DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drpr and old-2

DIOPT Version :9

Sequence 1:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster
Sequence 2:	NP_496123.1	Gene:	old-2 / 191738	WormBaseID:	WBGene00003863	Length:	498	Species:	Caenorhabditis elegans

Alignment Length:	227	Identity:	46/227 - (20%)
Similarity:	83/227 - (36%)	Gaps:	54/227 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   759 ANFQCHAAHGCVCRSGYTGDNCDELIASQRIADQSENS----SRASVALTLVLMTLF-------A 812
            |.|..:....|..|:...|.|.::  :.:|:...||.:    |.....:.:.|.::|       .
Worm     9 ALFSSYCFASCYARNLTLGRNFED--SFKRVPRASEKNELGDSNVQQIIFISLYSVFVALAIGIC 71

  Fly   813 CIIFAVFIYYRRRVSNLK----------TEIAHVHYTHDTNPPS---WPPNHNFDNPVYG----- 859
            |:|.|.....|:..:|..          |......|:::..||.   :|.....|:  :|
Worm    72 CLIKAYKSKKRQLPANRSKGNEYLLEPTTADQKKRYSNNIVPPEPTPYPITSGEDD--FGKTPSR 134

  Fly   860 -----MQAETRLLPNNMRSKMNNFDQRSTMSTDYGDDCNAS-GR---VGSYSINYNHDLLTKNLN 915
                 ...|.:|.|.|.|.|..::.....::.   :|.:.| ||   .|.:.|.....|.:||..
Worm   135 LSNEECPPELKLAPINDRIKYLHYYAEVEINE---EDLDISKGRPLGSGEFGIIRKGFLRSKNSK 196

  Fly   916 ADRT---------NPIVYNESLKEEHVYDEIK 938
            ...|         :|:.....:::|.:|||:|
Worm   197 NKETESRLEVAVKSPLNEYNHIQQELIYDELK 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	27..92	CDD:284877
		EGF_CA	274..319	CDD:304395
		DSL	<479..518	CDD:302925
		DSL	<567..606	CDD:302925
old-2	NP_496123.1	PTKc	175..458	CDD:270623	13/54 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900