Protein Alignment CG8001 and wdtc1

DIOPT Version :10

• Sequence 1: NP_647657.1
• Gene: CG8001 / 38224
• FlyBaseID: FBgn0035268
• Length: 748
• Species: Drosophila melanogaster
• Sequence 2: NP_001124078.1
• Gene: wdtc1 / 570606
• ZFINID: ZDB-GENE-030131-3224
• Length: 674
• Species: Danio rerio
• Alignment Length: 692
• Identity: 147/692 - (21%)
• Similarity: 230/692 - (33%)
• Gaps: 270/692 - (39%)

  Fly   264 MCKCKPKYTWNYDQELLQREHNIINRIDWRGGHTSASSFGQGYYGSRQVVEQMTLLSSLNVHHGC 328
            |..|:.....|...:||.|:..          ...|..|.:.|:.:...::::.|.:.|..|.||
Zfish     1 MTCCETMTLRNITGDLLHRQIR----------ENRALDFQRHYHVTDPFIKRLGLEAELQGHSGC 55

  Fly   329 VNSLNFNRAGDLICSGSDDLTIVVWDWAKEKQLHRFRSGHNMNIFQTKFIDSAGCLDIVSSSRDG 393
            ||.|.:|..|||:.|||||...::||..:..:|....:||..|||..||:..:....:::.:.|.
Zfish    56 VNCLEWNEKGDLLASGSDDQHAIIWDPFRHSKLITMHTGHAANIFSVKFLPHSDDRILITGAADT 120

  Fly   394 QVRRSVIPPSGGVIKPIRLYT-HSESVHKIIVVPHSRHELMSAGEDAAVKHFDLRASNAATTMM- 456
            :|....:...    :.|.::: |:..|.:|...|...:...||.||..::.:|||.|:..:.::
Zfish   121 KVHVHDVTAK----ETIHMFSDHTNRVKRIATAPMWPNTFWSAAEDGLIRQYDLRESSKRSDVLI 181

  Fly   457 ---------------------------------------RCVYN--------------------- 461
                                                   |.::|
Zfish   182 DLTEYCGQLVEAKCLAVNPRDNNYLAVGANGPFVRLYDIRMIHNHRKSLSQSSSAGVHTFCDKRK 246

  Fly   462 --------------------DENERGR------------------------VRLFSIA--HHPYA 480
                                |.|.|.|                        |.||.:.  ..||.
Zfish   247 SIPDGAGQYYVAGHLPVKLPDYNNRLRVLVATYVTFSPDGTELLVNMGGEQVYLFDLTFKQRPYT 311

  Fly   481 ---PEFC--------------------------------VSGSDD----ILRVYDKRNLAKA--- 503
               |:.|                                .|||.|    :.|:..:.|.|.|
Zfish   312 FLLPKKCHSSTDVQNGKTTNGVSNGIHLPASRLKLAKVSSSGSGDLPLHLERIKQRANDAFARQQ 376

  Fly   504 -----------IHQMAP-------------------------RNLLEA----------------- 515
                       ||:..|                         |:.|:|
Zfish   377 WTQAIQLYSLGIHEAGPNAMLYGNRAAAYMKRKWDGDHYDALRDCLKALSLNPGHLKAHFRLARC 441

  Fly   516 -----------------------QITQITCAVYNHSGSEILASYSDA-----GIYLFDSRNYNRG 552
                                   |.....|...:......|.|.:||     |.......|::|.
Zfish   442 LFELKYVAEALECLNDFKGKFPEQAHSSACDALDKDIKAALFSKTDASDDKKGNSSIRFHNFSRK 506

  Fly   553 ---------------DYLHCYKGHINSRT-IKGVNFFGPRSEYIVSGSDCGNIFFWDKNTEAIIN 601
                           ||.|.|.||.|:.| ||..||||.:.:|||||||.|:.|.|:|.|..::.
Zfish   507 ESIPEDEIVLRERSFDYKHRYCGHCNTTTDIKEANFFGSKGQYIVSGSDDGSFFIWEKETTNLVR 571

  Fly   602 YMKGDHVGVVNCLEPHPWMPVLATSGLEHDVKIWTPQGPE-----RKLPEDLLKQTLQRNFRCNI 661
            .::||. .:||||:|||....|||||::..|::|:|: ||     .::.|| ::...|.|.|...
Zfish   572 ILQGDE-SIVNCLQPHPGHCFLATSGIDPVVRLWSPR-PECENENGRVVED-MEGAAQANQRRMN 633

  Fly   662 VESIDLDINNFQYFIRGFLQGSGASHLRQRHTSSLGHQMRDN 703
            .:.:::.:.|..|.|.| |...||....:..:|....|.|.:
Zfish   634 ADPLEVMLLNMGYRISG-LSSRGAEGSDEEDSSEGQVQCRSS 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8001	NP_647657.1	WD40	318..635	CDD:475233	119/563 (21%)
		WD40 repeat	331..367	CDD:293791	13/35 (37%)
		WD40 repeat	373..414	CDD:293791	6/40 (15%)
		WD40 repeat	419..462	CDD:293791	13/123 (11%)
		WD40 repeat	472..513	CDD:293791	17/120 (14%)
		WD40 repeat	520..559	CDD:293791	11/58 (19%)
		WD40 repeat	567..594	CDD:293791	16/26 (62%)
		WD40 repeat	611..657	CDD:293791	20/50 (40%)
wdtc1	NP_001124078.1	WD40	<45..304	CDD:441893	51/262 (19%)
		WD40 repeat	57..93	CDD:293791	14/35 (40%)
		WD40 repeat	99..137	CDD:293791	7/41 (17%)
		WD40 repeat	143..184	CDD:293791	11/40 (28%)
		WD40 repeat	191..218	CDD:293791	0/26 (0%)
		WD40 repeat	238..277	CDD:293791	4/38 (11%)
		WD40 repeat	278..315	CDD:293791	5/36 (14%)
		Spy	358..>504	CDD:443119	18/145 (12%)
		TPR repeat	365..389	CDD:276809	3/23 (13%)
		TPR repeat	394..427	CDD:276809	3/32 (9%)
		TPR repeat	432..456	CDD:276809	0/23 (0%)
		WD40 repeat	534..574	CDD:293791	19/39 (49%)
		WD40	<543..>607	CDD:441893	30/64 (47%)