DRSC/TRiP Functional Genomics Resources

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Protein Alignment Oseg4 and Tulp4

DIOPT Version :9

Sequence 1:NP_001261278.1 Gene:Oseg4 / 38219 FlyBaseID:FBgn0035264 Length:1205 Species:Drosophila melanogaster
Sequence 2:NP_001102607.1 Gene:Tulp4 / 499016 RGDID:1564487 Length:1546 Species:Rattus norvegicus


Alignment Length:526 Identity:124/526 - (23%)
Similarity:219/526 - (41%) Gaps:124/526 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 LSKKIAIPNNVKLNCIAWNK--EEGYIAVAGTDGLLKV------LKLDQATPNGQSKGGLAAVSN 61
            ||.|..:|.:.|...:...:  |||::|.....|::.|      .:.|::||.            
  Rat    20 LSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFTSSHCRRDRSTPQ------------ 72

  Fly    62 LSMNQTLDGHKESVRVVTWNDAQQKLTSSDTDGVIMVWMLYKGSWYEEMTNDRKKSTVASMSWTS 126
             .:|..|.||...|.:|.||:..|||.:.|.||.|.||:.|:|.|..|:.||| .:.|:..:|:.
  Rat    73 -RINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDR-GAQVSDFTWSH 135

  Fly   127 DGSRICIVYEDGAIIVGSVDGNRIFGKELK-GTHLTGVQWSPDNRLILFALANG-----ECH--- 182
            ||::..|.|.||.::||||.|.|.:..|:. .:.:|...|:||::.:||..|:|     :||   
  Rat   136 DGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQQVLFGTADGQVIVMDCHGRM 200

  Fly   183 -----LYDNQGNFAMKLHIQCVNISGGSSS-----------RGHRIASICWFSGRVVQSRKRPVL 231
                 |:::.|..:|..:.....:...|.|           .|.....|      .||:.| |:|
  Rat   201 LAHVLLHESDGILSMSWNYPIFLVEDSSESDTDSDDYSPPQDGPAAYPI------PVQNIK-PLL 258

  Fly   232 AICYENGRVQIMRNENDDAPAIFDTGMRNVDAKWNHDGTVLAICGTTLDAVSPTSQRDTN----- 291
            .:.:.:|.:.:|.|.:|.:|.:..:|::.|.|:|...|.:||:.|  ::..:..|:....     
  Rat   259 TVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLAVAG--MEQQAQLSELPNGPLLKS 321

  Fly   292 -QVCFYSPLGKIYRTL-KVPGTDITSLSWEGKSLRIAMAVDSFIYFANI--RPDYIWCYFEKTVV 352
             .|.||:..|:...|| .:....|.|:.|..:..|:.||....:|...:  |...:....::.: 
  Rat   322 AMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMASGPALYVVRVEHRVSSLQLLCQQAI- 385

  Fly   353 FLNSGSATRES--------PMSVITFWNTVSNQSFLKEVEPTL-------------CLASSSEHC 396
                .|..||.        |..:.::.:|    :|:..::|.:             ...:...||
  Rat   386 ----ASTLREDKDVNKLTLPPRLCSYLST----AFIPTIKPPIPDPNNMRDFVSYPSAGNERLHC 442

  Fly   397 VL---------GVECVSSNIKEIA----------LSTL-------ENRSNPADDRVYQLLLCNSI 435
            .:         |..|.:..::.:.          :|.|       :.|::...|.:|.   .|.|
  Rat   443 TMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKLRPEFVIMDPRTDSKSDEIYG---NNLI 504

  Fly   436 GTTVDS 441
            .|.:||
  Rat   505 STVIDS 510

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Oseg4NP_001261278.1 WD40 <7..217 CDD:225201 68/242 (28%)
WD40 <18..242 CDD:295369 71/256 (28%)
WD40 repeat 19..70 CDD:293791 11/58 (19%)
WD40 repeat 76..115 CDD:293791 18/38 (47%)
WD40 repeat 119..152 CDD:293791 14/32 (44%)
WD40 repeat 161..202 CDD:293791 13/53 (25%)
WD40 repeat 212..280 CDD:293791 19/67 (28%)
WD40 repeat 290..333 CDD:293791 12/49 (24%)
WD40 341..687 CDD:225201 21/148 (14%)
TPR repeat 815..838 CDD:276809
TPR repeat 839..864 CDD:276809
TPR repeat 869..894 CDD:276809
YscO 877..980 CDD:284686
DUF3505 1163..>1188 CDD:288836
Tulp4NP_001102607.1 WD40 <67..217 CDD:225201 55/163 (34%)
WD40 78..>218 CDD:295369 51/140 (36%)
WD40 repeat 85..123 CDD:293791 17/37 (46%)
WD40 repeat 129..166 CDD:293791 14/36 (39%)
WD40 repeat 171..205 CDD:293791 10/33 (30%)
SOCS 373..408 CDD:295349 5/39 (13%)
Tub <588..>646 CDD:279506
Tub <1469..1539 CDD:279506
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2041
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D91334at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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