DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht2 and chia.1

DIOPT Version :9

Sequence 1:	NP_001246550.1	Gene:	Cht2 / 38223	FlyBaseID:	FBgn0022702	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_998215.1	Gene:	chia.1 / 406323	ZFINID:	ZDB-GENE-040426-1994	Length:	455	Species:	Danio rerio

Alignment Length:	452	Identity:	141/452 - (31%)
Similarity:	208/452 - (46%)	Gaps:	84/452 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LLLLASTASSLWASVAARTGPLHDKVVVCYVSTWAVYRPEQGAYAIENFDPNLCTHVVYAFAGLD 81
            |.:||.....|...:.:.|      .:|||::.|:.|||..|.:..||.||.||||||||.|.:.
Zfish     4 LTILAGLGILLSLQIVSST------KLVCYMTNWSQYRPGNGKFLPENIDPFLCTHVVYALATIS 62

  Fly    82 ITQAAIKSLDPWQDLKEEYGKGGYEKMTGLKRSHPHLKVSLAIGGWNEGSANYSTLVANNLLRGR 146
            ... .|.::: |.|:..      |:.|..||:.:|.||..|::||...|.:.|..:||....|..
Zfish    63 YDN-QITTIE-WNDVDL------YKSMNELKKVNPALKTQLSVGGLVNGVSPYINMVATPENRKA 119

  Fly   147 FVKQVSSFIRKYNFDGLDLDWEYPTQRKGKPADRENFVLLTKELREEFDEHG-------LLLTSA 204
            |::....|:|.:.|||:|:||:||......|.|::......||:|:..::..       |||:..
Zfish   120 FIRNALLFLRLHEFDGMDIDWQYPGHNGSPPQDKQRLTTFIKEMRDAIEQEAIDTKKTPLLLSIK 184

  Fly   205 IGASKKVIDEAYDVRQISRYLDYLHIMCYDYHGSWDRRVGYNAPLTAPADDPLS-----VKFSID 264
            :.|.|..|:.||:.::::..:|::.||.|||||.||...|:|:||...:.|..|     :..|::
Zfish   185 VSAIKTTIENAYEAKEVASLVDFVTIMSYDYHGHWDPITGHNSPLFRSSFDTGSIVHHNINSSLE 249

  Fly   265 YLLKLGAPPEKLVMGLPFYGRTF--KTLASGFLNDVSEGVGFKGPYTREDGFLGYNEICQTLSNQ 327
            :.|..|||.::|::|||.|||||  .|..:| |...:.|....||||||.||..|.|||...|:.
Zfish   250 FWLGSGAPADRLLLGLPTYGRTFMLSTSQTG-LGAPANGPADAGPYTREAGFWSYYEICPMESSV 313

  Fly   328 TSGWT-----------REWDPQTSQVLAKSERNVFTQEINVVTYDSSRSIANKVLFAMSKRLAGV 381
            ...|.           |.|                      |.:|:..||..||.:..|.:|.|.
Zfish   314 PIHWIDEQMVPYAVQGRAW----------------------VGFDNQESITAKVQWLNSLKLGGA 356

  Fly   382 MVWSVDTDDFLGNCKLDEDTYEDFQKVTAAPKRSSQN--YPLLRTINEATMLAVDELAVPEP 441
            .||::|.|||.|                    |...|  |||:..:..:..........|.|
Zfish   357 SVWTLDFDDFAG--------------------RFCYNGAYPLVNHLRNSLGFPPKPTTTPRP 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht2	NP_001246550.1	Glyco_18	42..389	CDD:214753	125/371 (34%)
Cht2	NP_001246550.1	GH18_chitolectin_chitotriosidase	43..428	CDD:119351	134/411 (33%)
chia.1	NP_998215.1	Glyco_18	23..364	CDD:214753	125/371 (34%)
		GH18_chitolectin_chitotriosidase	24..386	CDD:119351	134/412 (33%)
		ChtBD2	407..455	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58170
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920