Protein Alignment drpr and Pear1

DIOPT Version :10

• Sequence 1: NP_001261276.1
• Gene: drpr / 38218
• FlyBaseID: FBgn0027594
• Length: 1042
• Species: Drosophila melanogaster
• Sequence 2: XP_063137697.1
• Gene: Pear1 / 295293
• RGDID: 1305653
• Length: 1068
• Species: Rattus norvegicus
• Alignment Length: 1108
• Identity: 360/1108 - (32%)
• Similarity: 488/1108 - (44%)
• Gaps: 153/1108 - (13%)

  Fly     1 MLPVILIACLAQLVLAQADLKDLDGPNICKRRELYNVDVVYTELQSFQERGSTWC---VTFPPRC 62
            :.|::|:|    |.|..|...:.:.||:|...|.:......:.|:.|....:..|   ...|..|
  Rat    38 LCPLLLLA----LGLRLAGTLNSNDPNVCTFWESFTTTTKESHLRPFSLPPAESCDRPWEDPHTC 98

  Fly    63 STYRIKHRVVNKTKTIAKNRIVRDCCDGYIASAGECVPHCSEPCQHGRCISPEKCKCDHGYGGPA 127
            :...:.:|.|.:......:|....||.||..|:|.|||.|::.|.||||::|.:|:|..|:.|..
  Rat    99 AQPTVVYRTVYRQVVKMDSRPRLQCCGGYYESSGACVPLCAQECVHGRCVAPNRCQCAPGWRGDD 163

  Fly   128 CDINCPPGWYGRNCSMQCDCLNNAVCEPFSGDCECAKGYTGARCADICPEGFFGANCSEKCRCEN 192
            |...|.||.:|..|...|.|.|::.|:|.||.|.|..|.....|...||:|.:|..|...|.| .
  Rat   164 CSSECAPGMWGPQCDRLCLCGNSSSCDPRSGVCFCPSGLQPPDCLQPCPDGHYGPACQFDCHC-Y 227

  Fly   193 GGKCHHVSGECQCAPGFTGPLCDMRCPDGKHGAQCQQDCPCQNDGKCQPETGACMCNPGWTGDVC 257
            |..|....|.|.|.||.|||.|::.|..|..|..|.:..||||.|..|...|:|.|.|||.|.:|
  Rat   228 GASCDPRDGACFCPPGRTGPSCNVPCSQGTDGFFCPRTYPCQNGGVPQGSQGSCSCPPGWMGVIC 292

  Fly   258 ANKCPVGSYGPGCQESCECYKGAPCHHITGQCECPPGYRGERCFDECQLNTYGFNCSMTCDCAND 322
            :..||.|.:||.|.:.|.|:.|..|...||||.|.|||.|:||.:||.:..:|.:|:.|||||..
  Rat   293 SLPCPEGFHGPNCTQECRCHNGGLCDRFTGQCHCAPGYIGDRCREECPVGRFGQDCAETCDCAPG 357

  Fly   323 AMCDRANGTCICNPGWTGAKCAERICEANKYGLDCNRTCECDMEHTDLCHPETGNCQCSIGWSSA 387
            |.|..|||.|:|..|:||.:|.||:|...:|||.|...|.||.||:..|||..|.|.|..||:..
  Rat   358 ARCFPANGACLCEHGFTGDRCTERLCPDGRYGLSCQDPCTCDPEHSLSCHPMHGECSCQPGWAGL 422

  Fly   388 QCTRPCTFLRYGPNCELTCNCKNGAKCSPVNGTCLCAPGWRGPTCEESCEPGTFGQDCALRCDCQ 452
            .|...|....:|..|:..|.|.:|..|...:|.|.||||:.||.|...|.|.|:|.:|:..|.|:
  Rat   423 HCNESCPQDTHGAGCQEHCLCLHGGVCLADSGLCRCAPGYTGPHCANLCPPNTYGINCSSHCSCE 487

  Fly   453 NGAKCEPETGQCLCTAGWKNIKCDRPCDLNHFGQDCAKVCDCHNNAACNPQNGSCTCAAGWTGER 517
            |...|.|..|.|:|..||:...|..||....:|..|...|.|.:...|:||.|:|||..||.|..
  Rat   488 NAIACSPVDGTCICKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEGVCSPQTGACTCTPGWRGVH 552

  Fly   518 CERKCDTGKFGHDCAQKCQCDFNNSLACDATNGRCVCKQDWGGVHCETNCRSGYYGENCDKVCRC 582
            |:..|..|:||..||..|.||  :|..||..:|.|.|:..|.|..|...|..|::|.||...|.|
  Rat   553 CQLPCPKGQFGEGCASVCDCD--HSDGCDPVHGHCRCQAGWMGTRCHLPCPEGFWGANCSNACTC 615

  Fly   583 LNNSSCDPDSGNCICSAGWTGADCAEPCPPGFYGMECKERCPEILHGNKSCDHITGEILCRTGYI 647
            .|..:|.|::|||:|:.|:.|..|..|||||.||..|
  Rat   616 KNGGTCVPENGNCVCAPGFRGPSCQRPCPPGRYGKRC---------------------------- 652

  Fly   648 GLTCEHPCPAGLYGPGCKLKCNCEHGGECNHVTGQCQCLPGWTGSNCNESCPTDTYGQGCAQRCR 712
                              :.|.|.:...|:...|.|.||.||||.:|:||||...:|..|:|.|:
  Rat   653 ------------------VPCKCNNHSSCHPSDGTCSCLAGWTGPDCSESCPPGHWGLKCSQPCQ 699

  Fly   713 CVHHKVCRKADGMCICETGWSGTRCDEVCPEGFYGEHCMNTCACPSANFQCHAAHG-CVCRSGYT 776
            |.|...|...||.|:|..|.:|..|.|.||...:|.:|...|.|.... .||...| |||..|::
  Rat   700 CHHGATCHPQDGSCVCIPGRTGPNCSEGCPSRMFGVNCSQLCQCDPGE-MCHPETGACVCPPGHS 763

  Fly   777 GDNCDELIASQR---IADQS---ENSSRASVALTLVLMTLFACIIFAVFIYYRRRVSNLKTEIAH 835
            |.:|.  :.||.   |...|   .||..|.:.:. ||.||...:: |:||.||......:.|...
  Rat   764 GAHCK--VGSQESFTIMPTSPVIHNSLGAVIGIA-VLGTLVVALV-ALFIGYRHWQKGKEHEHLA 824

  Fly   836 VHYT------HDTNPPSWPP--NHNFDNPVYG--MQAETRLLPNNM--------------RSKMN 876
            |.|:      .|...|...|  :|.:.||.|.  .|....|.|.|.              |...|
  Rat   825 VAYSTGRLDGSDYVMPDVSPSYSHYYSNPSYHTLSQCSPNLPPPNKIPGSQLFVSSQASERPNRN 889

  Fly   877 N-FDQRSTMSTDY-----GDDCNASGRVGSYSINYNHDLLTKNLNADRTNPIVYNE--------- 926
            : .|..:|:..|:     ..|...|.....||.:|.|          |..|..:..
  Rat   890 HGRDNHATLPADWKHRRESHDRGTSHLDRRYSCSYGH----------RNGPGPFCHKGPISEEGL 944

  Fly   927 -----SLKEEHVYDEIKHKEGYKDPVKIYSKILFPEDEYDHLDYSRPSTSQKP----HYHRMNDA 982
                 ||..|:.|..|:...|.....:          |..:::...|.:...|    |.......
  Rat   945 GASVMSLSSENPYATIRDLPGLPGEPR----------ESSYVEMKGPPSVSPPRQPLHLRDRQQQ 999

  Fly   983 MLNINQDE---EKPS-------NVKNMTVLLNKPLPPTEPEPQHECFDNTNT--NLDNVSTASPS 1035
            .|...:|.   |:|:       :|.:|     .||||..|...::...|::.  :.|......|.
  Rat  1000 QLQSQRDSGTYEQPTPLSRNEESVGSM-----PPLPPGLPPGHYDSPKNSHIPGHYDLPPVRHPP 1059

  Fly  1036 SSP 1038
            |.|
  Rat  1060 SPP 1062

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	26..92	CDD:462204	15/68 (22%)
		EGF_CA	274..319	CDD:473889	21/44 (48%)
		gliding_CglD	<451..579	CDD:468178	50/127 (39%)
		DSL	567..609	CDD:473190	17/41 (41%)
Pear1	XP_063137697.1	None