DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drpr and Tmeff1

DIOPT Version :9

Sequence 1:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster
Sequence 2:	NP_075409.1	Gene:	Tmeff1 / 63845	RGDID:	62005	Length:	373	Species:	Rattus norvegicus

Alignment Length:	326	Identity:	78/326 - (23%)
Similarity:	107/326 - (32%)	Gaps:	83/326 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   406 CNCKNGAKCSPVNGTCLCAPGWRGPTCEESCEPGTFGQDCALRCD---CQNGAKCEPETGQCLCT 467
            |...:||...|..|...| ||.||.:.  :|......:.....||   |:.|..|:.:.....|.
  Rat    30 CLPGSGASNQPAGGGGDC-PGGRGKSI--NCSELNLRESDIRACDESSCKYGGVCKEDGDGLKCA 91

  Fly   468 AGWKNIKCDRPCDLNHFGQDCAKVCDCHNN------AACNPQNGSCTCAAG--------WTGERC 518
                   |...|..|:. ..|....|.:.|      |||..|......|.|        .:||..
  Rat    92 -------CQFQCHTNYI-PVCGSNGDTYQNECFLRRAACKHQKDITVVARGPCYSDNGSGSGEGE 148

  Fly   519 ERKCDTG------KFGHDCAQKCQCDFNNSLACDATNGRCVCKQDWGGVHCETNCRSGYYGENCD 577
            |.....|      |.| .|..|.:||.      ||.|..|||..|..|......|.|.  |.:.:
  Rat   149 EEGSGAGAHRKHSKCG-PCKYKAECDE------DAENVGCVCNIDCSGYSFNPVCASD--GSSYN 204

  Fly   578 KVC-----RCLNNSSCD-PDSGNCICSAGWTGADCAEPCPPGFYGMECKERCPEILHGNKSCDHI 636
            ..|     .|:.....| ...|:|      |..|..........|::.:   |::.......:.:
  Rat   205 NPCFVREASCIRQEQIDIRHLGHC------TDTDDTSLLGKKDDGLQYR---PDVKDAGDQREDV 260

  Fly   637 TGEILCRTGYIGLTCEH-PCPAGLYGPGCKLKCNCEHGGECNHV----TGQCQCLPGWTGSNCNE 696
                     |||   .| |||..|.|       .|.| |:|..:    ...|:|..|:||.:|.:
  Rat   261 ---------YIG---SHMPCPENLNG-------YCIH-GKCEFIYSTQKASCRCESGYTGQHCEK 305

  Fly   697 S 697
            :
  Rat   306 T 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	27..92	CDD:284877
		EGF_CA	274..319	CDD:304395
		DSL	<479..518	CDD:302925	13/52 (25%)
		DSL	<567..606	CDD:302925	9/44 (20%)
Tmeff1	NP_075409.1	KAZAL	92..136	CDD:197624	12/44 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	140..162		4/21 (19%)
		KAZAL	182..228	CDD:197624	11/47 (23%)
		PHA02887	<268..304	CDD:165214	13/43 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	352..373
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000