DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht2 and Idgf1

DIOPT Version :9

Sequence 1:	NP_001246550.1	Gene:	Cht2 / 38223	FlyBaseID:	FBgn0022702	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_477258.1	Gene:	Idgf1 / 34978	FlyBaseID:	FBgn0020416	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	485	Identity:	120/485 - (24%)
Similarity:	193/485 - (39%)	Gaps:	126/485 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 QLWLLLLLASTASSLWASVAARTGPLHDKVVVCYVSTWAVYRPEQGAYAIENFDPNL----CTHV 73
            ||:.:|.|.|..|...|:          ..::||..:.:..|  ||...:...:.:|    |||:
  Fly     4 QLFYILGLLSVTSLTHAA----------SNLICYYDSNSYLR--QGLAKMHTNELDLALQFCTHL 56

  Fly    74 VYAFAGLDITQAAIKSLDPWQDLKEEYGKGGYEKMTGLKRSHPHLKVSLAIGG---WNEGSAN-- 133
            ||.:|||......:.||:  .||...|    |:.:|.|::..|.||:.|::||   .:|...|
  Fly    57 VYGYAGLKSGTLELFSLN--VDLDMFY----YKDITALRQKFPQLKILLSVGGDRDVDEAHPNKY 115

  Fly   134 YSTLVANNLLRGRFVKQVSSFIRKYNFDGLDLDWEYPTQRKGKPADRENFV---------LLTKE 189
            ...|.||...:..|:......:::..||||||.::.|   :.||......:         |.|.:
  Fly   116 VELLEANRTAQQNFIDSSMILLKRNGFDGLDLAFQLP---RNKPRKVHGSLGSYWKSFKKLFTGD 177

  Fly   190 --LREEFDEHGLLLTSAIGASKKVIDEA-----------------YDVRQISRYLDYLHIMCYDY 235
              :..:.:||....|..:|..|.....|                 :||.::....||:::..:|:
  Fly   178 FVVDPQAEEHKSQFTDLVGNIKNAFRSANLMLSLTVLPNVNSTWYFDVPKLHPQFDYINLAAFDF 242

  Fly   236 HGSWDRRVGYNAPLTAP---ADDP-----LSVKFSIDYLLKLGAPPEKLVMGLPFYGRTFKTLAS 292
              ....|....|..|||   .|:.     |:|:|.|:|.|:...|.:||.:|:..|||.:|
  Fly   243 --LTPLRNPEEADFTAPIFFQDEQNRLPHLNVEFQINYWLQNHCPGQKLNLGIASYGRAWK---- 301

  Fly   293 GFLNDVSEGVGFKG-PYTRE--------------DGFLGYNEICQTLSNQTSGWTR-EWDP---- 337
                 :|:|.|..| |...|              :|.|.:.|||..||...|...| |..|
  Fly   302 -----LSKGSGLSGAPIVHETCGVAPGGIQIQSAEGLLSWPEICSKLSQNASAQYRGELAPLRKV 361

  Fly   338 ------QTSQVLAKSERNVFTQEINV-VTYDSSRSIANKVLFAMSKRLAGVMVWSVDTDDFLGNC 395
                  ..:..|..::.|   .:..| :::|.......|.::|..|.|.|:.::.:..|||.|.|
  Fly   362 TDLTQKYGNYALRPADDN---GDFGVWLSFDDPDFAGIKAVYAKGKGLGGIALFDLSYDDFRGLC 423

  Fly   396 KLDEDTYEDFQKVTAAPKRSSQNYPLLRTI 425
                               :.|.||:||:|
  Fly   424 -------------------TGQKYPILRSI 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht2	NP_001246550.1	Glyco_18	42..389	CDD:214753	102/418 (24%)
Cht2	NP_001246550.1	GH18_chitolectin_chitotriosidase	43..428	CDD:119351	113/455 (25%)
Idgf1	NP_477258.1	GH18_IDGF	23..438	CDD:119352	113/456 (25%)
Idgf1	NP_477258.1	Glyco_18	24..417	CDD:214753	102/417 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910