------LLIIQAVRSNATKFMFEGTELTLNPACYV---CITMNPGY------- 1383
            .:||.:.|::        .|..:|.|:.:|   .:.|:..|..:.:.   .:::..||
Human  1747 GLLSALGQRLGELHHLYAPLYQEASRNTST---IDPTQPQLLGSSFFEKHHVSVRLGYGCLLVLR 1808

  Fly  1384 AGRSELPDNLKVLFRSVAMMVPDYAMIGEISLYSYGFVDARKLAVKIVTTYRL----------CS 1438
            |..|.:|.||.:|.|.||:.:||...:.|::|...|..||.::|.::...:.|          |.
Human  1809 ALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCR 1873

  Fly  1439 EQLSSQNHYDYGMRAVKTVLSACGNIKKQYPD--------EVEDILLLRSLIDVNLPKFLSFDVP 1495
            ..|..|...|    .::|:     |:.|:.|.        .:|:..||||              |
Human  1874 LPLLKQILED----TIRTL-----NVTKEEPKCQKPRSLAAIEEAALLRS--------------P 1915

  Fly  1496 LF-----------EGIISDIFPG---IKLPHIDYSLVESEFKRVCLEEV----LEPAPSFLLKVI 1542
            ||           .|::..:||.   :....:.|.|:    |.:.:||:    |:|:|..|..:.
Human  1916 LFSILNGLHLHNLRGLLCALFPSASQVLAEPMTYKLM----KPLVVEELQQVGLDPSPDILGSLE 1976

  Fly  1543 QTYEMIIVRHGFMLVGEPLAGKSKTLQVLAKVLSALKIKAPQKSNYFQHVQMGIMNPKSITMNQL 1607
            |..:.:....|.:|:|...:||:.....|.|:.:.|.......:...|.|::..:.|..::..:.
Human  1977 QLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEF 2041

  Fly  1608 YGSFDPISYEWTDGLVAKIFRDFAMTPTPDRK-----------WVIFDGPVDAVWIENMNTVLDD 1661
            .|..:...  |..|:..|:.|.........:|           |:|.||..:..|::::..:|.:
Human  2042 LGWLEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSE 2104

  Fly  1662 NKKLCLTSGEVITMSNEMSMVFEVMDLAQASPATVSRCGMIYMEPSTLGWRAFAKSWLKKADPRW 1726
            ..:|.|.||:.|.......::.||.|....||..|..|.::        |....::|........
Human  2105 LPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALV--------WCGGEQTWQCILSALM 2161

  Fly  1727 ADEEGVPYVMAL----------MQWLLPP-------CQ---TFVRRFCSQFIKPG--EFNCML-- 1767
            |   .:||...|          |..:|.|       ||   :.::....|.:..|  |...|.
Human  2162 A---SLPYEYRLQHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVCAGVAEVTSMARI 2223

  Fly  1768 --TTFDLFDMQIAEAIEENPED--YQKYLQTYFQ----------------------------AAI 1800
              :..|| .:::.|.....|||  |...:...|:                            ::.
Human  2224 LHSLLDL-HLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSDDVPDKCREHLLAVSSF 2287

  Fly  1801 LFALIWGVGGVLDTASREKFDVFLK----KLWDTDPPPPEPLGKMEITPPTEGLLVDYVFLYKQR 1861
            |||||||.|..|.:.....||.|::    :|.:...|||..|.......|.:|.||.:...|
Human  2288 LFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYPEPPPSALVFDLHVSPEDGTLVPFTGQY--- 2349

  Fly  1862 GAWRYWPDLAKRMDVEETKTGVIVPTVDTARYIHLLKMHVEHKKRMLLVGPTGTGKTVYVQ---- 1922
                    |:..:   :...|...|::.|.|.::::.:.:...:.:||.|...|||:.:|:
Human  2350 --------LSSHI---KGTLGTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFVEVLVE 2403

  Fly  1923 ---NYLMNKLDKEVFETGFITFTVMISANQCQDLLISKLQKWKRGIYG-----PPKG-----MQS 1974
               .|:.:.: ...|.:..:.            ||:|      |||.|     |..|     ..|
Human  2404 PHHPYIYSPI-HPAFSSSHLR------------LLLS------RGIQGQTQASPQPGHHQDSKPS 2449

  Fly  1975 VLF-VDDMNM----PVKEVYGAQPPLELLRQFFDYGHVYDLKDSSKVYIHNVL----------IM 2024
            :|| ::|:::    |.|   ..||.||.|||..|          ..||.|:.|          .:
Human  2450 LLFLLEDLHLATSDPEK---SCQPVLETLRQAMD----------GTVYAHSTLELQTLQPTVNFL 2501

  Fly  2025 AACGLPGGSRQDVYARFLNHFNVYSINTFSDDSMFRIFLNVALNGFRRAGHGQDVFVVTNQIVSA 2089
            |...:||...:.:..|....|.|.::.:.:..::....:.:......|....:....:...:|.|
Human  2502 ATVTVPGYCERPLCPRLFRLFTVLALESMTQATLLERHVPIIQAWLERFPSVERERALARGLVRA 2566

  Fly  2090 TQSIYKSVQSEIRATPSKSHYIFNLRDISRVVTGCTLVRKESVS--------------------- 2133
            :...:::|.:....:|...||.|:|..:|.:::...|:...:.|
Human  2567 SVEAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRG 2631

  Fly  2134 -------DKKIFVRVWYHEAMRVFYDRL------------------------------------- 2154
                   ..:..||:|.|||.|.|.|||
Human  2632 TCLTVMMATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCGPGPQHLGKDHQES 2696

  Fly  2155 --------VDDVD-----RKW------------------------------------------MF 2164
                    |.:|:     .:|                                          |.
Human  2697 EEEEEEERVPEVESEGELAQWEDFSNSNSETEEEEEPYGLQVARVSNSRDPSLTPSIGPVSRGMK 2761

  Fly  2165 DKLNECLK-------ANFKDKVETVFERYCVQGPDEAVFTMEAASNILFGVYFDEDSVPDERRYE 2222
            :.::..::       :|::.:|...|:.:..:.|.     |:..|.:|..|....   |.|:..:
Human  2762 ESISHKIRQEKGTRASNYRLQVRRSFKTWWQKKPQ-----MDLISPLLLPVLLLH---PQEKPSD 2818

  Fly  2223 EVPSVEVFLNLALTSLDDYNSTRRNKMDITLFTFA---------------LQHLNRICRIISIQG 2272
            .|.|.|:.|.....:.:.|...:..|::..|.|.|               .||:.|:.|:::...
Human  2819 LVFSQELILGPNSETPNLYLERQWEKLEEQLATSAAQLKLSPHLARCHSMAQHVARLVRVLARPR 2883

  Fly  2273 ASALII-GLGGSGRQSLTKLATNMVQTSFF------QPEITKNYGANDWHDDIKAILKEAGGMNK 2330
            ...|:: |..|:||.:...||:::.|..||      :..|.:......||          .||..
Human  2884 QHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCLRDASWH----------AGMLS 2938

  Fly  2331 HTTFLITENQIKMELFLQDIDCLLNQGEVPNIFPIDEKQEVLEMVRLAAQGGNRNIDVSALQVFS 2395
            ....|:..:.:.:.. |..:..|...|..|..:...:...:.|.:.....|..:||...  .|..
Human  2939 QPVALLVPSGVDLTT-LHRLLALATSGSFPGQYTEADLDRIGEHLPRENLGVKQNIKKE--MVLQ 3000

  Fly  2396 FFVDRCKQKLHMILSFSPIGDALRTR---VRLYPSLVNCCT--IDWYDSWPEEALQMIAKMSLVD 2455
            .|..:....||:   |..|||....:   ..|:..|:...|  ||.|:.|.:.||..:|:..|..
Human  3001 RFHQQVCSHLHL---FFLIGDKQAHKQLPSTLFLRLLQLATASIDRYEPWDQAALAKVAQHHLEG 3062

  Fly  2456 V-NVPSEDIKLAIMDTCQYFHTTAARSTRAFCQMTGRHIYQ---------TNASFIELIRSF--- 2507
            . :||.:|......|......:.|  ...|...::..|.::         |..:|::.:.:|
Human  3063 AQSVPLDDGSWKYPDLQASIPSVA--KAMALIHLSATHYHEHLCPALPLVTPKTFLDFLDTFLML 3125

  Fly  2508 --QTLIERKQS----ETMLAKMRYI-------GGL-----DTLAQAAAAISIMQRDLNALQPKLV 2554
              ||:::.|..    :..|..:|.:       ..|     ..|..:..::|:.|:.|.  |.||:
Human  3126 QQQTILKIKNKAQRVQNALENLRMLIKEHGTHANLIFDLEQQLKDSGKSLSMFQQQLE--QSKLL 3188

  Fly  2555 ALAESSRKMMLE--INKETLAASAAAEQVKRDEEVASVQAEAAQVLKQDCERDLAKAIPVLEDAL 2617
                  .|..||  .::|.|..:.|.:   ||    ::||:....|:|     ::||.      |
Human  3189 ------YKQQLEECRHQENLIENLARQ---RD----ALQAQREAFLEQ-----MSKAF------L 3229

  Fly  2618 AALNTLKPADITLVKSMKNPPPVIKLVMAAVCVI----KGIPPERIPDPASGKMVQDYWGPSKRL 2678
            ..|:.|:.||...::|.:.||..:..|..|:|.:    .|                  |..:|:|
Human  3230 EPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDLFHHETG------------------WASAKQL 3276

  Fly  2679 LGEMNFLPGLKEFDKDNIPTEIVKRIHKEFIPNKDFDPKVVAKASSAAKGLCQWIIAMMMY---- 2739
            |...:|...|..|.|:.|....:.::|. .:.....|...:...|..|..|..|:.|::.|
Human  3277 LCTEDFYQELVFFPKEKITDSELIKLHL-ILKAPGMDDAALRAVSRPAASLAAWLWAVLHYGLAH 3340

  Fly  2740 ----------DEVAKVVAPKKAKLAGAEKEYADTMEFLAQKRALALALEEKVALLNIELDKANAE 2794
                      .:|...:..::|:|.        ..:|.||:     .||..:||         |:
Human  3341 CRGLPTDLLLQQVEATLTREQARLG--------YYQFQAQE-----TLEHNLAL---------AK 3383

  Fly  2795 MQKTEEHAESCRNKLL-RAEALIGGLGGEKSRW-NKAA---------EDLQELYDH---LPGDVL 2845
            |.:..:.:.:|..|.| :|:.      |:..:| .|||         ..||:|...   :.||.|
Human  3384 MVEDAQASHNCVAKTLSQAQC------GQYHKWPMKAALLTPMRAWTTQLQKLKGRCMTVFGDTL 3442

  Fly  2846 ISCGIIAYLSAVNLQYRSECVKDWF--------------------KKVTDLKIP-------CSSH 2883
            :....|.||.......|.|.:.:|.                    :|...:.||       ..|.
Human  3443 LCSAAIIYLGPFPPLRRQELLDEWLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPLLATHSP 3507

  Fly  2884 YSITDVLGLEVTIQNWQLDGLPNDEFSSENAIISA---------NSSRYSLFIDPQAQANNWL-- 2937
            :||..:|..|  .:.:|.||  |.:..:::|.::.         :|.|:.|.:||..:|..||
Human  3508 FSILSLLSSE--SEQYQWDG--NLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNEALIWLDP 3568

  Fly  2938 -----------------------------------------------------KNMERKNRLNCV 2949
                                                                 |..||||...
Human  3569 LPLEENRSFAPALTEGRGKGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQE-- 3631

  Fly  2950 KFNQSN-------------------------YMKVIA-----------EALEYGTPVIIENVQ-- 2976
            |..:.|                         |:.|::           ||...|.||::.||:
Human  3632 KEQEENEEKEEEKTESQGSKPAYETQLPSLPYLSVLSGADPELGSQLQEAAACGLPVLLTNVELG 3696

  Fly  2977 ---EELEVPLDPILMRQTFVQGGIKHISLGESVVPVNPNFRLYMTCNL----RNPHFLPETFNKV 3034
               |||:.    :|.|:..            |...|.|.|.||::..|    .......|....:
Human  3697 LGCEELQW----LLQREQL------------SPPQVQPGFCLYLSTTLSLCAMEKVLGCELLKGL 3745

  Fly  3035 TVINFALTQNALMDQLLSIVVAKERPDLQELRITLTTEAAANKGALRDAENMILKTLSAGGDILE 3099
            .|::..|....|.:|:|..::.:|.|:|:.....|...|.....|:..||..:|..|     :.:
Human  3746 NVLDLGLNMEILEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLLTML-----LFQ 3805

  Fly  3100 NEAAIQILADSKGLSKDIVEKQEAAKETVA---KIEAFRLN-------YKPVAVHSSILYYSITD 3154
            |....:   .:|.| ::||..|....:..|   ::|..:|.       |:||..|...:..:::.
Human  3806 NPKRQK---PAKFL-RNIVRAQGKLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQ 3866

  Fly  3155 LPNIDPMYQFSLNWYINLYMYSIET-----ANKSKDLPRRIKFLVDGFTRNLYNNVCRSIFEKDK 3214
            |.|:.|::..|...::.:...::::     .|..:||...:..|....||.|..:...::.....
Human  3867 LQNLLPLFCMSPENWLAVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQV 3931

  Fly  3215 LLYSFILTARILLGTGQV-EMRHFAHLVTNAKESTNIPPNP-----DPTWITETVWLNVLRLEEL 3273
            .|...:....:|..||:. |:...|.....|...:.:...|     .|.|:....|.....||.|
Human  3932 PLVGALGALALLQATGKASELERLALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHECEMLELL 3996

  Fly  3274 KELRGIVDHFKSHLHAWQAIYDHSSPEKQPLPPPWQDKTTAFEKIIVLKALRPDSVFLAVRLFIA 3338
            ....|:......|..||||....||....|.|.|..:..:..:|:|:.:.|||:.:..|:..|..
Human  3997 PPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTT 4061

  Fly  3339 ESIG---DQYVTPPEFDISKSYADSTALTPLVFILSPGADPLGSL--------LAFAEKMGQEET 3392
            ..:|   |:....|    :..:..|.|..|::.:|.|...|..:|        ||...:.||::
Human  4062 SLLGRPLDENTYAP----TMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQ- 4121

  Fly  3393 FQSISLG-QGQGPIATALIKNAQEM--GYWVCLQNCHLAASWMPYL------------------- 3435
            .|.|:|| :...|::..:...:|.|  |:|:.|.||||...|...|
Human  4122 LQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLES 4186

  Fly  3436 EYLWENMDTFNTTP---NFRIWL--TAYPTPQFPVTILQNGVKMTNEPPTGLKENLMRS------ 3489
            |.|.:..::.|.:.   :||:||  .|..:...|..:.|:.:.:.......|...|:.|
Human  4187 EQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLELGHVLIDSVELAQQ 4251

  Fly  3490 --YNSEPINDYEFYTGCAKQDRAFTRLLYGICFFHAVVQERRKYGPLGWNIAYGFNESDLQI--- 3549
              |...|             .:|...||     .|.::..|:.||            :.||.
Human  4252 VLYMQPP-------------TQALPLLL-----LHGLLLHRQLYG------------TRLQAHRG 4286

  Fly  3550 --SVLQLSMLLNQYDHV------PYDAISYLTSECNYGGRVTDNWDRRLIVTILADFCNAQAVTD 3606
              |.:.|:.:|...|.:      |..|:..|.:...|||.:.|..||..::::      .||...
Human  4287 RWSQVTLTQVLQTQDQLWASLSNPRAAMQELAASVFYGGPLGDTEDREALISL------TQACLS 4345

  Fly  3607 NRYRFASDDRYILPRKTEH-------REILRYLD---------ENLPSLAPPEVYGLHANSGITR 3655
                 .|...::.|...:.       ...||.||         ..|||...|.:.||........
Human  4346 -----PSSGSWVQPHTPQSLLATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWL 4405

  Fly  3656 DLQTTKTLLDSMILLLGSEAAGSAGAGVSVEQVILDTIKQIEREMPADMDI--------EAAAEK 3712
            ..:.::.||.::..........|.......|:.:...:.|:.|.:.:..|:        |:.|..
Human  4406 LRRQSRALLSALQRSSPVWVPESRRGAQLAERRLRQRLVQVNRRLESLQDLLTHVIRQDESDAPW 4470

  Fly  3713 YPVDYNESMNTVVVQEMERFLKLQKEIRTTCRD---LAMGIKGIIVMTPDLEN-----VMTAMKF 3769
            ..:..|.......|.|.|. |:|.:.:.|..||   |...:||    .|...:     |..|:..
Human  4471 SVLGPNARRPLEGVLETEA-LELSQLVGTLQRDLDCLLQQLKG----APPCPSRRCAAVAHALWT 4530

  Fly  3770 NRIPTKWMSKSYPCLKPLGSYVQDLYKRLNWLHDWHHHGKPPT-------FWLSGFFFTQAFLTG 3827
            .|:|..|...:....:|...:::.|.:|...|..:...|...:       |.||.|...:..|..
Human  4531 GRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLA 4595

  Fly  3828 AMQNFARKYKIPID-------TLTFDYDVLKVETKTSP-------------PDDGVYCNGLYLEG 3872
            .....|....:|..       :::......::|..::|             |:.|:...||.:..
Human  4596 LRGEAALDQNVPSSNFPGSRGSVSSQLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLH 4660

  Fly  3873 ARWEWRENTLVEQFPKVLIYAMPVIFFRPVGLVDVVEGSR----------YRCPLYKTAERKGTL 3927
            |.|:.....| :..|......:|     ||.:.....|:.          |.||:|    ..|.|
Human  4661 AEWDPIAGAL-QDSPSSQPSPLP-----PVSISTQAPGTSDLPAPADLTVYSCPVY----MGGPL 4715

  Fly  3928 STTG-HSTNYVVPLLLNTHVKASHWVKRSV 3956
            .|.. .|.|.|:.|.|.|.:..:..|:|.|
Human  4716 GTAKLQSRNIVMHLPLPTKLTPNTCVQRRV 4745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhc62B	NP_995958.2	DHC_N2	678..1102	CDD:285579	89/528 (17%)
		P-loop_NTPase	1239..1469	CDD:304359	64/259 (25%)
		P-loop_NTPase	1553..1699	CDD:304359	34/156 (22%)
		P-loop_NTPase	1874..2145	CDD:304359	61/330 (18%)
		P-loop_NTPase	2249..2511	CDD:304359	62/303 (20%)
		MT	2524..2864	CDD:289543	83/385 (22%)
		AAA_9	2898..3111	CDD:289547	58/321 (18%)
		Dynein_heavy	3253..3952	CDD:281078	172/830 (21%)
DNHD1	NP_653267.2	DHC_N2	1019..1467	CDD:285579	85/497 (17%)
		P-loop_NTPase	1649..1867	CDD:304359	57/222 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2688..2766		4/77 (5%)
		P-loop_NTPase	2870..3119	CDD:304359	56/266 (21%)
		MT	<3193..3467	CDD:289543	74/338 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	3580..3657		7/78 (9%)
		AAA_9	<3664..3802	CDD:289547	35/153 (23%)
		Dynein_heavy	3979..4741	CDD:281078	171/822 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	4669..4697		6/33 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810