DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment drpr and Wsck

DIOPT Version :9

Sequence 1:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster
Sequence 2:	NP_733018.1	Gene:	Wsck / 318600	FlyBaseID:	FBgn0046685	Length:	791	Species:	Drosophila melanogaster

Alignment Length:	236	Identity:	46/236 - (19%)
Similarity:	83/236 - (35%)	Gaps:	55/236 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   770 VCRSGYTGDNCDELIASQRIADQS----ENSSRASVALTLVLMTLFACIIFAVFIYY-------- 822
            |.::.|:....|:.:.|  :.|.|    |....:.|||.:..:...:|::.::..|:
  Fly   370 VTKTMYSRGTHDQHVTS--LDDFSYATFEKGQSSVVALAVTCVIFGSCLLLSLIAYFYLRYKTCR 432

  Fly   823 RRRVS-------NLKTEIAHVH---YTHDTNPPSWPPNHNFDNPVYGMQAETRLLPNN-MRSKMN 876
            .||::       .|:|.|....   |..:.:|....| .||...:..:......:|.| :|..:|
  Fly   433 GRRLTGGNTHEMTLQTPIIERENNGYLVEDDPLPHSP-ENFKQQLQQLVEGYERIPRNALRLNVN 496

  Fly   877 NF--DQR-------STMSTDYGDDCNASGRVGSYSINYNHDLLTKNLNADRTNPIVYNESLKEEH 932
            :.  |.|       ...:.|:..||..            |.|...:||.     ....:.|:|..
  Fly   497 DVIGDGRFGEIITGKVSTNDFARDCTL------------HVLCLDDLNG-----TTQAQLLRELR 544

  Fly   933 VYDEIKHKEGYKDPVKIYSKILFPEDEYDHLDYSRPSTSQK 973
            ...::|.:|...|   .|.....|:..|...:..|.|..:|
  Fly   545 QLSQLKRQEHLLD---FYGVSASPDWFYLIFEQQRMSLKRK 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	27..92	CDD:284877
		EGF_CA	274..319	CDD:304395
		DSL	<479..518	CDD:302925
		DSL	<567..606	CDD:302925
Wsck	NP_733018.1	WSC	42..115	CDD:280068
		fn3	130..222	CDD:278470
		TyrKc	493..746	CDD:197581	21/110 (19%)
		PTKc	497..750	CDD:270623	20/106 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900