DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drpr and ver-4

DIOPT Version :9

Sequence 1:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster
Sequence 2:	NP_509835.2	Gene:	ver-4 / 186632	WormBaseID:	WBGene00006897	Length:	1216	Species:	Caenorhabditis elegans

Alignment Length:	257	Identity:	50/257 - (19%)
Similarity:	70/257 - (27%)	Gaps:	107/257 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   466 CTAGWKNIKCDRPCDLNHFGQDCAKVCDCHNNAACNPQNGSCTCAAG-----WTGERCERKCDTG 525
            |....||:|.:.|....|.|               .|:.|..|.|..     |...:..|:||||
Worm    54 CYGQHKNLKIEPPKREEHAG---------------FPEIGIRTSAEWKKNEYWFLLKNVRQCDTG 103

  Fly   526 KFGHDCAQKCQCD-FNNSLACDAT--------------------NGRCV---CKQ----DWGGVH 562
            .:      .|..| |..|:..:..                    ||..:   ||.    |...|.
Worm   104 SY------YCVSDEFKESMLQNTVHIFVRKLDIFVPLKTIYHEHNGSEIIIPCKTTKFVDTKNVE 162

  Fly   563 CETN------CRSGY---YGENCDK-------------VCRCLNN---------SSCDPDS---- 592
            ...|      ...||   ||....|             .|:..|:         |:.|||:
Worm   163 LYVNQVKLNSALQGYDQRYGFKLTKNMYTMKPNSTVFFECKYTNDSNQDLDYYISNSDPDATLID 227

  Fly   593 ---------------GN---CICSAGWTGADCAEPCPPGFYGMECKERCPEILHGNKSCDHI 636
                           ||   ..|...:.|:|...|.......:||.:...:..:.|:|...|
Worm   228 QYFFYWEKSNDVPYVGNNYSITCHLVYIGSDSLRPLNHQEIVLECPQNQCDGGYNNQSAHEI 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	27..92	CDD:284877
		EGF_CA	274..319	CDD:304395
		DSL	<479..518	CDD:302925	7/43 (16%)
		DSL	<567..606	CDD:302925	15/85 (18%)
ver-4	NP_509835.2	ig	609..679	CDD:278476
		IG_like	611..692	CDD:214653
		IG_like	709..782	CDD:214653
		IGc2	714..772	CDD:197706
		STYKc	870..1175	CDD:214568
		PTKc	874..1176	CDD:270623
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900