Protein Alignment Gk2 and R11F4.1

DIOPT Version :9

• Sequence 1: NP_001286904.1
• Gene: Gk2 / 38221
• FlyBaseID: FBgn0035266
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_494721.1
• Gene: R11F4.1 / 173747
• WormBaseID: WBGene00020007
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 506
• Identity: 199/506 - (39%)
• Similarity: 319/506 - (63%)
• Gaps: 12/506 - (2%)

  Fly    32 LVGVIDEGTKTIGFSIYTTPDFKEIAAHRVELSVITPQDGWYEQDPLEMMASINKCAEEAIKQLP 96
            |:..||:||.:..|.::.....:.:.:|::|:..:.|..||.|.||:|:..::..|..:.|::|.
 Worm     3 LLAAIDQGTSSSRFLVFEADTGELVTSHQIEVRQLFPHGGWVEMDPMELYDTVVSCISKTIEKLE 67

  Fly    97 EQGFSASDIVTVGITNQRETTIVWDAVTGKPLYNALLWKDIRTSTTVEQIVAKV--QDPNHFRSS 159
            ..|.||.:|.:||:.|||||:||||..||||||||::|.|.|||:..::.:::.  :..:.||:.
 Worm    68 NLGISADEIKSVGVANQRETSIVWDKETGKPLYNAIVWLDTRTSSLADEAISRTASKSKDEFRAK 132

  Fly   160 TGLPISTYFSALKIRWLRDNVPEVRQAIRERRCKAGTVDSWIVWNLTNGALHITDVTNASRTLLM 224
            |||||..||||||::||..|||||::|..:.....||||:|::|.|| || ::|||:|||||||:
 Worm   133 TGLPIHPYFSALKLKWLFQNVPEVKKAYADGNLMFGTVDTWLIWKLT-GA-YVTDVSNASRTLLL 195

  Fly   225 NLETQAWDPVLLKTFGIREEMLPTIHSCSEIFGKITSERSPLRGMTLSGIMGNQQASLLGQMCVK 289
            :|..:.|...|.:.|.:..|:||.|.|.:|::|..  ::.||.|:.|||.:|:|||:::|..|:.
 Worm   196 DLHKRKWSTQLCEFFDLPIEILPEIRSSAEVYGHF--DKGPLEGVPLSGCLGDQQAAMVGHQCLN 258

  Fly   290 PGQTKNTYRSGCFLLCNTGDKPVFSRHGLLTTVAYKLGPQAPTIYAIEGAVSVAGHALSWLQNKV 354
            .|||||||.:|.|:|||.|.:|:.|::||||||.::.|..:|.:||:||:.|:.|:.:.:|::..
 Worm   259 AGQTKNTYGTGTFMLCNIGTRPIISKNGLLTTVGFQFGADSPVVYALEGSGSIGGNVVRFLRDNF 323

  Fly   355 RILPDSRDAEKYAEMVPTSGDVYFVPAFTGLYAPYWRQNARGIIIGLTQFTRKNHIVRAALESIC 419
            :.:.|:::.|.....|..:...||||:|||||.|||...|||.|:||||.|::.||..|||.::.
 Worm   324 KFISDAKEMEGLCRSVEDTSGAYFVPSFTGLYTPYWDSTARGTILGLTQVTQREHICLAALRAVA 388

  Fly   420 FQTRDILECMHQ--ECGYEINKLHADGKLTTNNLLMQLQADTIGMPVFRSQLMDSTAFGAAMCAA 482
            ||:.:::..:.|  |.|.::..|..||.:..|.|..::|||.:|..:...::.:.:.:|||:
 Worm   389 FQSAEMIAAVEQDLEGGTKVTTLKVDGGMIANKLFNEIQADIMGRDIVTPKITEISGWGAAV--- 450

  Fly   483 QADGVNLCQFEPEKRYYENVHYDTFLATTTDVERKERYGKWKRAVERSLGW 533
             |.|:...|...::...::...:.:.....|..|.....:||.||:||.||
 Worm   451 -AGGIGAQQISLDEFLQQSSEDNRYTPQKDDNWRSAELARWKEAVKRSCGW 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gk2	NP_001286904.1	glycerol_kin	31..533	CDD:273549	197/504 (39%)
		FGGY_GK1-3_metazoa	31..533	CDD:212664	197/504 (39%)
R11F4.1	NP_494721.1	glycerol_kin	3..500	CDD:273549	197/504 (39%)
		FGGY_GK	3..491	CDD:198347	191/495 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157593
Domainoid	1	1.000	163	1.000	Domainoid score	I2404
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H21848
Inparanoid	1	1.050	429	1.000	Inparanoid score	I967
Isobase	1	0.950	-	0	Normalized mean entropy	S1003
OMA	1	1.010	-	-		QHG60628
OrthoDB	1	1.010	-	-		D352321at33208
OrthoFinder	1	1.000	-	-		FOG0001035
OrthoInspector	1	1.000	-	-		otm14516
orthoMCL	1	0.900	-	-		OOG6_100613
Panther	1	1.100	-	-	O	PTHR10196
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1107
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.760