DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht2 and Cht4

DIOPT Version :9

Sequence 1:	NP_001246550.1	Gene:	Cht2 / 38223	FlyBaseID:	FBgn0022702	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster

Alignment Length:	427	Identity:	166/427 - (38%)
Similarity:	234/427 - (54%)	Gaps:	74/427 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LW----LLLLLASTASSLWASVAARTGPLHDKVVVCYVSTWAVYRPEQGAYAIENFDPNLCTHVV 74
            :|    |.|.|...|||             :|::.||..|||.|||..|.:...:.||:||||:.
  Fly     6 IWALAALCLCLGQVASS-------------EKLLNCYWGTWANYRPGDGKFTPSDIDPSLCTHIS 57

  Fly    75 YAFAGLDITQAAIKSLDPWQDLKEEYGKGGYEKMTGLKRSHPHLKVSLAIGGWNEGSANYSTLVA 139
            |.|.|:. .....||||.|.|:.:  |.|...:...||:.:|:||:...:|||||||..||.:.|
  Fly    58 YTFFGIS-DAGEFKSLDTWLDMDD--GLGFISQTIALKQRNPNLKILAVVGGWNEGSTKYSAMAA 119

  Fly   140 NNLLRGRFVKQVSSFIRKYNFDGLDLDWEYPTQRKGKPADRENFVLLTKELREEFDEHGLLLTSA 204
            :...|..||....:||::|:|||||||||||.||.|..|||||||.|.:|::|.:|::||.|..|
  Fly   120 DPAKRATFVSTSLAFIQQYSFDGLDLDWEYPGQRGGSEADRENFVTLLREIKETYDQYGLELGIA 184

  Fly   205 IGASKKVIDEAYDVRQISRYLDYLHIMCYDYHGSWDRRVGYNAPLTAPADDPLSVKFSIDYLLKL 269
            :|||:|....:||:..||::|.::::|.||:|.:.|..:|.||||...|:       ||||.|..
  Fly   185 VGASEKSASISYDIPAISQHLTFINVMTYDFHMALDGYLGLNAPLPEVAE-------SIDYWLSH 242

  Fly   270 GAPPEKLVMGLPFYGRTFKTLASGFLNDVSE--------GVGFKGPYTREDGFLGYNEICQTLSN 326
            |||.|||::|:.|||.:::      ::|.|:        |.|..|.||||:|||||:|||  |:|
  Fly   243 GAPAEKLILGIGFYGHSYQ------MSDSSQNWPGAACIGPGTAGVYTRENGFLGYHEIC--LNN 299

  Fly   327 QTSGWTREWDPQTSQVLAKSERNVFTQEINVVTYDSSRSIANKVLFAMSKRLAGVMVWSVDTDDF 391
                |...:|.:.....|       .|....:.||:..||..|:....|:.|.|.|:||::||||
  Fly   300 ----WQTVFDQENGAPYA-------FQGDQWIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDF 353

  Fly   392 LGNCKLDEDTYEDFQKVTAAPKRSSQNYPLLRTINEA 428
            .|.|                    .::||||:|:|.|
  Fly   354 RGLC--------------------GESYPLLKTMNRA 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht2	NP_001246550.1	Glyco_18	42..389	CDD:214753	145/354 (41%)
Cht2	NP_001246550.1	GH18_chitolectin_chitotriosidase	43..428	CDD:119351	157/392 (40%)
Cht4	NP_524962.2	GH18_chitolectin_chitotriosidase	26..371	CDD:119351	158/394 (40%)
		Glyco_18	28..351	CDD:214753	145/351 (41%)
		CBM_14	421..462	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	188	1.000	Domainoid score	I962
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I1632
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D48394at33392
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	1	1.000	-	-		mtm1002
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	9	8.970