DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drpr and NimC3

DIOPT Version :9

Sequence 1:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster
Sequence 2:	NP_524928.2	Gene:	NimC3 / 48772	FlyBaseID:	FBgn0001967	Length:	224	Species:	Drosophila melanogaster

Alignment Length:	265	Identity:	59/265 - (22%)
Similarity:	84/265 - (31%)	Gaps:	92/265 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLPVILIACLAQLVLAQADLKDLDGPNI----CKRR--ELYNVDVVYTELQSFQERGSTWCVTFP 59
            ||..:|...|. |||....|.::....|    |::.  ..|.|.|..|.:..          ..|
  Fly     1 MLQQVLYPMLV-LVLMTIHLVEVSSLAITNGHCQKNISVKYQVPVAKTRMAG----------AGP 54

  Fly    60 PRCSTYRIKHRVVNKTKTIAKNRI----VRDCCDGY-IASAGECVPHCSEPC-QHGRCISPEKCK 118
            |..|     |.:...:..:.:.|:    ::.||.|| ....|.|.|.|.|.| .|..|..|::|.
  Fly    55 PNAS-----HPIDLDSYVVYEERVRWDNIQVCCPGYRTILFGFCEPVCQEACPAHSYCAEPDRCH 114

  Fly   119 CDHGYGGPACDINCPPGWYGRNCSMQCDCLNNAVCEPFSGDCECAKGYTGAR--CADICPEGFFG 181
            |..||                              ||.....      ||.:  |..:|..|
  Fly   115 CQRGY------------------------------EPSHHHT------TGHQLICRPVCQGG--- 140

  Fly   182 ANCSEKCRCENGGKCHHVSGECQCAPGFTGP----LCDMRCPDGKHGAQCQQDCPCQNDGKCQPE 242
              |.|...|    ..|:   ||:|.|||...    ...:||          :...|.::.:..|.
  Fly   141 --CPEHSHC----VAHN---ECECWPGFKDASSWFSLSLRC----------ERVQCGHEQRFDPG 186

  Fly   243 TGACM 247
            ..||:
  Fly   187 RRACV 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	27..92	CDD:284877	15/75 (20%)
		EGF_CA	274..319	CDD:304395
		DSL	<479..518	CDD:302925
		DSL	<567..606	CDD:302925
NimC3	NP_524928.2	MSC	85..>212	CDD:286487	37/165 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810