Protein Alignment Gk2 and gk

DIOPT Version :10

• Sequence 1: NP_647655.1
• Gene: Gk2 / 38221
• FlyBaseID: FBgn0035266
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_012811696.1
• Gene: gk / 100038285
• XenbaseID: XB-GENE-961541
• Length: 562
• Species: Xenopus tropicalis
• Alignment Length: 555
• Identity: 264/555 - (47%)
• Similarity: 374/555 - (67%)
• Gaps: 18/555 - (3%)

  Fly    32 LVGVIDEGTKTIGFSIYTTPDFKEIAAHRVELSVITPQDGWYEQDPLEMMASINKCAEEAIKQLP 96
            |||.||:||.:..|.::.....:.::.|:||:....|::||.||||.|::.|:.:|.|:..::|.
 Frog    12 LVGAIDQGTSSTRFLVFNAKTAELLSHHQVEIKQKFPKEGWVEQDPKEILQSVYECVEKTCEKLT 76

  Fly    97 EQGFSASDIVTVGITNQRETTIVWDAVTGKPLYNALLWKDIRTSTTVEQIVAKV--QDPNHFRSS 159
            :.....::|..:|::||||||:|||..||:|||||::|.|:||.:|||:::.::  ::.|.|:|.
 Frog    77 QLNIDITNIKAIGVSNQRETTVVWDKTTGEPLYNAVVWLDLRTQSTVERLLKRIPGKNKNFFKSR 141

  Fly   160 TGLPISTYFSALKIRWLRDNVPEVRQAIRERRCKAGTVDSWIVWNLT---NGALHITDVTNASRT 221
            ||||:||||||:|||||.|||.|:|.|:.|.|...|||||||:|:||   ||.:|.|||||||||
 Frog   142 TGLPLSTYFSAVKIRWLLDNVEEIRHAVSEGRAMFGTVDSWIIWSLTGAKNGGVHCTDVTNASRT 206

  Fly   222 LLMNLETQAWDPVLLKTFGIREEMLPTIHSCSEIFG--KI--TSERSPLRGMTLSGIMGNQQASL 282
            :|.|:.|..||..|.:.|.|..|:||.:.|.|||:|  ||  :.:...|.|:.:||.:|:|.|:|
 Frog   207 MLFNIHTLEWDTELCQFFDIPMELLPKVRSSSEIYGLMKICPSLKSGALTGVPISGCLGDQSAAL 271

  Fly   283 LGQMCVKPGQTKNTYRSGCFLLCNTGDKPVFSRHGLLTTVAYKLGPQAPTIYAIEGAVSVAGHAL 347
            :||||.:.||.||||.:|||||||||.|||.|.||||||||||||...|..||:||:|::||..:
 Frog   272 VGQMCFQDGQAKNTYGTGCFLLCNTGSKPVLSEHGLLTTVAYKLGRDKPACYALEGSVAIAGAVV 336

  Fly   348 SWLQNKVRILPDSRDAEKYAEMVPTSGDVYFVPAFTGLYAPYWRQNARGIIIGLTQFTRKNHIVR 412
            .||::.:.|:..:.:.||.|..|.||...||||||:|||||||..:|||||.||||||.:|||..
 Frog   337 RWLRDNLGIVKTTEEVEKLAAEVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNRNHIAF 401

  Fly   413 AALESICFQTRDILECMHQECGYEINKLHADGKLTTNNLLMQLQADTIGMPVFRSQLMDSTAFGA 477
            ||||::|||||:||:.|:::||..:|:|..||.:|:|.:|||||||.:.:||.:..:.::||.||
 Frog   402 AALEAVCFQTREILDAMNKDCGIPLNQLQVDGGMTSNKILMQLQADILCIPVVKPSMPETTALGA 466

  Fly   478 AMCAAQADGVNLCQFEPEKRYYENVHYDTFLATTTDVERKERYGKWKRAVERSLGWVIKQKKTRE 542
            ||.|..|:||.:....|..  ...|..:.|.......|.:.||.:||:||.:|:||     ::.|
 Frog   467 AMAAGAAEGVGVWSLNPGD--LTAVTCERFEPQINPEESEFRYARWKKAVMKSMGW-----ESAE 524

  Fly   543 YTEEN--YRMLSSLPASIFLISSFAMLVHSLAASG 575
            .|..|  ..:..|||...:::||..:|:.:...||
 Frog   525 PTNGNGDCSIFCSLPLGFYIVSSMVLLIGAKYISG 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gk2	NP_647655.1	glycerol_kin	31..533	CDD:273549	251/509 (49%)
gk	XP_012811696.1	ASKHA_NBD_FGGY_GK1-3-like	11..517	CDD:466802	250/506 (49%)