Protein Alignment PIG-Wb and PIGW

DIOPT Version :10

• Sequence 1: NP_647654.1
• Gene: PIG-Wb / 38220
• FlyBaseID: FBgn0035265
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_848612.2
• Gene: PIGW / 284098
• HGNCID: 23213
• Length: 504
• Species: Homo sapiens
• Alignment Length: 511
• Identity: 138/511 - (27%)
• Similarity: 226/511 - (44%)
• Gaps: 96/511 - (18%)

  Fly    51 SGESLLLILSTL----WCILLARVVCQKLRLHGSADLC---------YATEFLLVILPCILLVSV 102
            :|.::|.|...|    :|||     |:...:..|..||         :.|:|:::|:|.:..:::
Human    15 NGTTVLEITQGLCFPAFCIL-----CRGFLIIFSQYLCSFSPTWKTRFLTDFVVLIVPMVATLTI 74

  Fly   103 AVDYSGYIGLLMLVATLWFLRTSRALERART---RVQF----------DLGGNRPMCLSILRALT 154
               ::.:|.|.:|...::.......:.|.||   |:.|          .|.......:|..|.:|
Human    75 ---WASFILLELLGVIIFGAGLLYQIYRRRTCYARLPFLKILEKFLNISLESEYNPAISCFRVIT 136

  Fly   155 HLITAVCILAIDFGSFYRPYRKSRQFGAKLMDTGIGLFVFTMAMVS---RRTRHWSDLR----RS 212
            ...||:.|||:||..|.|.:.|:..:|...||.|:|.|||..|||.   ||.::....:    .:
Human   137 SAFTAIAILAVDFPLFPRRFAKTELYGTGAMDFGVGGFVFGSAMVCLEVRRRKYMEGSKLHYFTN 201

  Fly   213 VIYSALPLILLGLARTVSILTLSYGQDAHEYGQHLNAFFTLGFTKFLGSLVSILARKDLHLLPL- 276
            .:||..||:.||:.|...|.::.|.:...|||.|.|.|||:...|.:..|:.|       :.||
Human   202 SLYSVWPLVFLGIGRLAIIKSIGYQEHLTEYGVHWNFFFTIIVVKLITPLLLI-------IFPLN 259

  Fly   277 -----GFGLLVIHQFGLSVLGISDYVM---NEDVERSSFLNANREGLVSLPGFVGLFLLSIYVNR 333
                 ..|:.|::|..|....:...::   :....|...|||||||::|..|:|.:.:..:....
Human   260 KSWIIALGITVLYQLALDFTSLKRLILYGTDGSGTRVGLLNANREGIISTLGYVAIHMAGVQTGL 324

  Fly   334 WMVAKSLLTYSEFVRKLRRLFYLVLILWTSFVISAYEI-----GISRVTCNLGYVIWMLAIGSTT 393
            :|...     ...::.|.::...:|:...|..||.|.:     .:||...||.:.||::| .|..
Human   325 YMHKN-----RSHIKDLIKVACFLLLAAISLFISLYVVQVNVEAVSRRMANLAFCIWIVA-SSLI 383

  Fly   394 LCAS--FGAI-----DFAINSVMPWDPNPWEDHEKGLLSGEAVVKKRGGSVVP--------FTIS 443
            |.:|  .|.|     .|.|...:.  |..|:     |:......||...|:||        ..:.
Human   384 LLSSLLLGDIILSFAKFLIKGALV--PCSWK-----LIQSPVTNKKHSESLVPEAERMEPSLCLI 441

  Fly   444 QALNKNGLTFFLVANILTGMVNIFLRPEDRSHSESVIILLV---YMFLATKLVHEL 496
            .|||:..|.|||::||.||::|:.:   |..||.::..|.|   |||....:|:.|
Human   442 TALNRKQLIFFLLSNITTGLINLMV---DTLHSSTLWALFVVNLYMFSNCLIVYVL 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-Wb	NP_647654.1	GWT1	85..503	CDD:470470	127/464 (27%)
PIGW	NP_848612.2	GWT1	4..497	CDD:470470	138/511 (27%)