DRSC/TRiP Functional Genomics Resources

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Protein Alignment drpr and KDR

DIOPT Version :9

Sequence 1:NP_001261276.1 Gene:drpr / 38218 FlyBaseID:FBgn0027594 Length:1042 Species:Drosophila melanogaster
Sequence 2:NP_002244.1 Gene:KDR / 3791 HGNCID:6307 Length:1356 Species:Homo sapiens


Alignment Length:134 Identity:31/134 - (23%)
Similarity:48/134 - (35%) Gaps:45/134 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   900 SYSINYNHDLL--------TKNLNADRTNPIVYNESLKEEHVYDEIKHKEGYKDPVKIYSK-ILF 955
            :::|...|.|.        |.|.....||||   ...|:.||...:.:.     |.:|..| ::.
Human   374 NHTIKAGHVLTIMEVSERDTGNYTVILTNPI---SKEKQSHVVSLVVYV-----PPQIGEKSLIS 430

  Fly   956 PEDEYDHLDYSRPSTSQ----------KPHYHRMNDAMLNIN---QDEEKPSNVKNMTVLLNKPL 1007
            |.|.|.:      .|:|          .||:         |:   |.||:.:|..:..|.:..|.
Human   431 PVDSYQY------GTTQTLTCTVYAIPPPHH---------IHWYWQLEEECANEPSQAVSVTNPY 480

  Fly  1008 PPTE 1011
            |..|
Human   481 PCEE 484

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drprNP_001261276.1 EMI 27..92 CDD:284877
EGF_CA 274..319 CDD:304395
DSL <479..518 CDD:302925
DSL <567..606 CDD:302925
KDRNP_002244.1 Ig 41..109 CDD:299845
IG_like 231..324 CDD:214653
Ig1_VEGFR 239..326 CDD:143270
IG_like 340..417 CDD:214653 12/45 (27%)
Ig2_VEGFR-2 348..417 CDD:143272 12/45 (27%)
Ig_2 551..661 CDD:290606
IG 565..661 CDD:214652
I-set 667..754 CDD:254352
IGc2 680..744 CDD:197706
PTKc_VEGFR2 826..1167 CDD:270681
Pkinase_Tyr 834..1160 CDD:285015
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1274..1318
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0200
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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