Protein Alignment Gk2 and AgaP_AGAP005956

DIOPT Version :9

• Sequence 1: NP_001286904.1
• Gene: Gk2 / 38221
• FlyBaseID: FBgn0035266
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_315996.3
• Gene: AgaP_AGAP005956 / 1276627
• VectorBaseID: AGAP005956
• Length: 556
• Species: Anopheles gambiae
• Alignment Length: 612
• Identity: 120/612 - (19%)
• Similarity: 216/612 - (35%)
• Gaps: 167/612 - (27%)

  Fly    32 LVGVIDEGTKTIGFSIYTTPDFKEIAAHRVE-LSVITPQDGWYEQDPLEMMASINKC-------- 87
            |:|| |.||.:...::.|...  |:....|: :.....|..:|||...::.:::.:|
Mosquito    10 LIGV-DVGTGSARAALVTGKG--EVLQTCVKPIQTWNTQPNYYEQSSDDIWSAVCECVKNVTFGY 71

  Fly    88 AEEAIKQLPEQGFSASDIVTVGITNQRETTIVWDAVTGKPLYNALLWKDIRTSTTVEQIVAKVQD 152
            |:|.||.:   ||.|:..:.|.....:..|:...:...:  .|.:||.|.|    .|:....:..
Mosquito    72 AKEQIKGI---GFDATCSLVVLDGQMQPLTVCPSSKDNQ--RNVILWMDHR----AEEEARFINA 127

  Fly   153 PNH-FRSSTGLPISTYFSALKIRWLRDNVPEVRQAIRERRCKAGTVDSWIVWNLTNGALHITD-- 214
            .:| ..:..|..||......|:.||:.::.:.                  ||........:.|
Mosquito   128 THHQMLNYVGGSISLEMEVPKLLWLKRDMHDA------------------VWTKVGAFYDLPDYL 174

  Fly   215 ---VTNAS-RTLL-------MNLETQAWDPVLLKTFGIREEMLPTIHSCSEIFGKITSERSPLRG 268
               .|.|. |::.       .:.|.:.|....|:|.|:.:::  .:.|...|...:.:..:|
Mosquito   175 TFRATGADCRSICSAVCKWNYDAEDRCWSEDFLQTIGLVDDL--RVDSWRLIGTHVANPGAP--- 234

  Fly   269 MTLSGIMGNQQASLLGQMCVKPGQTKNTYR----------SGC-----------------FLLCN 306
              :.|.:..|.|..||   :.||....:..          .||                 .::|.
Mosquito   235 --IDGGLSRQAAQELG---LNPGTAVASSMIDAHAGALALLGCEGPPGRAGDGSGLTSKMAIICG 294

  Fly   307 TGD-------KPVFS-------RHGLLTTVAYKLGPQAPTIYAIEGAVSVAGHALSW-LQNKV-- 354
            |..       :||.:       :|.::           |.:|..|...|..|..:.: ||...
Mosquito   295 TSSCHMSLTKRPVLAPGIWGPYKHAII-----------PDLYLNEAGQSATGVLIDYMLQTHPCY 348

  Fly   355 -RILPD--SRDAEKYA-------EMVPTSG---------DVYFVPAFTGLYAPYWRQNARGIIIG 400
             ::|.:  ..:.:.||       |:....|         |::..|.|.|..:|....|.:|:|.|
Mosquito   349 DQLLKEHGGSNGKIYAFLNTFLDELAKKQGESSVHRLTIDLHVWPDFHGNRSPLADPNLKGMISG 413

  Fly   401 LTQFTRKNH---IVRAALESICFQTRDILECMHQECGYEINKLHADGKLTTNNLLMQLQADTIGM 462
            ||......:   |..|.::::.:.||.||:.:.......|..:...|.|:.|:|.:|..||...:
Mosquito   414 LTMTKDVQNLALIYLALMQALAYGTRHILQVLEASGREPITSILLCGGLSKNSLFVQTHADICSV 478

  Fly   463 PVFRSQLMDSTAFGAAMCAAQADGVNLCQFEPEKRYYENVHYDTFLATTTDVERKERYGKWKRAV 527
            ||......::...|:||..|.|.|:                ||:.....:.:      |...:.|
Mosquito   479 PVLLPSEPEAVLLGSAMMGAYAAGL----------------YDSLELAASGM------GGSAKVV 521

  Fly   528 ERSLGWVIKQKKTREYTEENYRMLSSL 554
            :..|     ...||:|.|..||:...:
Mosquito   522 KPDL-----SDSTRDYHERKYRVFQRM 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gk2	NP_001286904.1	glycerol_kin	31..533	CDD:273549	114/589 (19%)
		FGGY_GK1-3_metazoa	31..533	CDD:212664	114/589 (19%)
AgaP_AGAP005956	XP_315996.3	5C_CHO_kinase	9..550	CDD:273552	120/612 (20%)
		FGGY_YpCarbK_like	9..550	CDD:212663	120/612 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810