DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gk2 and YTA7

DIOPT Version :9

Sequence 1:	NP_001286904.1	Gene:	Gk2 / 38221	FlyBaseID:	FBgn0035266	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	NP_011786.1	Gene:	YTA7 / 853186	SGDID:	S000003502	Length:	1379	Species:	Saccharomyces cerevisiae

Alignment Length:	175	Identity:	39/175 - (22%)
Similarity:	61/175 - (34%)	Gaps:	46/175 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 YTTPDFKEIAAHRVELSVITPQDGWYEQDPLEMMASINKCAEEAIKQLPEQGFSASDIVTVGITN 112
            |||    |:........:.|..|....::|.|...|:.       .|:.|:.||..|..|..|.:
Yeast  1225 YTT----ELIQATCTSEITTDDDERARKEPKENEDSLQ-------TQVTEENFSKIDANTNNINH 1278

  Fly   113 QRETTIVWDAVTGKPLYNALLWKDIRTSTTVEQ-----IVAKVQDPNHFRSSTGLPIST------ 166
            .:|...|     .||  |:|       ..|||:     |..:|.:|...:.|....|.|
Yeast  1279 VKEIQSV-----NKP--NSL-------HETVEKRERSPIPKEVVEPEQGKKSDKELILTPEQIKK 1329

  Fly   167 ----------YFSALKIRWLRDNVPEVRQAIRERRCKAGTVDSWI 201
                      .|:..::..:..:|.::....:....|.||||..|
Yeast  1330 VSACLIEHCQNFTVSQLEDVHSSVAKIIWKSKSAWDKTGTVDEII 1374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gk2	NP_001286904.1	glycerol_kin	31..533	CDD:273549	39/175 (22%)
Gk2	NP_001286904.1	FGGY_GK1-3_metazoa	31..533	CDD:212664	39/175 (22%)
YTA7	NP_011786.1	RecA-like_Yta7-like	414..583	CDD:410925
		SpoVK	430..>882	CDD:223540
		Bromo_TBP7_like	979..1098	CDD:99923
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900