DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drpr and tek

DIOPT Version :9

Sequence 1:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster
Sequence 2:	XP_009299388.1	Gene:	tek / 30747	ZFINID:	ZDB-GENE-990415-56	Length:	1117	Species:	Danio rerio

Alignment Length:	184	Identity:	68/184 - (36%)
Similarity:	86/184 - (46%)	Gaps:	32/184 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 CPEGFFGANCSEKC-RCENGGKCHHVSGECQCAPGFTGPLCDMRCPDGKHGAQCQQDCPCQNDGK 238
            |..||:|.||:|.| ||.|||.|...:|||.|.|||.|..||:.|.:|:.||.|::.|.   ||.
Zfish   215 CRAGFWGPNCTESCPRCANGGVCDDTTGECVCPPGFRGHTCDIVCGEGRFGAGCKERCV---DGV 276

  Fly   239 CQP------ETGACMCNPGWTGDVCANKCPVGSYGPGCQESCECYKGAPCHHITGQCECPPGYRG 297
            |:.      :...|.|..||.|..|.:.||.|.||.||.:.|.|.||. |....| |.| .|..|
Zfish   277 CRALVFCLRDPYGCSCASGWRGLSCNDACPDGYYGAGCTQKCVCAKGR-CDRFRG-CVC-AGRHG 338

  Fly   298 ERCFD-----------ECQLNTYGFNCSMTCDCA-------NDAMCDRANGTCI 333
            .||.:           :.::|| |...|:.|..:       .|.....||.|.|
Zfish   339 SRCEEADSSPVISHLRDVEINT-GVELSVNCSASGRPAPLHGDITLITANRTTI 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	27..92	CDD:284877
		EGF_CA	274..319	CDD:304395	17/55 (31%)
		DSL	<479..518	CDD:302925
		DSL	<567..606	CDD:302925
tek	XP_009299388.1	Ig_Tie2_1	25..121	CDD:287411
		EGF_2	224..255	CDD:285248	17/30 (57%)
		IG_like	354..439	CDD:214653	10/39 (26%)
		fn3	541..621	CDD:278470
		FN3	633..717	CDD:214495
		PTKc_Tie2	809..1111	CDD:133219
		STYKc	817..1085	CDD:214568
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900