DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht2 and cht-1

DIOPT Version :9

Sequence 1:	NP_001246550.1	Gene:	Cht2 / 38223	FlyBaseID:	FBgn0022702	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_508588.1	Gene:	cht-1 / 180628	WormBaseID:	WBGene00000503	Length:	617	Species:	Caenorhabditis elegans

Alignment Length:	407	Identity:	129/407 - (31%)
Similarity:	205/407 - (50%)	Gaps:	46/407 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 ARTGPLHDKVVVCYVSTWAVYRPEQGAYAIENFDPNLCTHVVYAFAGLDITQAAIKSLDPWQDLK 97
            ||:.|.:..:..||.:.||.||..:..:..|::.|.||||:::||..:: ....:::.|| .||.
Worm    45 ARSEPTNSYIRPCYFTNWAQYRQGRAKFVPEDYTPGLCTHILFAFGWMN-ADYTVRAYDP-ADLP 107

  Fly    98 EEY-GKGGYEKMTGLKRSHPHLKVSLAIGGWNEGSANYSTLVANNLLRGRFVKQVSSFIRKYNFD 161
            .:: |:|.|.::..||.:...||..|:.|||:.|:|.:..:.|::..|..|:....:|:|.:.||
Worm   108 NDWAGEGMYRRVNKLKVTDTQLKTLLSFGGWSFGTALFQGMAASSASRKVFIDSAITFVRTWGFD 172

  Fly   162 GLDLDWEYPTQRKGKPADRENFVLLTKELREEFDEHG-------LLLTSAIGASKKVIDEAYDVR 219
            |:|:|||||:    ...|..|:|.|.|||:...:...       ||:|:|:.|....||..||:.
Worm   173 GIDIDWEYPS----GATDMANYVALVKELKAACESEAGSTGKDRLLVTAAVAAGPATIDAGYDIP 233

  Fly   220 QISRYLDYLHIMCYDYHGSWDRRVGYNAPLTAPADDPL-----SVKFSIDYLLKLGAPPEKLVMG 279
            .::...|::.:|.||:.|:|...||:|:||.|..:.|.     :|..|..|..:.|.|.||:::|
Worm   234 NLAPNFDFILLMSYDFFGAWASLVGFNSPLYATTELPAEWNGWNVDSSARYWNQKGMPKEKIIVG 298

  Fly   280 LPFYGRTFKTLASGFLNDVSEGVGFK-GPYTREDGFLGYNEICQTLSNQTSGWTREWDPQTSQVL 343
            :|.|||.:....:..:|..:.|...| ..|.:|.|...|.|.|:.|:|   |.||.||.| |||.
Worm   299 MPTYGRGWTLNNASAINPGTSGSPAKITQYVQEAGVGAYFEFCEMLAN---GATRYWDSQ-SQVP 359

  Fly   344 AKSERNVFTQEINVVTYDSSRSIANKVLFAMSKRLAGVMVWSVDTDDFLGNCKLDEDTYEDFQKV 408
            ...:.|.:.      :||...|.|||:.:...:...|..||::|.|||...|.
Worm   360 YLVQGNQWW------SYDDEESFANKMAYVKREGYGGAFVWTLDFDDFNAGCS------------ 406

  Fly   409 TAAPKRSSQNYPLLRTI 425
                ..:.|.|||:..|
Worm   407 ----NSNGQLYPLISVI 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht2	NP_001246550.1	Glyco_18	42..389	CDD:214753	117/360 (33%)
Cht2	NP_001246550.1	GH18_chitolectin_chitotriosidase	43..428	CDD:119351	126/397 (32%)
cht-1	NP_508588.1	GH18_chitolectin_chitotriosidase	55..423	CDD:119351	126/397 (32%)
		Glyco_18	57..399	CDD:214753	117/357 (33%)
		CBM_14	481..532	CDD:279884
		CBM_14	567..615	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910