DRSC/TRiP Functional Genomics Resources

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Protein Alignment drpr and kdr

DIOPT Version :9

Sequence 1:NP_001261276.1 Gene:drpr / 38218 FlyBaseID:FBgn0027594 Length:1042 Species:Drosophila melanogaster
Sequence 2:NP_001019824.2 Gene:kdr / 554230 ZFINID:ZDB-GENE-041001-112 Length:1357 Species:Danio rerio


Alignment Length:325 Identity:65/325 - (20%)
Similarity:110/325 - (33%) Gaps:85/325 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   659 LYGPGCKLKCNCEHGGECNHVTGQCQCLPGWTGSNCNESCPTDTYGQGCAQRCRCVHHKVCRKAD 723
            :||....|  .|...|..:.||.:.|.:|       .|.||.                :...|:|
Zfish   448 MYGSSPTL--TCTGSGGSSPVTIKWQWMP-------REDCPV----------------RFLPKSD 487

  Fly   724 -GMCICETGW----SGTRCDEVCPEGFYGEHCMNTCACPSANFQ---CHAAHGCVCRSGYTGDNC 780
             .|..|:. |    :.|..:.:..:....|..:.|.:  :...|   .||.:.|:..:....|..
Zfish   488 PSMAKCDK-WREMSNNTGKNPLISQTSVDERTLKTIS--TLKIQKAVDHALYRCIATNKMGQDQR 549

  Fly   781 DELIASQRIADQSENSSRASVALTLVLMTLFACIIFAVFIYYRR--RVSNLKTE----------- 832
            ..:....|..:.|...|.:.:....|:|   .|:...:..|..|  ||:|:...           
Zfish   550 VIVFQVTRFLNLSVLPSSSPIEGQDVIM---RCVADRLLYYNLRWYRVANVANHDPPPAAVPCDT 611

  Fly   833 --IAHVHYTHDTNPPSWPPNHNFDNPV----------YGMQAE-------TRLLPNNMRSK---- 874
              ::|:|..:.|.......|...|.|:          |..|.|       |.|| :|:|.:    
Zfish   612 LTLSHLHQPNVTVSGLQGTNVTLDMPIPNATMMDQGLYACQVEIVGTNEKTCLL-HNLRLRALEM 675

  Fly   875 ----MNNFDQRSTMSTDYGDDCNASGRVGSYSINYNHDLLT----KNLNADRTNPIVYNESLKEE 931
                .|..|||..:|......|..|| ..:.:|.:..|..|    ..:...|:|.::..:.:|:|
Zfish   676 SRIVTNLTDQRVNVSDSTTLVCEVSG-TPTPTIVWTKDNQTVMEGSGVILKRSNRVLTIQRVKKE 739

  Fly   932  931
            Zfish   740  739

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drprNP_001261276.1 EMI 27..92 CDD:284877
EGF_CA 274..319 CDD:304395
DSL <479..518 CDD:302925
DSL <567..606 CDD:302925
kdrNP_001019824.2 Ig_2 143..221 CDD:290606
IG_like 233..331 CDD:214653
Ig 241..335 CDD:299845
IG_like 345..429 CDD:214653
Ig2_VEGFR-2 356..429 CDD:143272
IG 571..654 CDD:214652 16/85 (19%)
Ig 571..654 CDD:299845 16/85 (19%)
I-set 677..763 CDD:254352 15/64 (23%)
IGc2 691..753 CDD:197706 10/50 (20%)
PKc_like 835..1178 CDD:304357
Pkinase_Tyr 843..1171 CDD:285015
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 944..975
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1296..1357
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0200
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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