DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht2 and Chi3l1

DIOPT Version :9

Sequence 1:	NP_001246550.1	Gene:	Cht2 / 38223	FlyBaseID:	FBgn0022702	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_001296749.1	Gene:	Chi3l1 / 89824	RGDID:	620874	Length:	391	Species:	Rattus norvegicus

Alignment Length:	455	Identity:	158/455 - (34%)
Similarity:	230/455 - (50%)	Gaps:	95/455 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTLRSRLSGEAPQLWLLLLLASTASSLWASVAARTGPLHDKVVVCYVSTWAVYRPEQGAYAIENF 65
            |.:|..|:|.|.   |:||.:.:|..|                |||.:.|:.||...|:...:..
  Rat     9 MGMRVALTGFAV---LMLLQSCSAYKL----------------VCYYTNWSQYREGNGSCFPDAL 54

  Fly    66 DPNLCTHVVYAFAGLDITQAAIKSLDPWQDLKEEYGKGGYEKMTGLKRSHPHLKVSLAIGGWNEG 130
            |.:||||::|:||.:...:.   |...|.|:..      |..:..||..:|.||..|::|||:.|
  Rat    55 DHSLCTHIIYSFANISNNKL---STSEWNDVTL------YGMLNTLKTRNPRLKTLLSVGGWSFG 110

  Fly   131 SANYSTLVANNLLRGRFVKQVSSFIRKYNFDGLDLDWEYPTQRKGKPADRENFVLLTKELREEFD 195
            |..:|.:|:|...|..||:.|:.|:|.|.||||||.|.||     .|.|:::|..|.|||:.||.
  Rat   111 SERFSRIVSNAKSRKTFVQSVAPFLRTYGFDGLDLAWLYP-----GPKDKQHFTTLIKELKAEFT 170

  Fly   196 E------HGLLLTSAIGASKKVIDEAYDVRQISRYLDYLHIMCYDYHGSWDRRVGYNAPL----- 249
            :      ..|||::|:.|.|..:|..|||.||:::||::::|.||:||:|....|:::||
  Rat   171 KEVQPGTEKLLLSAAVSAGKVTLDSGYDVAQIAQHLDFINLMTYDFHGTWRHTTGHHSPLFRGQQ 235

  Fly   250 -TAPADDPLSVKFSIDYLLKLGAPPEKLVMGLPFYGRTFKTLASGFLNDVS---EGVGFKGPYTR 310
             |.| |...:|.:.:.|:|:||||..|||||:|.:|::| ||||. .|.|.   .|.|..|.||:
  Rat   236 DTGP-DRFSNVDYGVGYMLRLGAPTNKLVMGIPTFGKSF-TLASS-ENQVGAPITGSGLPGRYTK 297

  Fly   311 EDGFLGYNEICQTLSNQTSGWTREWDPQTSQVLAKSERNVFTQEINVVT-------YDSSRSIAN 368
            |.|.|.|.|||..|..                 |:..| :..|::...|       ||...|:.|
  Rat   298 EKGTLAYYEICDFLRG-----------------AEVHR-ILGQQVPFATKGNQWVGYDDPESVKN 344

  Fly   369 KVLFAMSKRLAGVMVWSVDTDDFLGN-CKLDEDTYEDFQKVTAAPKRSSQNYPLLRTINEATMLA 432
            ||.:..:|:|||.|||:||.|||.|: |                  ..:.::||...|.||..:|
  Rat   345 KVKYLKNKQLAGAMVWAVDLDDFRGSFC------------------GHNVHFPLTNAIKEALAVA 391

Fly 433 432
Rat 392 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht2	NP_001246550.1	Glyco_18	42..389	CDD:214753	137/368 (37%)
Cht2	NP_001246550.1	GH18_chitolectin_chitotriosidase	43..428	CDD:119351	145/407 (36%)
Chi3l1	NP_001296749.1	Glyco_18	31..365	CDD:214753	138/384 (36%)
Chi3l1	NP_001296749.1	GH18_chitolectin_chitotriosidase	32..388	CDD:119351	147/424 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58170
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920