DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhc62B and Dync1h1

DIOPT Version :9

Sequence 1:	NP_995958.2	Gene:	Dhc62B / 38226	FlyBaseID:	FBgn0013811	Length:	3964	Species:	Drosophila melanogaster
Sequence 2:	NP_084514.2	Gene:	Dync1h1 / 13424	MGIID:	103147	Length:	4644	Species:	Mus musculus

Alignment Length:	4302	Identity:	1065/4302 - (24%)
Similarity:	1868/4302 - (43%)	Gaps:	785/4302 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 NEPYMKNPLLKFRISEVHERRHYQFLKQKAAD---VKVRVARQQWQPEPDMRLLPQSHYEDNLRR 82
            |:.:..|.|..|.||.:...|.|:...:|..:   :.:.||                    .|::
Mouse   764 NKAHQANQLYPFAISLIESVRTYERTCEKVEERNTISLLVA--------------------GLKK 808

  Fly    83 EVRKIV------------VPPMLRRTEAKILSFASERLKNKYPEL-------------VQAYMHD 122
            ||:.::            :.|.::|....:.:|     :.|..:|             ::..|:|
Mouse   809 EVQALIAEGIALVWESYKLDPYVQRLAETVFNF-----QEKVDDLLIIEEKIDLEVRSLETCMYD 868

  Fly   123 VHEEF----NRLMKVYSMKNILRHPEFSDEDPAQFELPRPDIGFRRPGRTQNYSNF--------L 175
             |:.|    ||:.|.....|:                             .:|||.        :
Mouse   869 -HKTFSEILNRVQKAVDDLNL-----------------------------HSYSNLPIWVNKLDM 903

  Fly   176 ENRRRIAQKLLILQLPLRAILNISVGELPKLACIFNYVLATGAMQQQLGLGGREALSYKFYHKYI 240
            |..|.:..:   ||..|||...:.:|:....|   ...:.|.|.|.....||...:....:...|
Mouse   904 EIERILGVR---LQAGLRAWTQVLLGQAEDKA---EVDMDTDAPQVSHKPGGEPKIKNVVHELRI 962

  Fly   241 QNQLDKVNTFLRWTWYPKIVQVLRKLMRKRVMPMSTWKRSWNAMEALMNREMTNMKI-RTFEEMY 304
            .||:..:|        |.|.:...||.::    |..||             |..:.: |...:.|
Mouse   963 TNQVIYLN--------PPIEECRYKLYQE----MFAWK-------------MVVLSLPRIQSQRY 1002

  Fly   305 RMCSHPRTMPMMRMSLEWSEFSSDLDTRPNAWSILRTFAEIATEISMVGYRMEPLQPQVQTLTSM 369
            ::..|      ..::.|...:.:.|...|:.                      |:..:......|
Mouse  1003 QVGVH------YELTEEEKFYRNALTRMPDG----------------------PVALEESYSAVM 1039

  Fly   370 AAYAKVNDYLKIEMNDNFLKDVIDKVQNIILRTYQEVIQYVEGFRDKYYALYSWQERDALNQFLS 434
            ....:|..|:|:.:....|.|:  :.:||..|..:::        :|:.||.. |.|.|...|
Mouse  1040 GIVTEVEQYVKVWLQYQCLWDM--QAENIYNRLGEDL--------NKWQALLV-QIRKARGTF-- 1091

  Fly   435 EPHEFEEYFARIDMYYGFIQMLRSEPATEYFVMAVIHNEP-AIFGLRTLAENLIHEITTIIIREH 498
            :..|.::.|..:.:.||.:|   |:...:|...   |.|. :.|| :.|..|:
Mouse  1092 DNAETKKEFGPVVIDYGKVQ---SKVNLKYDSW---HKEVLSKFG-QMLGSNM------------ 1137

  Fly   499 IKAEVDICDEFEKIKYRALEIPKSTEEL----------LESAEYMIHVK--KDKIAELTDRIQYC 551
                    .||..      :|.||.:||          .::..::.:|:  |.||.:...::
Mouse  1138 --------TEFHS------QISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQV--- 1185

  Fly   552 LQVGTNIVELTEMSKYHFD---LTIKTI--NWIKDINDIC--DYNASQQE----QFKFTFEEHLQ 605
             ::..|...|.|..::.|.   |.|..|  .| ...|||.  ..:|.||:    |.|...|:
Mouse  1186 -ELYRNGQRLLEKQRFQFPPSWLYIDNIEGEW-GAFNDIMRRKDSAIQQQVANLQMKIVQED--- 1245

  Fly   606 EVIKKLNSDIDELLPKLTVIDDMSRPDKFRDSYIILQNFIDQLKTFDDY--------------VA 656
            ..::...:|:.....|...:....||::...:..|.:....:||  ||.              ..
Mouse  1246 RAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLK--DDREKCAKAKEALELTDTG 1308

  Fly   657 WINKEEKLFKVALTEYPKLDIIKTFVYPFAELMKCCIEWQRYLSVWNDGPFEYLEPQFVERTTDD 721
            .::..|:..:|||.|...|..:      ::||.|.   |:: :....:.|:..::|:.:.:..|.
Mouse  1309 LLSGSEERVQVALEELQDLKGV------WSELSKV---WEQ-IDQMKEQPWVSVQPRKLRQNLDG 1363

  Fly   722 YLKEFQKNQKYYRVKIKQDLIDNPVCKFKGQTEDPDPAKHPVPLRLCTSMIQSIKDFTTGVFIVN 786
            .|.:.    |.:..:::|                  .|.:....||       :|.:.....:|.
Mouse  1364 LLNQL----KNFPARLRQ------------------YASYEFVQRL-------LKGYMKINMLVI 1399

  Fly   787 TMCNPALRKRHWKEM----------SEIAGFDVTPDAGTTLRKILNSGLDPILDQFEIISIGANK 841
            .:.:.||:.||||::          ||:           ||.:|.:..|.......:.:.:.|..
Mouse  1400 ELKSEALKDRHWKQLMKRLHVNWVVSEL-----------TLGQIWDVDLQKNEAVVKDVLLVAQG 1453

  Fly   842 ELQLWNALQAMIKEWETRVFPYGPYKETGVQILSSLDDIQALLDDHILKTLVMRGSAFMKPCEEE 906
            |:.|...|:.:.:.|.|.......| :...:::...||:...:.:||.....|:.|.:.|..||:
Mouse  1454 EMALEEFLKQIREVWNTYELDLVNY-QNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEED 1517

  Fly   907 VRAWYEKIMRVNETLDQWGKVQANYLYLLPIFS-SKDIVAQMPEEGRLFVIVEQTYTRNMGLVLR 970
            ..:|.:|:.|:....|.|..||..::||..||: |.||...:|.|.:.|..:...:...|..|.:
Mouse  1518 ALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSK 1582

  Fly   971 QPLVMETAPVSGLLESLQKANELLEDIATGVSNYLEKKRLYFPRFFFLANDEMLEILSETKDPLR 1035
            .||||:...:.|:..||::..:||..|...:..|||::|..||||:|:.::::|||:..:|:..:
Mouse  1583 SPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAK 1647

  Fly  1036 VLPHLSKCFEGINSLEFDAAKNVLAMISS-DKETIEFIEQVSTAAAGGSVEKWLIGVEDEM---L 1096
            :..|..|.|.|::|:..:...:|:..||| :.|.:.|...|| ......:.:||..||.||   |
Mouse  1648 LQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVS-ITEHPKINEWLTLVEKEMRVTL 1711

  Fly  1097 KAVRYQNELSFAHYPKVKRHE------WVLEWPQMTVLAISQVYWASRVHGCLRRTFGG------ 1149
            ..:..::......:.|....:      |:.::....|:..:|:.|:..|...|....||
Mouse  1712 AKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVENALSNVGGGGDVGPL 1776

  Fly  1150 -----NMTIMMNFFQELSKELNDIVTLVRSPKISNLNRITIKSLIVIDVHAKDVSEDLIKNKVSS 1209
                 |:.:.:|.       |.|.|.:.:.|    |.|..::.||...||.:||:..|||:|:.:
Mouse  1777 QSVLSNVEVTLNV-------LADSVLMEQPP----LRRRKLEHLITELVHQRDVTRSLIKSKIDN 1830

  Fly  1210 EFDFQWLAQMRYYWEDDKT------WVRIINATVPFANEYLGNSDRLVITPLTDRCYRTLVGAYQ 1268
            ...|:||:|||:|::..:|      .:::.||...:..||||..|:||.||||||||.|:..|.:
Mouse  1831 AKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALE 1895

  Fly  1269 LHLNGAPEGPAGTGKTETTKDLAKALAVQCKVFNCSDGLDYKAMGKFFKGLASCGAWACFDEFNR 1333
            ..|.|:|.|||||||||:.|.|...|.....||||.:..|::|||:.|.||...|||.|||||||
Mouse  1896 ARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNR 1960

  Fly  1334 IELEVLSVVAQQILLIIQAVRSNATKFMFEGT-----------ELTLNPACYVCITMNPGYAGRS 1387
            :|..:||.|:||:..|.:|:|.::.. .::.|           ::.::|...:.|||||||||||
Mouse  1961 LEERMLSAVSQQVQCIQEALREHSNP-NYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRS 2024

  Fly  1388 ELPDNLKVLFRSVAMMVPDYAMIGEISLYSYGFVDARKLAVKIVTTYRLCSEQLSSQNHYDYGMR 1452
            .||||||.||||:||..||..:|.::.|||.||..|..||.|||..::||.||||||:|||:|:|
Mouse  2025 NLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLR 2089

  Fly  1453 AVKTVLSACGNIKKQYPDEV---------------------EDILLLRSLIDVNLPKFLSFDVPL 1496
            |:|:||.:.||:|::...::                     |..:|::|:.:..:||.::.|:||
Mouse  2090 ALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPL 2154

  Fly  1497 FEGIISDIFPGIKLPHIDYSLVESEFKRVCLEEVL------EPAPSFLLKVIQTYEMIIVRHGFM 1555
            ...::||:|||::....:.:.:..|.|:||.|..|      |....::.||:|.|::..:.||.|
Mouse  2155 LFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLM 2219

  Fly  1556 LVGEPLAGKSKTLQVLAKVLSALKIKAPQKSNYFQHVQ--MGIMNPKSITMNQLYGSFDPISYEW 1618
            :||...:|||...:||.|.|..|           :.|:  ..|::||:|:.:.|||:.||.:.||
Mouse  2220 MVGPSGSGKSMAWRVLLKALERL-----------EGVEGVAHIIDPKAISKDHLYGTLDPNTREW 2273

  Fly  1619 TDGLVAKIFR---DFAMTPTPDRKWVIFDGPVDAVWIENMNTVLDDNKKLCLTSGEVITMSNEMS 1680
            ||||...:.|   |........|:|::|||.||..|:||:|:||||||.|.|.:||.:::...:.
Mouse  2274 TDGLFTHVLRKIIDNVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVR 2338

  Fly  1681 MVFEVMDLAQASPATVSRCGMIYMEPSTLGWRAFAKSWLKKADP--------------RWADEEG 1731
            ::|||.||..|:.||||||||::.....|.......::|.:...              :..::||
Mouse  2339 IMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEG 2403

  Fly  1732 VPYVMALMQWLLPPCQTFVRRFCSQFIKP------------------------GEFNCMLTTFDL 1772
            ......::|         ::|..:..::|                        ....|:.:.|.:
Mouse  2404 EEAASPMLQ---------IQRDAATIMQPYFTSNGLVTKALEHAFKLEHIMDLTRLRCLGSLFSM 2459

  Fly  1773 -----------------FDMQIAEAIEENPEDYQKYLQTYFQAAILFALIWGVGGVLDTASREKF 1820
                             |.|||        |..::|:|.|    :::|::|.:.|......|.:.
Mouse  2460 LHQACRNVAQYNANHPDFPMQI--------EQLERYIQRY----LVYAILWSLSGDSRLKMRAEL 2512

  Fly  1821 DVFLKKLWDTDPPPPEPLGKMEITPPTEGLLVDYVFLYKQRGAWRYWPDLAKRMDVEETKTG--- 1882
            ..::::: .|.|.|..|      ..|    ::||.....  |.|..|.....:::||..|..
Mouse  2513 GEYIRRI-TTVPLPTAP------NVP----IIDYEVSIS--GEWSPWQAKVPQIEVETHKVAAPD 2564

  Fly  1883 VIVPTVDTARYIHLLKMHVEHKKRMLLVGPTGTGKTVYVQNYLMNKLDKEVFETGFITFTVMISA 1947
            |:|||:||.|:..||...:...|.::|.||.|:|||:.:.:.|....|.||....|.:.|.
Mouse  2565 VVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATT---- 2625

  Fly  1948 NQCQDLLIS------KLQKWKRGIYGPP--KGMQSVLFVDDMNMPVKEVYGAQPPLELLRQFFDY 2004
               .:||:.      :.::...|:...|  .|...|||.|::|:|..:.||.|..:..:||..::
Mouse  2626 ---PELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEH 2687

  Fly  2005 GHVYDLKDSSKVYIHNVLIMAACGLP-GGSRQDVYARFLNHFNVYSINTFSDDSMFRIFLNVALN 2068
            |..|...|.:.|.:..:..:.||..| ...|:.:..|||.|..|..::.....|:.:|:     .
Mouse  2688 GGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIY-----G 2747

  Fly  2069 GFRRAGHG--QDVFVVTNQIVSATQSIYKSVQSEIRAT-PSKSHYIFNLRDISRVVTGC-TLVRK 2129
            .|.||...  ..:......:.:|....|  ..|:.|.| .::.|||::.|:::|.|.|. ..:|.
Mouse  2748 TFNRAMLRLIPSLRTYAEPLTAAMVEFY--TMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRP 2810

  Fly  2130 ESVSDKKIFVRVWYHEAMRVFYDRLVDDVDRKWMFDKLNECLKANFK--DKVETVFERYCVQGPD 2192
            ......:..:|:|.|||:|:|.||||:|.:|:|..:.::.....:|.  ||.:.:
Mouse  2811 LETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDMVALKHFPNIDKEKAM---------- 2865

  Fly  2193 EAVFTMEAASNILFGVYFDEDSVPDERRYEEVPSVEVFLNLALTSLDDYNSTR-----RNKMDI- 2251
                    :..||:..:..:|.:|.::  ||              |.||...|     ..::|:
Mouse  2866 --------SRPILYSNWLSKDYIPVDQ--EE--------------LRDYVKARLKVFYEEELDVP 2906

  Fly  2252 -TLFTFALQHLNRICRIISIQGASALIIGLGGSGRQSLTKLATNMVQTSFFQPEITKNYGANDWH 2315
             .||...|.|:.||.||........|:||:.|:|:.:|::....|...|.:|.::.:.|...|:.
Mouse  2907 LVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFD 2971

  Fly  2316 DDIKAILKEAGGMNKHTTFLITENQIKMELFLQDIDCLLNQGEVPNIFPIDEKQEVLEMVRLAAQ 2380
            :|::.:|:.:|..|:...|::.|:.:....||:.::.||..||||.:|..||...::...:..||
Mouse  2972 EDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQ 3036

  Fly  2381 GGNRNIDVSALQVFSFFVDRCKQKLHMILSFSPIGDALRTRVRLYPSLVNCCTIDWYDSWPEEAL 2445
            .....:| |..:::.:|..:..:.||::.:.:|..:.|:.|....|:|.|.|.::|:..|..|||
Mouse  3037 KEGLMLD-SHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEAL 3100

  Fly  2446 QMIAK--MSLVDVNVPSEDI---------KL--------AIMDTCQYFHTTAARSTRAFCQMTGR 2491
            ..:.|  .|.:|:..|:..:         ||        ||:::|.:.|.|..::.....:..||
Mouse  3101 YQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPTHREAIVNSCVFVHQTLHQANARLAKRGGR 3165

  Fly  2492 HIYQTNASFIELIRSFQTLIERKQSETMLAKMRYIGGLDTLAQAAAAISIMQRDL----NALQPK 2552
            .:..|...:::.|..:..|...|:||....:|....||..:.:....:..::|||    ..|:.|
Mouse  3166 TMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVK 3230

  Fly  2553 LVALAESSRKMM---LEINKETLAASAAAEQVKRDEEVASVQAEAAQVLKQDCERDLAKAIPVLE 2614
            ..|..:..:||:   .|..|:.:.:....||:.:.:||.   |:....:|:    ||.|..|.:.
Mouse  3231 NAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVI---ADKQMSVKE----DLDKVEPAVI 3288

  Fly  2615 DALAALNTLKPADITLVKSMKNPPPVIKLVMAAVCVIKGIPPERIPDPASGKMVQDYWGPSKRLL 2679
            :|..|:.::|...:..|:||.|||..:||.:.::|::.|   |...|          |...:.::
Mouse  3289 EAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLG---ESTTD----------WKQIRSII 3340

  Fly  2680 GEMNFLPGLKEFDKDNIPTEIVKRIHKEFIPNKDFDPKVVAKASSAAKGLCQWIIAMMMYDEVAK 2744
            ...||:|.:..|..:.|...|.:::.|.::.|..::.::|.:||.|...:.:|.||.:.|.::.|
Mouse  3341 MRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLK 3405

  Fly  2745 VVAPKKAKLAGAEKEYADTMEFLAQKRALALALEEKVALLNIELDKANAEMQKTEEHAESCRNKL 2809
            .|.|.:.:|...|.:..|..:...:...:...||..:|....|.....:|.|..:....:...|:
Mouse  3406 RVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKV 3470

  Fly  2810 LRAEALIGGLGGEKSRWNKAAEDLQELYDHLPGDVLISCGIIAYLSAVNLQYRSECVKDWFKKVT 2874
            .|:.||:..|..|:.||.|.:|..:.....:.||.|:|...|||....:.|.|......|...:.
Mouse  3471 NRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQ 3535

  Fly  2875 DLKIPCSSHYSITDVLGLEVTIQNWQLDGLPNDEFSSENAIISANSSRYSLFIDPQAQANNWLKN 2939
            ...|...:..:.|:.|........||...||.|:..:||||:....:||.|.|||..||..::.|
Mouse  3536 QANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMN 3600

  Fly  2940 MERKNRLNCVKFNQSNYMKVIAEALEYGTPVIIENVQEELEVPLDPILMRQTFVQGGIKHISLGE 3004
            ..:..::....|....:.|.:..||.:|.|:::::| |..:..|:|:|.|:....||...|:||:
Mouse  3601 EYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDV-ESYDPVLNPVLNREVRRTGGRVLITLGD 3664

  Fly  3005 SVVPVNPNFRLYMTCNLRNPHFLPETFNKVTVINFALTQNALMDQLLSIVVAKERPDLQELRITL 3069
            ..:.::|:|.::::.......|.|:..::||.:||.:|:::|..|.|:.|:..||||:.|.|..|
Mouse  3665 QDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDL 3729

  Fly  3070 TTEAAANKGALRDAENMILKTLS-AGGDILENEAAIQILADSKGLSKDIVEKQEAAKETVAKIEA 3133
            .......:..||..|..:|:.|: ..|.||:::..|..|.:.|..:.::..|.|.....:.::|.
Mouse  3730 LKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVET 3794

  Fly  3134 FRLNYKPVAVHSSILYYSITDLPNIDPMYQFSLNWYINLY---MYSIETANKSKDLPRRIKFLVD 3195
            ....|.|::...|.:|:::..|..:..:||:||.:::::|   :|.......:.|..:|:..:..
Mouse  3795 VSQQYLPLSTACSSIYFTMESLKQVHFLYQYSLQFFLDIYHNVLYENPNLKGATDHTQRLSIITK 3859

  Fly  3196 GFTRNLYNNVCRSIFEKDKLLYSFILTARILL------GTGQVEMRHF---AHLVTNAKESTNIP 3251
            ...:..:|.|.|.:..:|.:.::.:| |||.|      .|...|.:||   ..:|.:|..:
Mouse  3860 DLFQVAFNRVARGMLHQDHITFAMLL-ARIKLKGTVGEPTYDAEFQHFLRGKEIVLSAGST---- 3919

  Fly  3252 PNPDPTWITETVWLNVLRLEELKELRGIVDHFKS--HLHAWQAIYDHSSPEKQPLPPPWQDKT-- 3312
              |....:|......|:||..|...:.::...::  ....|   .|.|||| |.:|..|.::|
Mouse  3920 --PKIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIW---LDSSSPE-QTVPYLWSEETPT 3978

  Fly  3313 ----TAFEKIIVLKALRPDSVFLAVRLFIAESIGDQYVTPPEFDISKSYADSTAL---TPLVFIL 3370
                .|..::::::|.|||.:.....:|::.::|:.:::..|..:..::...|.:   ||::...
Mouse  3979 TPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCS 4043

  Fly  3371 SPGADPLGSLLAFAEKMGQEETFQ--SISLGQGQG-PIATALIKNAQEMGYWVCLQNCHLAASWM 3432
            .||.|..|.:    |.:..|:..|  ||::|..:| ..|...|..|.:.|.||.|:|.|||..|:
Mouse  4044 VPGYDASGHV----EDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWL 4104

  Fly  3433 PYLEYLWENMDTFNTTPNFRIWLTAYPTPQFPVTILQNGVKMTNEPPTGLKENLMRSYNSEPIND 3497
            ..||   :.:.:......||::||....|:.||.:|:.|.....|||.|:|.|::|:::|.|:
Mouse  4105 MQLE---KKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPV-- 4164

  Fly  3498 YEFYTGCAKQDRAFTRLLYGICFFHAVVQERRKYGPLGWNIAYGFNESDLQISVLQLSMLLNQY- 3561
                :...|......||.:.:.:|||::|||.:|.||||:..|.|.||||:.:...:...|:..
Mouse  4165 ----SRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTA 4225

  Fly  3562 --------DHVPYDAISYLTSECNYGGRVTDNWDRRLIVTILADFCNAQAVTDNRYRFA------ 3612
                    |.:|:.|:..|.::..|||||.:.:|:||:.|.|......::. |:.::.|
Mouse  4226 KGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSF-DSEFKLACKVDGH 4289

  Fly  3613 SDDRYILPRKTEHREILRYLDENLPSLAPPEVYGLHANSGITRDLQTTK--TLLDSMI--LLLGS 3673
            .|.:  :|......|.:::: |.||....|...||..|:  .|.|.||:  .::..|:  .:|..
Mouse  4290 KDIQ--MPDGIRREEFVQWV-ELLPDAQTPSWLGLPNNA--ERVLLTTQGVDMISKMLKMQMLED 4349

  Fly  3674 EAAGSAGAGVSVEQVILDTIKQIEREMPADMD------------IEAAAEKY----PVDYNESMN 3722
            |                |.:...|.|..|..|            :...|..:    |...:....
Mouse  4350 E----------------DDLAYAETEKKARTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSPLKR 4398

  Fly  3723 TV--VVQEMERFL--------KLQKEIRTTCRDLAMGIKGIIVMTPDLENVMTAMKFNRIPTKWM 3777
            ||  :...:.||.        ||.:::|....|:....:|....|..|..::..:....:|..|.
Mouse  4399 TVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWS 4463

  Fly  3778 SKSYPCLKPLGSYVQDLYKRLNWLHDWHHHG--------KPPTFWLSGFFFTQAFLTGAMQNFAR 3834
            ..:.|....:..:|.|..:|:..|.:.....        |.....|.|.|..:|::|...|..|:
Mouse  4464 HYTVPAGMTVIQWVSDFSERIKQLQNISQAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQ 4528

  Fly  3835 KYKIPIDTLTFDYDVLKVETKT-SPPDDGVYCNGLYLEGARWEWRENTLVEQFPKVLIYAMPVIF 3898
            .....::.|..:.:|...::.| .....||  .||.|:||.....:.:|......||
Mouse  4529 ANSWSLEELCLEVNVTASQSATLDACSFGV--TGLKLQGATCSNNKLSLSNAISTVL-------- 4583

  Fly  3899 FRPVGLVDVVEGSRYRCPLYKTAERKGTLSTTGHSTNYVVPLLLN---------------THVKA 3948
              |:        ::.|.....:||:|.::.|        :|:.||               |....
Mouse  4584 --PL--------TQLRWVKQTSAEKKASVVT--------LPVYLNFTRADLIFTVDFEIATKEDP 4630

  Fly  3949 SHWVKRSVALIC 3960
            ..:.:|.||::|
Mouse  4631 RSFYERGVAVLC 4642

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhc62B	NP_995958.2	DHC_N2	678..1102	CDD:285579	105/438 (24%)
		P-loop_NTPase	1239..1469	CDD:304359	121/240 (50%)
		P-loop_NTPase	1553..1699	CDD:304359	61/150 (41%)
		P-loop_NTPase	1874..2145	CDD:304359	75/286 (26%)
		P-loop_NTPase	2249..2511	CDD:304359	71/282 (25%)
		MT	2524..2864	CDD:289543	85/346 (25%)
		AAA_9	2898..3111	CDD:289547	65/213 (31%)
		Dynein_heavy	3253..3952	CDD:281078	180/781 (23%)
Dync1h1	NP_084514.2	Stem. /evidence=ECO:0000250	2..1865		277/1333 (21%)
		DHC_N1	238..830	CDD:285571	14/85 (16%)
		Interaction with DYNC1I2. /evidence=ECO:0000250	446..701
		Interaction with DYNC1LI2. /evidence=ECO:0000250	649..800		9/35 (26%)
		DYN1	1044..4327	CDD:227570	934/3547 (26%)
		DHC_N2	1321..1719	CDD:285579	108/449 (24%)
		P-loop_NTPase	1866..2103	CDD:304359	120/237 (51%)
		AAA 1. /evidence=ECO:0000250	1866..2097		118/231 (51%)
		AAA 2. /evidence=ECO:0000250	2178..2450		84/291 (29%)
		P-loop_NTPase	2217..2357	CDD:304359	61/150 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2388..2408		2/19 (11%)
		AAA 3. /evidence=ECO:0000250	2554..2803		71/262 (27%)
		P-loop_NTPase	2565..2826	CDD:304359	72/274 (26%)
		AAA 4. /evidence=ECO:0000250	2897..3166		68/269 (25%)
		P-loop_NTPase	2907..3185	CDD:304359	70/278 (25%)
		Stalk. /evidence=ECO:0000250	3187..3498		80/330 (24%)
		MT	3199..3530	CDD:289543	85/350 (24%)
		AAA 5. /evidence=ECO:0000250	3551..3780		67/229 (29%)
		AAA_9	3559..3774	CDD:289547	66/215 (31%)
		Dynein_heavy	3920..4630	CDD:281078	180/776 (23%)
		AAA 6. /evidence=ECO:0000250	4003..4219		69/228 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710