DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht2 and Idgf6

DIOPT Version :9

Sequence 1:	NP_001246550.1	Gene:	Cht2 / 38223	FlyBaseID:	FBgn0022702	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster

Alignment Length:	485	Identity:	113/485 - (23%)
Similarity:	201/485 - (41%)	Gaps:	115/485 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LLLLLASTASSLWASVAARTG--PLHDKVVVCYVSTWAVYRPEQGAYAIENFDPNL--CTHVVYA 76
            ::..||..:..|.:..|::.|  .|..|.:|||..:.:..:...|...|:..:|.|  |.::||.
  Fly     2 IIKALAIVSLCLASIQASKVGAPQLPKKHLVCYYDSASFVKEGLGKLVIDELEPALQFCDYLVYG 66

  Fly    77 FAGLDITQAAIKSLDPWQDLKEEYGKGGYEKMTGLKRSHPHLKVSLAIGG---------WNEGSA 132
            :||::.......||:  |.|..:.|||.|..:|.|||.:|::|:.|::||         ..|...
  Fly    67 YAGIERDSHKAVSLN--QQLDLDLGKGLYRTVTRLKRKYPNVKILLSVGGDKDIELDKDAKELPN 129

  Fly   133 NYSTLVANNLLRGRFVKQVSSFIRKYNFDGLDLDWEYPTQRKGKP-------------------- 177
            .|..|:.:...|.|||..|.|.::.|.|||||:.|::|   |.||
  Fly   130 KYLELLESPTGRTRFVNTVYSLVKTYGFDGLDVAWQFP---KNKPKKVHSGIGSLWKGFKKVFSG 191

  Fly   178 ---------ADRENFVLLTKELREEFDEHGLLLTSAI--GASKKVIDEAYDVRQISRYLDYLHIM 231
                     ..:|.|..|.::::..|....|||::.:  ..:..:.   ||:..:..|||::::.
  Fly   192 DSIVDEKSEEHKEQFTALLRDVKNAFRPDNLLLSTTVLPNVNSSLF---YDIPAVVNYLDFVNLG 253

  Fly   232 CYDYHGSWDRR---VGYNAPL--TAPADDPLSVKFSIDYLLKLGAPPEKLVMGLPFYGRTFKTLA 291
            .:|:. :..|.   ..|.||:  .:..:...:|...:.|.|:...|..|:.:|:..|||.:|
  Fly   254 TFDFF-TPQRNPEVADYAAPIYELSERNPEFNVAAQVKYWLRNNCPASKINVGVATYGRPWK--- 314

  Fly   292 SGFLNDVSEGVGFK-----------GPYTREDGFLGYNEICQTLSNQTSGWTREWDPQTSQVL-- 343
               |.|.|...|..           |..|:..|...:.|:|..|.||.:.:.:..:....:|.
  Fly   315 ---LTDDSGDTGVPPVKDVKDEAPVGGNTQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDP 376

  Fly   344 -------------AKSERNVFTQEINVVTYDSSRSIANKVLFAMSKRLAGVMVWSVDTDDFLGNC 395
                         .|.:..::      |:::...:.|:|..:..::.|.||.::.:..|||.|.|
  Fly   377 AKRFGSYAYRAADKKGDNGIW------VSFEDPDTAADKAGYVRTENLGGVALFDLSYDDFRGLC 435

  Fly   396 KLDEDTYEDFQKVTAAPKRSSQNYPLLRTI 425
                               :::.||:||.|
  Fly   436 -------------------TNEKYPILRAI 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht2	NP_001246550.1	Glyco_18	42..389	CDD:214753	96/419 (23%)
Cht2	NP_001246550.1	GH18_chitolectin_chitotriosidase	43..428	CDD:119351	106/456 (23%)
Idgf6	NP_001286499.1	GH18_IDGF	30..450	CDD:119352	106/457 (23%)
Idgf6	NP_001286499.1	Glyco_18	31..429	CDD:214753	96/418 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I1336
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	5	4.960