DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gk2 and kif23

DIOPT Version :9

Sequence 1:	NP_001286904.1	Gene:	Gk2 / 38221	FlyBaseID:	FBgn0035266	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	XP_012814357.1	Gene:	kif23 / 496517	XenbaseID:	XB-GENE-999865	Length:	970	Species:	Xenopus tropicalis

Alignment Length:	202	Identity:	43/202 - (21%)
Similarity:	70/202 - (34%)	Gaps:	65/202 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 IVTVGITNQRETTIVWDAVTGKP------------LYNALLWKDIRTSTTVEQIVAKVQDPNHFR 157
            :.|.|:|...:|    ..:||.|            ::|::      .:...::.|.|..|.|
Frog   109 LFTYGVTGSGKT----HTMTGSPGDGGLLPRCLSMIFNSI------GNFQAKRYVFKPDDKN--- 160

  Fly   158 SSTGLPISTYFSALKIRWLRDNVPEV-------RQAIR---------ERRCKAGTVDSWIVWNLT 206
               |:.:.....||..|..|:..|::       ||.:.         :.:||...||...|:::.
Frog   161 ---GMDVQNEVDALLERQKREVQPQLITRTPLSRQRMDPEFADMINIQEQCKVEDVDEDSVYSVF 222

  Fly   207 NGALHITDVTNASRTLLMNLETQAWDPVLLK--TFGIREEMLPT--------------IHSCSEI 255
            ...:.|  ..|....|   ||....||:..|  |.|...|.:|.              |..|:|:
Frog   223 VSYIEI--YNNYIYDL---LEEVPLDPIKPKWNTPGRNAEFIPPQSRILREDLNHNMYIAGCTEV 282

  Fly   256 FGKITSE 262
            ..|.|.|
Frog   283 EVKSTEE 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gk2	NP_001286904.1	glycerol_kin	31..533	CDD:273549	43/202 (21%)
Gk2	NP_001286904.1	FGGY_GK1-3_metazoa	31..533	CDD:212664	43/202 (21%)
kif23	XP_012814357.1	KISc_KIF23_like	25..448	CDD:276819	43/202 (21%)
		CwlO1	543..>694	CDD:226400
		PHA03307	<696..>821	CDD:223039
		MKLP1_Arf_bdg	811..911	CDD:374613
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900