Protein Alignment drpr and STAB1

DIOPT Version :9

• Sequence 1: NP_001261276.1
• Gene: drpr / 38218
• FlyBaseID: FBgn0027594
• Length: 1042
• Species: Drosophila melanogaster
• Sequence 2: XP_016861487.1
• Gene: STAB1 / 23166
• HGNCID: 18628
• Length: 2615
• Species: Homo sapiens
• Alignment Length: 1181
• Identity: 256/1181 - (21%)
• Similarity: 338/1181 - (28%)
• Gaps: 510/1181 - (43%)

  Fly    65 YRI-KHRVVNKTKTIAKNRI---------VRDCCDGYIASAGECVP------------------- 100
            |.| .|..:...|.|:|.||         |....:|.|....|.||
Human   576 YHIYNHGQLTVEKLISKGRILTMANQVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGI 640

  Fly   101 ------------HCSEPCQH----GRCISPEKCKCDHGYGGPACDINCPPGWYGRNCSMQCDCLN 149
                        ||||. ||    |.|:                               .|..||
Human   641 LLPPTILPILPKHCSEE-QHKIVAGSCV-------------------------------DCQALN 673

  Fly   150 NAVCEP-------FSGDCECAKGYTGAR-----CADICPE---------GFFGANCSEKC----- 188
            .:.|.|       |..:|......||..     ||..|.:         ||||.:|:: |
Human   674 TSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCKGFFGPDCTQ-CPGGFS 737

  Fly   189 -RCENGGKCH---HVSGECQCAPGFTGPLCDMRCPDGKHGAQCQQDCPCQNDGKCQPETGA---C 246
             .|...|.|.   ..:|.|.|.|.:.|..|.:.....|||.|||:||.|.: |.|....|:   |
Human   738 NPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVH-GLCDNRPGSGGVC 801

  Fly   247 M---CNPGWTGDVCANKCPVGSYGP-GCQESCECYKGAPCHHITGQCECPPGYRGERCFDECQLN 307
            .   |.||::|..|...  :|..|| |..:.|..:..........:|.|..|:.|:
Human   802 QQGTCAPGFSGRFCNES--MGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGD--------- 855

  Fly   308 TYGFNC--SMTCD------CANDAMCDRAN-GT--CICNPGWTGAKCAERICEANKYGLDCNRTC 361
              ||:|  |..|.      |:.:|.|...: ||  |.|:.||:|   ..|:|.|    :|   .|
Human   856 --GFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSG---DGRVCVA----ID---EC 908

  Fly   362 ECDME---HTD-LCH---PETGNCQCSIGWS--SAQCT--RPCTFLRYGPNCELTCNCKNGAKCS 415
            |.||.   ||| ||.   |....|.|.:|::  ..||:  .||   |.|..     .|...|.|.
Human   909 ELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPC---RAGNG-----GCHGLATCR 965

  Fly   416 PVNG---TCLCAPGWRGP--TC--------EESCEPGTFGQ------------------------ 443
            .|.|   .|.|.||:.|.  :|        |.:.....|.|
Human   966 AVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRRVTALVPSEAA 1030

  Fly   444 -------DCA-----------LRCDCQNGAKCEPET----GQCLCTAG--------------W-K 471
                   |.|           :|.....||..|.|.    ||.:.|..              | :
Human  1031 VRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPTTRWEIRNISGRVWVQ 1095

  Fly   472 NIKCDRPCDL------NHF--------------GQDCAKVCDC------------HNNAACNPQN 504
            |...| ..||      .|.              ||...:..|.            |:...  ||
Human  1096 NASVD-VADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPAFSLFRELLQHHGLV--PQ- 1156

  Fly   505 GSCTCAAGWT------------GERCERKCDT----------------GKFGHDCAQKCQCDFNN 541
              ...|..:|            |.......||                .|.||          .|
Human  1157 --IEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSMETLRKGGH----------RN 1209

  Fly   542 SLACDA--------------------------------------TNGRCVCKQDWGGVHCET--- 565
            ||...|                                      |.|...|...    |.|.
Human  1210 SLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRCLHS----HAEALRE 1270

  Fly   566 NCRSGYYGENCDKVCRCLNNSSC-DPDSGNCICSAGWT-----GADCAE-----PCPPGFYGMEC 619
            .|      .||.:..||...... |....:|:..:|::     ...||:     .|.|||:|..|
Human  1271 KC------VNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFFGTLC 1329

  Fly   620 KERCP----EILHGNKSC-DHI--TGEILCRTGYIGLTCEHPCPAGLYGPGCKLKCNCEHG---- 673
             |.||    .:..|:..| |..  :||..|..|:.|..|| .|..|.|||.|...|:|.||
Human  1330 -EPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACE-VCELGRYGPNCTGVCDCAHGLCQE 1392

  Fly   674 ---GECNHVTGQCQCLPGWTGSNCNESCPTDTYGQGCAQRCRCVHHKVCRKADGMCICETGWSGT 735
               |:     |.|.|..||.|..|::...:....:.|.....||....   ....|.|..|:||.
Human  1393 GLQGD-----GSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSA---GASTCACAAGYSGN 1449

  Fly   736 R--CDEV---------------------------CPEGFY--GEHCMNTCACPSANFQCHAAHGC 769
            .  |.||                           |.:|:.  ||.|....:|...:..||....|
Human  1450 GIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAEC 1514

  Fly   770 V----------CRSGYTGD----------------NCDELIASQRIADQSEN------------- 795
            :          ||.||:||                .|......:...|....
Human  1515 IPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGDGL 1579

  Fly   796 SSRASVALTLV--------------------LMTLFACII--------------FAVFIYYRRRV 826
            :.||.|.|.|:                    |:...:|..              |.:|:.:...:
Human  1580 TCRARVGLELLRDKHASFFSLRLLEIHGRLRLLPFHSCCCCLPQEYKELKGDGPFTIFVPHADLM 1644

  Fly   827 SNL-KTEIAHV 836
            ||| :.|:|.:
Human  1645 SNLSQDELARI 1655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	27..92	CDD:284877	10/36 (28%)
		EGF_CA	274..319	CDD:304395	10/52 (19%)
		DSL	<479..518	CDD:302925	12/82 (15%)
		DSL	<567..606	CDD:302925	8/44 (18%)
STAB1	XP_016861487.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900