Protein Alignment Gk2 and lsrK

DIOPT Version :10

• Sequence 1: NP_647655.1
• Gene: Gk2 / 38221
• FlyBaseID: FBgn0035266
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_416028.3
• Gene: lsrK / 946069
• ECOCYCID: G6798
• Length: 530
• Species: Escherichia coli
• Alignment Length: 549
• Identity: 128/549 - (23%)
• Similarity: 217/549 - (39%)
• Gaps: 99/549 - (18%)

  Fly    36 IDEGTKTIGFSIYTTPDFKEIAAHRVELSVITPQDGWYEQDPLEMMASINK---CAEEAIKQ-LP 96
            :|.||.:|...|:.. :..:||..:.|...:...|     .|..|...:||   .|.|.::| |.
E. coli    17 LDAGTGSIRAVIFDL-EGNQIAVGQAEWRHLAVPD-----VPGSMEFDLNKNWQLACECMRQALH 75

  Fly    97 EQGFSASDIVTVGITNQRETTIVWDAVTGKPLYN---ALLWK----DIRTSTTVEQIVAKVQDPN 154
            ..|.:...|..|...:.||         |..|||   |.:|.    |.|.:..|.::  |....|
E. coli    76 NAGIAPEYIAAVSACSMRE---------GIVLYNNEGAPIWACANVDARAAREVSEL--KELHNN 129

  Fly   155 HFRS----STGLPISTYFSAL-KIRWLRDNVPEVRQAIRERRCKAGTVDSWIVWNLTNGALHITD 214
            .|.:    :||..::  .||: ::.||..:    |..|..:......:..|:.:.| :|.|.: |
E. coli   130 TFENEVYRATGQTLA--LSAIPRLLWLAHH----RSDIYRQASTITMISDWLAYML-SGELAV-D 186

  Fly   215 VTNASRTLLMNLETQAWDPVLLKTFGIREEMLPTIHSCSEIFGKITSERSPLRGM------TLSG 273
            .:||..|.|::|.|:.|.|.||...|:|.::|..:.....:.|.::|:.:.|.|:      .:.|
E. coli   187 PSNAGTTGLLDLTTRDWKPALLDMAGLRADILSPVKETGTLLGVVSSQAAELCGLKAGTPVVVGG 251

  Fly   274 IMGNQQASLLGQMCVKPGQTKNTYRSGCFLLCNTGDKPVFSRHGLLT--TVAYKLGPQA-PTIYA 335
              |:.|...||...|:|.||.        :|..|..:.|.:....:|  .:..::.|.. |.:..
E. coli   252 --GDVQLGCLGLGVVRPAQTA--------VLGGTFWQQVVNLAAPVTDPEMNVRVNPHVIPGMVQ 306

  Fly   336 IEGAVSVAGHALSWLQN----KVRILPDSRDAEKY------AEMVPTSGDVYFVPAFTG-LYAPY 389
            .|......|..:.|.::    :.:::.:....:.|      |..|| .|....:|.|:. :....
E. coli   307 AESISFFTGLTMRWFRDAFCAEEKLIAERLGIDTYTLLEEMASRVP-PGSWGVMPIFSDRMRFKT 370

  Fly   390 WRQNARGIIIGLT---QFTRKNHIVRAALESICFQTRDILECMHQECGYEINKLHAD-----GKL 446
            | .:|....|.|:   ....|..:.||..|:...    :..|..|:.. :.:.:|..     |..
E. coli   371 W-YHAAPSFINLSIDPDKCNKATLFRALEENAAI----VSACNLQQIA-DFSNIHPSSLVFAGGG 429

  Fly   447 TTNNLLMQLQADTIGMPVFRSQLMDSTAFGAAMCAAQADGVNLCQFEPEKRY--YENVHYDTFLA 509
            :...|..|:.||..|:||....:.::||.|.|:.|....|:.....|..:|.  :|..|
E. coli   430 SKGKLWSQILADVSGLPVNIPVVKEATALGCAIAAGVGAGIFSSMAETGERLVRWERTH------ 488

  Fly   510 TTTDVERKERY----GKWKRAVERSLGWV 534
             |.|.|:.|.|    .||:...:..||.|
E. coli   489 -TPDPEKHELYQDSRDKWQAVYQDQLGLV 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gk2	NP_647655.1	glycerol_kin	31..533	CDD:273549	126/546 (23%)
lsrK	NP_416028.3	PRK10939	10..530	CDD:182853	128/549 (23%)