DRSC/TRiP Functional Genomics Resources

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Protein Alignment drpr and Fgfr1

DIOPT Version :9

Sequence 1:NP_001261276.1 Gene:drpr / 38218 FlyBaseID:FBgn0027594 Length:1042 Species:Drosophila melanogaster
Sequence 2:NP_077060.1 Gene:Fgfr1 / 79114 RGDID:620713 Length:822 Species:Rattus norvegicus


Alignment Length:303 Identity:58/303 - (19%)
Similarity:96/303 - (31%) Gaps:98/303 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   742 PEGFYGEHCMNTCACPSANFQCHAAHGCVCRSGYTGDNCDELIASQRIADQSENSSRASVALTLV 806
            |.|.  |:|.|    ||.|.:...:...:....|......|.:||::...:       .:|...|
  Rat   578 PPGL--EYCYN----PSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHR-------DLAARNV 629

  Fly   807 LMTLFACIIFAVFIYYRRRVSNLKTEIAHV-HYTHDTN---PPSWPPNHNFDNPVYGMQAETRLL 867
            |:|....:..|.|        .|..:|.|: :|...||   |..|                  :.
  Rat   630 LVTEDNVMKIADF--------GLARDIHHIDYYKKTTNGRLPVKW------------------MA 668

  Fly   868 PNNMRSKMNNFDQRSTMSTDYGDDCNASGRVGSYSINYNHDLLTKNLN-ADRTNPIVYNES---- 927
            |..:      ||:..|..:|          |.|:.:     ||.:... ....||.|..|.    
  Rat   669 PEAL------FDRIYTHQSD----------VWSFGV-----LLWEIFTLGGSPNPGVPVEELFKL 712

  Fly   928 LKEEHVYDEIKH-------------------KEGYKDPVKIYSKILFPEDEYDHLDYSRPSTSQK 973
            |||.|..|:..:                   :..:|..|:...:|:......::||.|.|.....
  Rat   713 LKEGHRMDKPSNCTNELYMMMRDCWNAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQDS 777

  Fly   974 PHYHRMNDAMLNINQDEEKPSNVKNMTVLLNKPLPPTEPEPQH 1016
            |.:.....:..:..:|          :|..::|.|.....|:|
  Rat   778 PSFPDTRSSTCSSGED----------SVFSHEPFPEEPCLPRH 810

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drprNP_001261276.1 EMI 27..92 CDD:284877
EGF_CA 274..319 CDD:304395
DSL <479..518 CDD:302925
DSL <567..606 CDD:302925
Fgfr1NP_077060.1 Ig1_FGFR 40..118 CDD:143174
IG_like 41..118 CDD:214653
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 120..162
I-set 160..247 CDD:254352
Heparin-binding 160..177
Ig2_FGFR 163..247 CDD:143265
IG_like 262..358 CDD:214653
Ig3_FGFR 270..359 CDD:143175
PTKc_FGFR1 464..765 CDD:270678 47/246 (19%)
Pkinase_Tyr 478..754 CDD:285015 46/235 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 770..822 9/51 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0200
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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