DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drpr and T25F10.3

DIOPT Version :9

Sequence 1:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster
Sequence 2:	NP_504708.1	Gene:	T25F10.3 / 179067	WormBaseID:	WBGene00020806	Length:	429	Species:	Caenorhabditis elegans

Alignment Length:	261	Identity:	62/261 - (23%)
Similarity:	78/261 - (29%)	Gaps:	88/261 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   325 CDRANGTCICNP----GWTGAKCAERICEANKYGLDCNRTCECDMEHTDLCHPETGNCQCSIGWS 385
            |.|.......||    .||..        |:.|.:|....   ..|..|.|....|....
Worm    63 CCRRGSPVAENPQLVSNWTET--------ASDYAVDEKLV---GTEQDDHCRVFQGTFLL----- 111

  Fly   386 SAQCTRPCTFLRYGPNCELTCNCKNGAKCSPVNGTCLCAPGWRGPTCEESCEPGTFGQDCALRCD 450
            ||......||:.||..|          ||               |..|:.    ...|.|.....
Worm   112 SAAALYNSTFVSYGVQC----------KC---------------PDAEQQ----QLDQHCRQLPA 147

  Fly   451 CQNGAKCEPETGQCLCTAGWKNIKCDRPCDLNHFGQDCAKVCDCHNNAACNPQNGSCTCAAGWTG 515
            ||||.......|        :...|.:|    :||:.|.|:||.....|....|..|:|...:.|
Worm   148 CQNGGYRSQSIG--------RRCSCPQP----YFGEYCEKLCDQGQVLAGIDGNNYCSCLPFYQG 200

  Fly   516 ERC-ERKCDTGKFGHDCAQKCQCDFNNSLACDATNGRCVCKQDWGGVHCE-------TNCRSGYY 572
            |.| :..|..|  ||:                 ..|||.|..::.|.|||       :|.|...|
Worm   201 ETCSDLVCLNG--GHE-----------------FRGRCSCPHNFVGYHCEIDTNKTKSNSRYTKY 246

  Fly   573 G 573
            |
Worm   247 G 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	27..92	CDD:284877
		EGF_CA	274..319	CDD:304395
		DSL	<479..518	CDD:302925	12/38 (32%)
		DSL	<567..606	CDD:302925	3/7 (43%)
T25F10.3	NP_504708.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24035
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010