DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drpr and Scarf2

DIOPT Version :9

Sequence 1:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster
Sequence 2:	XP_038944006.1	Gene:	Scarf2 / 287949	RGDID:	1306013	Length:	838	Species:	Rattus norvegicus

Alignment Length:	479	Identity:	159/479 - (33%)
Similarity:	206/479 - (43%)	Gaps:	120/479 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 INCPPGW--YGRNCSMQ-CD----CLNNAVC-EPFSGDCECAKGYTGARCADICPEGFFGANCSE 186
            :.|..||  .|..|.:. |:    |..|.|| .|  |:|.|..||.||.|...||..|:|.:|.|
  Rat    54 LTCCAGWRQLGDECGIAVCEGNSTCSENEVCVRP--GECRCRHGYFGANCDTKCPRQFWGPDCKE 116

  Fly   187 KCRCENGGKCHHVSGECQCAPGFTGPLCDMRCPDGKHGAQCQQDCPCQNDGKCQPETGACMCNPG 251
            :|.|...|:|..|:|:|.|..             .:.||:|:..|.||: |.|.|.:|||.|.||
  Rat   117 RCSCHPHGQCEDVTGQCTCHA-------------RRWGARCEHACQCQH-GTCHPRSGACRCEPG 167

  Fly   252 WTGDVCANKCPVGSYGPGCQESCECYKGAPCHHITGQCECPPGYRGERCFDECQLNTYGFNCSMT 316
            |                                                        :|..|:..
  Rat   168 W--------------------------------------------------------WGAQCASA 176

  Fly   317 CDCANDAMCDRANGTCICNPGWTGAKCAERICEANKYGLDCNRTCECDMEHTDLCHPETGNCQCS 381
            |.|:..:.||...|.|:|:.||              :|..||..|.|   ::..|..::|.|||
  Rat   177 CYCSATSRCDPQTGACLCHAGW--------------WGRSCNNQCSC---NSSPCEQQSGRCQC- 223

  Fly   382 IGWSSAQCTRPCTFLRYGPNCELTCNCKNGAKCSPVNGTCLCAPGWRGPTCEESCEPGTFGQDCA 446
                     |..||   |..|:..|.|..| :|.||:|||.|.||:||..|.|.|..|.:|..|.
  Rat   224 ---------RERTF---GARCDRYCQCFRG-RCHPVDGTCACDPGYRGKYCREPCPAGFYGLGCR 275

  Fly   447 LRC-DCQNGAKCEPETGQCL-CTAGWKNIKCDRPCDLNHFGQDCAKVC-DCHNNAACNPQNGSCT 508
            .|| .|:....|....|:|| |..||...|||:||....:|:.|...| .|.:..|||...|.||
  Rat   276 RRCGQCKGQQPCTVVEGRCLTCEPGWNGTKCDQPCATGFYGEGCGHRCPPCRDGHACNHVTGKCT 340

  Fly   509 -CAAGWTGERCERKCDTGKFGHDCAQKC-QCDFNNSLACDATNGRCVCKQDWGGVHCETNCRSGY 571
             |.|||.|:|||.||..|.:|.|||..| .|   .|..||..:|||:|.....|.||...|.:|.
  Rat   341 HCNAGWIGDRCETKCSNGTYGEDCAFVCSDC---GSGHCDFQSGRCLCSPGVHGPHCNVTCPAGL 402

  Fly   572 YGENCDKVCRCLNNSSCDPDSGNC 595
            :|.:|.:.|.| :..||||.:|.|
  Rat   403 HGVDCAQACSC-HEESCDPVTGAC 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	27..92	CDD:284877
		EGF_CA	274..319	CDD:304395	3/44 (7%)
		DSL	<479..518	CDD:302925	16/40 (40%)
		DSL	<567..606	CDD:302925	12/29 (41%)
Scarf2	XP_038944006.1	exchanger_TraA	<74..431	CDD:411343	153/459 (33%)
Scarf2	XP_038944006.1	PHA03247	<683..837	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810