DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drpr and FGFRL1

DIOPT Version :9

Sequence 1:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster
Sequence 2:	XP_024309860.1	Gene:	FGFRL1 / 53834	HGNCID:	3693	Length:	527	Species:	Homo sapiens

Alignment Length:	211	Identity:	47/211 - (22%)
Similarity:	76/211 - (36%)	Gaps:	38/211 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   723 DGMCICETGWSGTRCDEVCPEGFYGEHCMNTCACPSANFQCHAAHGCVCRS-GYTGDNCDELI-A 785
            ||..| .:|||..|   |.|:|...:......|   ..:.|.|.:|....| .||....|::. .
Human    89 DGRTI-HSGWSRFR---VLPQGLKVKQVEREDA---GVYVCKATNGFGSLSVNYTLVVLDDISPG 146

  Fly   786 SQRIADQSENSSRASVALTLVLMTLFACIIFAVFIYYRRRV------SNLKTE-IAHVHYTHDTN 843
            .:.:...|.:..:...|     ...:|...|......||||      |:::.: :|..|...|.
Human   147 KESLGPDSSSGGQEDPA-----SQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDI- 205

  Fly   844 PPSWPPNHNFDNPVYGMQAETRLLPNNMRSKMNNFDQRSTMSTDYGD-DCNASGRVGSYSINYNH 907
              :|..:.         ||.||......|.|......::....|.|. .|..|.|.|:.:..|..
Human   206 --TWMKDD---------QALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKV 259

  Fly   908 DLLTKNLNADRTNPIV 923
            |::.:.    |:.|::
Human   260 DVIQRT----RSKPVL 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	27..92	CDD:284877
		EGF_CA	274..319	CDD:304395
		DSL	<479..518	CDD:302925
		DSL	<567..606	CDD:302925
FGFRL1	XP_024309860.1	I-set	56..139	CDD:254352	17/56 (30%)
		Ig2_FGFRL1-like	180..261	CDD:143264	21/92 (23%)
		Ig	284..378	CDD:325142
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900