DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drpr and C53B7.2

DIOPT Version :9

Sequence 1:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster
Sequence 2:	NP_509154.2	Gene:	C53B7.2 / 183744	WormBaseID:	WBGene00016893	Length:	169	Species:	Caenorhabditis elegans

Alignment Length:	193	Identity:	39/193 - (20%)
Similarity:	56/193 - (29%)	Gaps:	79/193 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   597 CSAGWTGADCAEPCPPGFYGMECKERCPEILHGNKSCDHITGEILCRTGYIGLTCEHPCPAGLYG 661
            |......:.|.:.|||                                     |||.|      .
Worm    29 CGINEQYSPCTQMCPP-------------------------------------TCESP------N 50

  Fly   662 PGCKLKCNCEHGGECNHVTGQCQCLPGWTGSNCNESCPTDTYGQGCAQRCRCVHHKVCRKADGMC 726
            |.|::.|          ....|.||||...||..:..|.::..|  .|..||..:..||  .||
Worm    51 PQCRVDC----------TRPSCTCLPGHVYSNSRQCIPANSCYQ--TQSLRCRMNNDCR--PGM- 100

  Fly   727 ICETGWSGTRCDEVCPEGFYGEHCMNTCACPSANF-----------QC----HAAHGCVCRSG 774
            .|..|:.|      ...|.|....:::.:..|::.           :|    |..|..:|..|
Worm   101 YCINGYCG------AASGVYTRTVVSSSSLSSSSSGHRHHSHRSQGECSLDVHCDHRKICIDG 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	27..92	CDD:284877
		EGF_CA	274..319	CDD:304395
		DSL	<479..518	CDD:302925
		DSL	<567..606	CDD:302925	1/8 (13%)
C53B7.2	NP_509154.2	TIL	29..82	CDD:366828	20/105 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900