DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht2 and cht-3

DIOPT Version :9

Sequence 1:	NP_001246550.1	Gene:	Cht2 / 38223	FlyBaseID:	FBgn0022702	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_501082.2	Gene:	cht-3 / 177464	WormBaseID:	WBGene00016084	Length:	1067	Species:	Caenorhabditis elegans

Alignment Length:	429	Identity:	82/429 - (19%)
Similarity:	158/429 - (36%)	Gaps:	124/429 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 VCYVSTWAVYRPE--QGAYAIENFDPNLCTHVVYAFAGLDIT---------QAAIKSLDPWQDLK 97
            :||:.      ||  :..:.|:|...:.|:|:|..:..||::         :..:|.:|.|:...
Worm   375 LCYLD------PEEVEETFPIDNLKSDYCSHIVVPYFALDLSDKMIEEDKAEDLVKKIDDWRSKI 433

  Fly    98 EEYGKGGYEKMTGLKRSHPHLKVSLAIGGWNEGSANYSTLVANNLLRGRFVKQVSSFIRKYNFDG 162
            .|..              |.|.:|:   |..:.|..:..|:.|:..|....:.:...|...|.||
Worm   434 VEVA--------------PRLILSV---GSKQASTIWQFLLGNDFHRKELAEGLVKAINSTNADG 481

  Fly   163 LDLDWEYPTQRKGKPADRENFVLLTKELREEFDEHGL--LLTSAIGA-SKKVIDEAYDVRQISRY 224
            |::.|                  .::.:..:||:..|  .:...:.| :.|:::......|.|.|
Worm   482 LEISW------------------TSQPMVSDFDKKNLKSFINDIVAADTAKMVEIVVATSQQSAY 528

  Fly   225 LDYLHIMCYDY-----------------HGSWDRRVGYNAPLTAPA---DDPLSVKFSIDYLLKL 269
            .|:     |||                 |.......|:.:||.|.:   :..:|.:..:.:.::.
Worm   529 SDF-----YDYEHLNKTASLIVLHSHRLHSDSLPFTGHPSPLRATSSMTNQKMSWESLLSHWVEK 588

  Fly   270 GAPPEKLVMGLPFYGRTFKTLASGFLNDVSEGVGFKGPY----------TREDGFLGYNEICQTL 324
            ...|.|||:.|     :..||:...|.||.....  .|:          :::.......|||::|
Worm   589 RVLPSKLVLSL-----SASTLSMQSLADVRSSAA--TPFGQSAFVSMLRSKKGDIHSQQEICESL 646

  Fly   325 SNQTSGWTREWDPQTSQVLAKSERNVFTQEINVVTYDSSRSIANKVLFAMSKRLAGVMVWSVDTD 389
            .:.| |.|...|......|.:.::        :|.|:::||...|.::|..:.:.|:.:.::..|
Worm   647 KSGT-GVTHWVDGAEVPYLRRYDQ--------MVAYENTRSAHIKAVWASMEGVGGLALHNMHQD 702

  Fly   390 DFLGNCKLDEDTYEDFQKVTAAPKRSSQNYPLLRTINEA 428
            |....|  |..|                .:|:|..::.|
Worm   703 DPSAVC--DNRT----------------AFPILNALSRA 723

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht2	NP_001246550.1	Glyco_18	42..389	CDD:214753	74/388 (19%)
Cht2	NP_001246550.1	GH18_chitolectin_chitotriosidase	43..428	CDD:119351	81/427 (19%)
cht-3	NP_501082.2	Glyco_18	51..334	CDD:214753
		GH18_chitinase-like	51..>103	CDD:299167
		Glyco_18	375..702	CDD:214753	74/388 (19%)
		GH18_chitinase-like	387..723	CDD:299167	77/409 (19%)
		Glyco_hydro_18	761..1043	CDD:279094
		GH18_chitinase-like	<1018..1062	CDD:299167
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810