DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gk2 and katnal2

DIOPT Version :9

Sequence 1:	NP_001286904.1	Gene:	Gk2 / 38221	FlyBaseID:	FBgn0035266	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	NP_001032491.1	Gene:	katnal2 / 641431	ZFINID:	ZDB-GENE-051113-156	Length:	485	Species:	Danio rerio

Alignment Length:	247	Identity:	53/247 - (21%)
Similarity:	85/247 - (34%)	Gaps:	69/247 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 KQLPEQGFSASDIVTVGITNQRETTIVWDAVTGKPLYNALLWKDIRTSTTVEQIVAKVQDPNHFR 157
            |:|.|||.|.. |.:.|   :|..|:        |..|::.....|  .||::..:|:...:..:
Zfish    91 KKLAEQGESRR-IKSCG---KRSHTL--------PRINSIQRPSSR--NTVKKSESKLTGRDFSK 141

  Fly   158 SSTGLPISTYFSALKIRWLRDNVPEVRQAIRE----RRCKAGTVDSWIVWNLTNGALHITDVTNA 218
            ||.|..::   ||..:.:..:..|.:|....|    |:.....:....|....|..||..|.|..
Zfish   142 SSDGDRLT---SADTLGFGLNVSPIIRNGAEEGTHMRKIDYRNLIQDAVRGAANDTLHNADFTEQ 203

  Fly   219 SRTLL-------MNLETQ-----------------AWDPVL----LKTFGIREEMLPTIHSCSEI 255
            .|.|.       ||.:.:                 .||.::    .|.. ::|.::..| ...::
Zfish   204 ERLLKPVSALIGMNSDMKELAAVISRDIYLHNPNVRWDDIIGLEAAKRL-VKEAVVYPI-KYPQL 266

  Fly   256 FGKITSERSPLRGMTLSGIMGNQQASLLGQMCVKPGQTKNTYRSGCFLLCNT 307
            |   |...||.:|:.|.|               .||..|..........|||
Zfish   267 F---TGILSPWKGLLLYG---------------PPGTGKTMLAKAVATECNT 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gk2	NP_001286904.1	glycerol_kin	31..533	CDD:273549	53/247 (21%)
Gk2	NP_001286904.1	FGGY_GK1-3_metazoa	31..533	CDD:212664	53/247 (21%)
katnal2	NP_001032491.1	LisH	25..55	CDD:128913
		P-loop_NTPase	242..>296	CDD:304359	13/73 (18%)
		AAA	273..410	CDD:214640	10/43 (23%)
		AAA	277..409	CDD:278434	8/39 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900