Protein Alignment Oseg4 and ifta-1

DIOPT Version :10

• Sequence 1: NP_647653.1
• Gene: Oseg4 / 38219
• FlyBaseID: FBgn0035264
• Length: 1205
• Species: Drosophila melanogaster
• Sequence 2: NP_508940.4
• Gene: ifta-1 / 183817
• WormBaseID: WBGene00016935
• Length: 1246
• Species: Caenorhabditis elegans
• Alignment Length: 1283
• Identity: 382/1283 - (29%)
• Similarity: 621/1283 - (48%)
• Gaps: 149/1283 - (11%)

  Fly     1 MFVYLSKKIAIPNNVKLNCIAWNKEEGYIAVAGTDGLLKVLKL-DQATPNGQSKGGLAAVSNLSM 64
            |.|:....:.:|.:.:|:...||....|||..|..|.|||:|: ..||...:|..    .:.|.:
 Worm    21 MSVFRKFNLGLPEHGQLHFAEWNYNSNYIACGGALGKLKVVKIGTDATDLNKSPN----AATLVV 81

  Fly    65 NQTLDGHKESVRVVTWNDAQQKLTSSDTDGVIMVWMLYKGSWYEEMTNDRKKSTVASMSWTSDGS 129
            ||.|:||..:|...|||:..||||:|||.|:|:||.::...|.|||.|:|.||.|.|:.|..:|:
 Worm    82 NQALEGHNATVMNATWNENNQKLTTSDTSGLIIVWGMFNEQWCEEMINNRNKSVVVSICWNLEGT 146

  Fly   130 RICIVYEDGAIIVGSVDGNRIFGKELKGTHLTGVQWSPDNRLILFALANGECHLYDNQGNFAMKL 194
            :|.|.|.||.:|||:::||||:.|||: ..|...:|:||..:::|..|:|:..::|:.|:..:.:
 Worm   147 KIAIAYADGNVIVGTLEGNRIWNKELE-IQLAACEWAPDGDMLIFGTADGKVSVFDDSGSHFLDI 210

  Fly   195 HIQCV---NISGGSSSRGHRIASI-C---W----------------FSGRVVQSRK--------- 227
            .:.|:   ::....:.:.|:...| |   |                |..::.:.|:
 Worm   211 PMHCLEAEDLEQALAKKEHQKEEIVCLKYWSPTLKSKTILDEMERDFERKLEKDREVTGTAIFTN 275

  Fly   228 --------------------------RPVLAICYENGRVQIMRNENDDAPAIFD-TGMRNVDAKW 265
                                      ||...:.|..|.:|:||:.||..|.:.. ...:...|||
 Worm   276 FPTKPPPKELPEHEKNTEPYQPVPPDRPRFVVAYARGMMQLMRSLNDPEPVVVSIPNFKITGAKW 340

  Fly   266 NHDGTVLAICGTTLDAVSPTSQRDTNQVCFYSPLGKIYRTLKVPGTDITSLSWEGKSLRIAMAVD 330
            :.:|..||:||...|...||    .:::.|.|..|.|....:...:.||.:.||...||:|:|..
 Worm   341 SPNGAFLAVCGNDSDKDEPT----FSKIHFLSAYGHIVGYFQTNDSCITGICWESTGLRMAIAAA 401

  Fly   331 SFIYFANIRPDYIWCYFEKTVVFLNSGSATRESPMSVITFWNTVSNQSFLKEVEPTLCLASSSEH 395
            ..:....|||::.|...|:|:|::..   ..|.....|.|::..:::..:|.|.....:|...||
 Worm   402 GTLLIGQIRPEFKWGSIEETIVYVYQ---KEELYQYGIMFYDYKTDEKTVKTVTHFENMAFYREH 463

  Fly   396 CVLGVECVSSNIKEIALSTLENRSNPADDRV---YQLLLCNSIGTTVDSKYTDIRPCFVGINSSY 457
            |||                    .|..||.|   |...|||||||::|...|.:||.|..:|...
 Worm   464 CVL--------------------INRQDDGVIPHYFCQLCNSIGTSLDYNVTTVRPKFACVNGIC 508

  Fly   458 VAIASQEEILIWHYHTPKSASTLHNVKARKEKRFHIDDTPTGVEMAKDLMLSSSSGD-------- 514
            ..|||::...|||:..||    .::|:|             |:.      :...|||
 Worm   509 AVIASEDRYFIWHFVLPK----FNSVQA-------------GIH------VPGKSGDYVLEEQQR 550

  Fly   515 --GHSTQR--GISDPICALALSEKLLLVARESGAINEYSIANVALRNRHLMNAKVYKMAINCNST 575
              .:.|:|  |..|.||||.:.:...::|..||.|...|:.:..:.|.:.::..:..:.:||..|
 Worm   551 TIEYGTKRLLGSKDEICALCIGDTFFMMALLSGGIYRVSLNDGVITNSYPVSPSINSIKLNCTFT 615

  Fly   576 RAAII---DHMGVMTLLDLDDNRETQLNFSRVERKDVWAVSWATDNPLLLALMEKTRMYIFRGND 637
            |.|:|   :.:....||...|..|.:|.::. :::|||...|..:|..:|||.:|.::.|..||.
 Worm   616 RLAVIKLVEQVPFQFLLYEFDGDELKLIYTS-DKRDVWDYEWDQNNSNMLALKDKQKILICDGNS 679

  Fly   638 PEEPVSCSGYICTFEDLEITSVLLDDIISVGELQNFSHIIQLRVKSLRDTDDLLEHVGLEDAKQF 702
            ..|..|.:|.|..|::|.:|:|.::.|:...|....:.|:::.:|:.:|..:|:..:.||:|..:
 Worm   680 ILEQSSVNGSILLFQNLVVTAVNIEKILLTPENPTKTCIVEVMIKAKQDVMNLVNAMKLEEAIDY 744

  Fly   703 IEDNPHPRLWRLLAESALKKLELETAENAFVRCAHYPGIKLVKRLRTIHSKELQRAEISAFYGEF 767
            .|.:||..||.::|..|:.|...:.||:|||:...|.|::|||:||.|.|.:|:.|||.|:....
 Worm   745 AERSPHSELWSMIANYAVFKHAFDCAEHAFVKLGDYAGVQLVKKLRNIQSNDLRNAEIYAYRDTL 809

  Fly   768 EEAEKLYLDADRRDLAIELRMTLCDWFRVVQLYRMGGSGVSDQQMEIAWREIGHHFANLRSWESA 832
            |||:..:|.|||||||:|:...:.|:..|..|.|   :...|:....|:|.:......:..||.|
 Worm   810 EEAKTAFLQADRRDLAVEMYKKVGDYASVYDLIR---NDDDDEGKCDAFRNMAETHYEMMEWEEA 871

  Fly   833 REYYEKSHYLEGYMEALYHLEQFDDLEKCVERLPEKSPLLPKLAEMLASVGMCSEAVQAHLRFGD 897
            .:.|.........::.|.....|.:||.....|.:.|..:..:.:...|.|||.:||:.:||...
 Worm   872 AKAYSYCGDTANQIDCLIRGNLFGELEVLARTLSDDSEFMEVMGDAFTSRGMCDQAVECYLRRSL 936

  Fly   898 QKAAVATCVNLRQWGEAVELAQRFQLPQVQTLIAKHAAQLLQEGRLK--EAIEMQRNAGRHLDAA 960
            .:.|:..|..|.||.:|..:|....:..|:.|:.|.|.::..|...|  .|:.:...||||||||
 Worm   937 PQKALHACKELNQWQKAQFIADANHMENVEGLLGKFAVEMRGESDEKSLSALALYMRAGRHLDAA 1001

  Fly   961 RLLSQMAEREQEKRAPLLRIKKLYVLAALLAEEHLKAVATTEIDYASGRNTLLDS------IALE 1019
            ::...:|:..:.|..|...:|:.|||.|:|.|.|.:.:  .|:......|.|.|:      ::.|
 Worm  1002 KIAFDIAKDRKSKYVPYEELKQCYVLGAVLVENHRQTI--KELRKIDKHNFLEDALDDESGLSAE 1064

  Fly  1020 DAAAIERLWHCAEAYHFMLLAQRQLRFGIVHSAVVTAVRLRDYEDVLPPEHIYSLLALASCADRA 1084
            .:..:|..|..|||:|||::||:......:..|:.|::.|.|||:.|.|..::|::|||:.....
 Worm  1065 QSRILENTWRGAEAFHFMIMAQQHFFENRIKDALQTSLILSDYEEFLDPAEVHSMIALAAANVNQ 1129

  Fly  1085 FGTCSKAFMKLEQQAHLPEATLQRYEELAAGIFAKYDPEDTTGDRVDCYSCGVPVPDSSPSCPEC 1149
            ||.||||.|:||......:|..:....|:..:|::..|.:....:|.|..|...:......|.||
 Worm  1130 FGICSKAMMRLEAFEEFDDAEKEEMRNLSFRLFSENPPVNPNSAKVACSVCDAKIDPYDLQCSEC 1194

  Fly  1150 NARFPACISSGKPITQPTNNIWICTTCHHCAAPTEISRHRTCPLCHSL 1197
            ..:||.||:||:.|..  |..|:|..|.|.|...||.::..|||||.:
 Worm  1195 QTKFPVCIASGRLILD--NIFWLCPRCKHRAHQHEIPKYNCCPLCHDM 1240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oseg4	NP_647653.1	WD40	<18..318	CDD:441893	105/359 (29%)
		WD40 repeat	19..70	CDD:293791	18/51 (35%)
		WD40 repeat	76..115	CDD:293791	19/38 (50%)
		WD40 repeat	119..152	CDD:293791	16/32 (50%)
		WD40 repeat	161..202	CDD:293791	9/43 (21%)
		WD40 repeat	212..280	CDD:293791	23/123 (19%)
		WD40 repeat	290..333	CDD:293791	12/42 (29%)
		COG3899	<710..1118	CDD:443106	132/415 (32%)
ifta-1	NP_508940.4	WD40 repeat	38..87	CDD:293791	18/52 (35%)
		WD40	<83..243	CDD:475233	60/160 (38%)
		WD40 repeat	92..129	CDD:293791	19/36 (53%)
		WD40 repeat	137..173	CDD:293791	17/35 (49%)
		WD40 repeat	176..219	CDD:293791	10/42 (24%)
		ANAPC4_WD40	<334..392	CDD:403945	19/61 (31%)
		LapB	800..994	CDD:442196	55/196 (28%)