DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht2 and Cht12

DIOPT Version :9

Sequence 1:	NP_001246550.1	Gene:	Cht2 / 38223	FlyBaseID:	FBgn0022702	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_726022.1	Gene:	Cht12 / 246535	FlyBaseID:	FBgn0050293	Length:	470	Species:	Drosophila melanogaster

Alignment Length:	395	Identity:	121/395 - (30%)
Similarity:	188/395 - (47%)	Gaps:	54/395 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 VVCYVSTWAVYRPEQGAYAIENFDPNLCTHVVYAFA-GLDITQAAIKSLDPWQDLKEEYGKGGYE 106
            |.|.....:.|...:..:...:.|..||||:|.... |:|.....::..|....|::       :
  Fly    25 VFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLGSGIGVDGDSGELRITDKILLLEK-------D 82

  Fly   107 KMTGLK--RSHPHLKVSLAIGGWNEGSANYSTLVANNLLRGRFVKQVSSFIRKYNFDGLDLDWEY 169
            |::.:|  :.....||...||||.|.|:::|.:||:...|..|...:..|:.::.|||:.:||.|
  Fly    83 KLSSVKTMKWDSIKKVMFTIGGWEEDSSSFSRMVASPKKRDNFYSSMLEFMFRWGFDGVQIDWRY 147

  Fly   170 PTQRKGKPADRENFVLLTKELREEFDEHGLLLTSAI-GASKKVIDEAYDVRQISRYLDYLHIMCY 233
            ||...|.|.||:|||:|.:||...|.::.|:|..|: |.....|.|:|::.:|..:.|::|:|.:
  Fly   148 PTLLGGHPDDRQNFVILLEELGLIFRKNQLILMVAVLGRRDNRILESYNIPEIVNHSDFIHLMMH 212

  Fly   234 DYHGSWDRRVGYNAPLTAPADDPLSVKFSIDYLLKLGAPPEKLVMGLPFYGRTFKTLASGFLNDV 298
            |....:..|:.|||||.....   ||..||.:..:.|..||||::|:|.:.|:| |:..   |..
  Fly   213 DEQDPYHLRLAYNAPLVGYEG---SVTDSIMHWKRNGGAPEKLILGIPLFVRSF-TMDR---NQS 270

  Fly   299 SEGVGFKGP-----YTREDGFLGYNEICQTLSNQTSGWTREWDPQTSQVLAKSERNVFTQEINVV 358
            :.|...|||     .:...||:.|||.|.    |.|.|:|.:|.     |||..  ..|:....|
  Fly   271 TVGSACKGPGRQTKQSHRPGFMTYNEWCV----QQSKWSRMFDQ-----LAKVP--YATRGDQWV 324

  Fly   359 TYDSSRSIANKVLFAMSKRLAGVMVWSVDTDDFLGNCKLDEDTYEDFQKVTAAPKRSSQNYPLLR 423
            :|::.|||..|:......:|.|.|.|::|.|||.|.|                    .:.:.|||
  Fly   325 SYENPRSIWAKMHLLQEHKLGGAMAWTIDVDDFRGRC--------------------GEQHGLLR 369

  Fly   424 TINEA 428
            .|..|
  Fly   370 VIFSA 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht2	NP_001246550.1	Glyco_18	42..389	CDD:214753	111/354 (31%)
Cht2	NP_001246550.1	GH18_chitolectin_chitotriosidase	43..428	CDD:119351	120/393 (31%)
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:299167	121/395 (31%)
		Glyco_hydro_18	47..355	CDD:279094	108/332 (33%)
		ChtBD2	394..438	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I1632
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	1	1.000	-	-		otm46727
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	7	6.960