DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gk2 and Fggy

DIOPT Version :9

Sequence 1:	NP_001286904.1	Gene:	Gk2 / 38221	FlyBaseID:	FBgn0035266	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	XP_038965462.1	Gene:	Fggy / 298250	RGDID:	1359429	Length:	558	Species:	Rattus norvegicus

Alignment Length:	497	Identity:	114/497 - (22%)
Similarity:	185/497 - (37%)	Gaps:	122/497 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 PQDGWYEQDPLEMMASINKCAEEAIKQLPEQGFSASDIVTVGITNQRETTIVWDAV--------T 124
            ||...:||...::.|:..:..:|.:     ||..|..|..:|. :...:.:|.|..        .
  Rat    77 PQFNHHEQSSEDIWAACCRVTKEIV-----QGIDAHRIRGLGF-DATCSLVVLDKEFHPLPVNRE 135

  Fly   125 GKPLYNALLWKDIRTSTTVEQIVAKVQDPNHFRSS----TGLPISTYFSALKIRWLRDNVPEVRQ 185
            |....|.::|.|.|..:.|.:|       |..:.|    .|..:|....|.|:.||::|:.|:
  Rat   136 GDSSRNIIMWLDHRAVSQVHRI-------NETKHSVLQYVGGVMSVEMQAPKLLWLKENLREI-- 191

  Fly   186 AIRERRC--KAG---TVDSWIVWNLTNGALHITDVTNASRTLLMNLET----QAWDPVLLKTFGI 241
                  |  |||   .:..::.|..|.       ||..|...|:...|    :.||....|..|:
  Rat   192 ------CWDKAGHFFDLPDFLSWKATG-------VTARSLCSLVCKWTYSAEKGWDDSFWKMIGL 243

  Fly   242 REEML-------------PTIHSCSEIFGKITSERSPLRGMTLS-----------GIMGNQQASL 282
             |:::             |.....|.:..:...|.....|:.::           |::|   |.:
  Rat   244 -EDLIGDNYNKIGNLVLPPGASLGSGLIPEAARELGLPSGIAVAASLIDAHAGGLGVIG---ADV 304

  Fly   283 LGQMCVKPGQTKNTYRSGCFLLCNTGD-------KPVFSRHGLLTTVAYKLGP----QAPTIYAI 336
            .|......||   ...|...::|.|..       .|:|        |....||    ..|..:..
  Rat   305 RGHGLTCEGQ---PVTSRLAVICGTSSCHMGISKDPIF--------VPGVWGPYFSAMVPGFWLN 358

  Fly   337 EGAVSVAGHALSWLQNKVRILPDSR------------------DAEKYAEMVP-TSGDVYFVPAF 382
            ||..||.|..:..:.......|:.:                  |..|.|:.|. .:.|::..|.|
  Rat   359 EGGQSVTGKLIDHMVQSHPAFPELQAKATARCQSIYAYLNSHLDLIKKAQPVGFLTVDLHVWPDF 423

  Fly   383 TGLYAPYWRQNARGIIIGLTQFTRKNHIV---RAALESICFQTRDILECMHQECGYEINKLHADG 444
            .|..:|......:|::.|||.....:.:.   .|.:::|.|.||.|:|.| :..|:.::.|...|
  Rat   424 HGNRSPLADLTLKGMVTGLTLSRDLDDLAVLYLATIQAIAFGTRFIIETM-EAAGHSLSTLFLCG 487

  Fly   445 KLTTNNLLMQLQADTIGMPVFRSQLMDSTAFGAAMCAAQADG 486
            .|:.|.|.:|:.||..||||..||.::|...|||:..|.|.|
  Rat   488 GLSKNPLFVQMHADITGMPVVLSQEVESVLVGAAILGACASG 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gk2	NP_001286904.1	glycerol_kin	31..533	CDD:273549	114/497 (23%)
Gk2	NP_001286904.1	FGGY_GK1-3_metazoa	31..533	CDD:212664	114/497 (23%)
Fggy	XP_038965462.1	FGGY_YpCarbK_like	41..536	CDD:212663	114/497 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810