Protein Alignment Cht2 and CHI3L1

DIOPT Version :10

• Sequence 1: NP_477298.2
• Gene: Cht2 / 38223
• FlyBaseID: FBgn0022702
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: XP_047298796.1
• Gene: CHI3L1 / 1116
• HGNCID: 1932
• Length: 389
• Species: Homo sapiens
• Alignment Length: 414
• Identity: 142/414 - (34%)
• Similarity: 213/414 - (51%)
• Gaps: 80/414 - (19%)

  Fly    43 VVCYVSTWAVYRPEQGAYAIENFDPNLCTHVVYAFAGLDITQAAIKSLDPWQDLKEEYGKGGYEK 107
            :|||.::|:.||...|:...:..|..||||::|:||  :|:...|.:.: |.|:..      |..
Human    24 LVCYYTSWSQYREGDGSCFPDALDRFLCTHIIYSFA--NISNDHIDTWE-WNDVTL------YGM 79

  Fly   108 MTGLKRSHPHLKVSLAIGGWNEGS------ANYSTLVANNLLRGRFVKQVSSFIRKYNFDGLDLD 166
            :..||..:|:||..|::||||.||      ..:|.:.:|...|..|:|.|..|:|.:.||||||.
Human    80 LNTLKNRNPNLKTLLSVGGWNFGSQRADFGPRFSKIASNTQSRRTFIKSVPPFLRTHGFDGLDLA 144

  Fly   167 WEYPTQRKGKPADRENFVLLTKELREEFDEHG------LLLTSAIGASKKVIDEAYDVRQISRYL 225
            |.||.:|     |:::|..|.||::.||.:..      |||::|:.|.|..||.:||:.:||::|
Human   145 WLYPGRR-----DKQHFTTLIKEMKAEFIKEAQPGKKQLLLSAALSAGKVTIDSSYDIAKISQHL 204

  Fly   226 DYLHIMCYDYHGSWDRRVGYNAPLTAPADDPLSVKFS-----IDYLLKLGAPPEKLVMGLPFYGR 285
            |::.||.||:||:|....|:::||....:|....:||     :.|:|:||||..|||||:|.:||
Human   205 DFISIMTYDFHGAWRGTTGHHSPLFRGQEDASPDRFSNTDYAVGYMLRLGAPASKLVMGIPTFGR 269

  Fly   286 TFKTLAS---GFLNDVSEGVGFKGPYTREDGFLGYNEICQTLSNQTSGWTREWDPQTSQVLAKSE 347
            :| ||||   |....:| |.|..|.:|:|.|.|.|.|||..|...|                  .
Human   270 SF-TLASSETGVGAPIS-GPGIPGRFTKEAGTLAYYEICDFLRGAT------------------V 314

  Fly   348 RNVFTQEINVVT-------YDSSRSIANKVLFAMSKRLAGVMVWSVDTDDFLGN-CKLDEDTYED 404
            ..:..|::...|       ||...|:.:||.:...::|||.|||::|.|||.|: |..|
Human   315 HRILGQQVPYATKGNQWVGYDDQESVKSKVQYLKDRQLAGAMVWALDLDDFQGSFCGQD------ 373

  Fly   405 FQKVTAAPKRSSQNYPLLRTINEA 428
                        ..:||...|.:|
Human   374 ------------LRFPLTNAIKDA 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cht2	NP_477298.2	GH18_chitolectin_chitotriosidase	43..428	CDD:119351	141/412 (34%)
CHI3L1	XP_047298796.1	GH18_chitolectin_chitotriosidase	24..386	CDD:119351	142/414 (34%)