DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drpr and igcm-4

DIOPT Version :9

Sequence 1:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster
Sequence 2:	NP_508377.1	Gene:	igcm-4 / 180518	WormBaseID:	WBGene00022418	Length:	541	Species:	Caenorhabditis elegans

Alignment Length:	161	Identity:	34/161 - (21%)
Similarity:	57/161 - (35%)	Gaps:	17/161 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   801 VALTLVLMTLFACIIFAVFIYYRRRVSNLKTEIAHVHYTHDTNPPSWP-------PNHNFDNPVY 858
            :.|..|::|||..::....|:.::...:...:        |..||..|       |..|..:...
Worm   389 LVLLAVVVTLFIFVVILAIIWLKKNQESTSGK--------DLKPPPPPRMPPPAAPQDNDWSSDR 445

  Fly   859 GMQAETRLLPNNMRSKMNNFDQRSTMSTDYGDDCNASGRVGSYSINYNHDLLTKNLNADRTNPIV 923
            .:.:...||.:|...|..|..:....:.|..:...|..|....|..|::..|.......|.|..:
Worm   446 TLHSSKPLLLHNSMFKHTNPIKFHAATMDRKNMIRAERRFDEVSNVYDNSTLQPYHIQQRNNNSI 510

  Fly   924 YNESLKEEHVYDEIKH--KEGYKDPVKIYSK 952
            ||...:...||:...:  .|.|.|....|.|
Worm   511 YNGGYRTLEVYNHRNYPTSEEYTDQDMFYYK 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
drpr	NP_001261276.1	EMI	27..92	CDD:284877
		EGF_CA	274..319	CDD:304395
		DSL	<479..518	CDD:302925
		DSL	<567..606	CDD:302925
igcm-4	NP_508377.1	IGc2	52..114	CDD:197706
		I-set	159..235	CDD:254352
		IGc2	166..225	CDD:197706
		IG_like	261..373	CDD:214653
		Ig	269..374	CDD:299845
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900