Protein Alignment Gk2 and FGGY

DIOPT Version :9

• Sequence 1: NP_001286904.1
• Gene: Gk2 / 38221
• FlyBaseID: FBgn0035266
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001106882.1
• Gene: FGGY / 55277
• HGNCID: 25610
• Length: 575
• Species: Homo sapiens
• Alignment Length: 582
• Identity: 129/582 - (22%)
• Similarity: 209/582 - (35%)
• Gaps: 188/582 - (32%)

  Fly    68 PQDGWYEQDPLEMMAS---INKCAEEAI--KQLPEQGFSAS-DIVTVG------ITNQRETTIVW 120
            ||...:||...::.|:   :.|...:.|  .|:...||.|: .:|.:.      ..||.
Human    46 PQFNHHEQSSEDIWAACCVVTKKVVQGIDLNQIRGLGFDATCSLVVLDKQFHPLPVNQE------ 104

  Fly   121 DAVTGKPLYNALLWKDIRTSTTVEQIVAKVQDPNHFRSS----TGLPISTYFSALKIRWLRDNVP 181
                |....|.::|.|.|..:.|.:|       |..:.|    .|..:|....|.|:.||::|:.
Human   105 ----GDSHRNVIMWLDHRAVSQVNRI-------NETKHSVLQYVGGVMSVEMQAPKLLWLKENLR 158

  Fly   182 EVRQAIRERRC--KAG---TVDSWIVWNLTNGALHITDVTNASRTLLMNLET----QAWDPVLLK 237
            |:        |  |||   .:..::.|..|.       ||..|...|:...|    :.||....|
Human   159 EI--------CWDKAGHFFDLPDFLSWKATG-------VTARSLCSLVCKWTYSAEKGWDDSFWK 208

  Fly   238 TFGIREEMLPTIHSCSEIFGKITSERSP-------------------LRGMTLS----------- 272
            ..|:.:.:       ::.:.||.::..|                   |.|:.::
Human   209 MIGLEDFV-------ADNYSKIGNQVLPPGASLGNGLTPEAARDLGLLPGIAVAASLIDAHAGGL 266

  Fly   273 GIMGNQQASLLGQMCVKPGQTKNTYRSGCFLLCNTGD-------KPVFSRHGLLTTVAYKLGP-- 328
            |::|   |.:.|...:..||   ...|...::|.|..       .|:|        |....||
Human   267 GVIG---ADVRGHGLICEGQ---PVTSRLAVICGTSSCHMGISKDPIF--------VPGVWGPYF 317

  Fly   329 --QAPTIYAIEGAVSVA---------GHA--------------------------------LSWL 350
              ..|..:..||..||.         |||                                :.:|
Human   318 SAMVPGFWLNEGGQSVTGKLIDHMVQGHAAFPELQVKATARCQSIYAYLNSHLDLIKKAQPVGFL 382

  Fly   351 QNKVRILPD-----SRDAEKYAEMVPTSGDVYFVPAFTGLYAPYWRQNARGIIIGLTQFTRKNHI 410
            ...:.:.||     |..|:...:.:.|:|.:| :||...|::|....:.:...:.|:|......|
Human   383 TVDLHVWPDFHGNRSPLADLTLKGMRTTGYLY-IPALAALHSPSSLLSPQVTGLKLSQDLDDLAI 446

  Fly   411 V-RAALESICFQTRDILECMHQECGYEINKLHADGKLTTNNLLMQLQADTIGMPVFRSQLMDSTA 474
            : .|.:::|...||.|:|.| :..|:.|:.|...|.|:.|.|.:|:.||..||||..||.::|..
Human   447 LYLATVQAIALGTRFIIEAM-EAAGHSISTLFLCGGLSKNPLFVQMHADITGMPVVLSQEVESVL 510

  Fly   475 FGAAMCAAQADG--------------VNLCQFE--PEKRYYENVHYDTFLATTTDVERKERY 520
            .|||:..|.|.|              |....|.  .:|:||:. .|..||..   ||.::.|
Human   511 VGAAVLGACASGDFASVQEAMAKMSKVGKVVFPRLQDKKYYDK-KYQVFLKL---VEHQKEY 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gk2	NP_001286904.1	glycerol_kin	31..533	CDD:273549	129/582 (22%)
		FGGY_GK1-3_metazoa	31..533	CDD:212664	129/582 (22%)
FGGY	NP_001106882.1	FGGY_YpCarbK_like	10..568	CDD:212663	128/580 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810