DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment drpr and F56B3.2

DIOPT Version :9

Sequence 1:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster
Sequence 2:	NP_499983.2	Gene:	F56B3.2 / 176902	WormBaseID:	WBGene00018928	Length:	432	Species:	Caenorhabditis elegans

Alignment Length:	427	Identity:	96/427 - (22%)
Similarity:	142/427 - (33%)	Gaps:	146/427 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   402 CELTCNCKN-GAKCSPVNGTCLCAPGW--------RGPTCEESCEPGTFGQDCALRCD----CQN 453
            |::..:|:| |:.|  :.|.|.|.|.:        |.|.|...  |...|..|:.:|.    |:|
Worm    38 CDINGDCENKGSIC--LRGKCRCHPHYTETRDEKGRLPKCAPL--PAKIGARCSSKCREPLFCRN 98

  Fly   454 GAKCE--------PETGQCLCTAGWKNIKCDRPCDLNHFGQDCAKVCDCHNN-AACNPQNGSCTC 509
            | :|:        ...|:|:.|              :..|..|::..||.:. :||  .|..|.|
Worm    99 G-ECQCVQRGTTRVSNGECITT--------------SRVGDRCSRHYDCTSPFSAC--VNSQCVC 146

  Fly   510 AAG--WTGERC--ERKCDTGKF-GHDCAQKCQCDFNNSLACDATNGRCVCKQDWGGVHCETNCRS 569
            ..|  ..|.||  ...|..||. |..|.:|.    :.|||.:..:.:..|..   |..|.|...|
Worm   147 ITGTIQMGSRCVAAANCPFGKLPGQSCVRKS----DPSLAFNIPSNQDNCPM---GQVCITAGES 204

  Fly   570 GYYGENCDKVCRCLNNS-----SCDPDSGNCICSAGWTGADCAEPCPPGFYGMECKERCPEILHG 629
             ..|..|..:|. ||.:     |||||:...:                         :||...|
Worm   205 -QVGHCCPVICP-LNTTTDTRYSCDPDAAPAL-------------------------KCPSDSH- 241

  Fly   630 NKSC----DHITGEILCRTGYIGLTCEHPC---------------PAGLYGPGCKLKCNCEHGGE 675
              .|    |....:..|        |..||               |.|.....|.....|..|..
Worm   242 --YCYFLSDGSFSQAAC--------CRRPCNAMAPNALYVDYHCMPRGQLNSACTSNAQCGGGEG 296

  Fly   676 CNHVTGQCQCLPGWTGS---------NCNESCPTDTYGQGCAQRCRCVHHKVCRKA---DGMCIC 728
            ...:.|||||...:..:         |.::||..|...:..::...|:      ||   :.:|..
Worm   297 MECMKGQCQCQQNFHPAVDVLTNPLKNPSQSCSRDCESENLSKDTSCM------KAVPLNSLCFI 355

  Fly   729 ETGWSGTRCDEVCPE--GFYGEHCMNTCACPSANFQC 763
            :         :.||:  |.|...||..|...:.|.:|
Worm   356 Q---------KQCPQNSGCYRGRCMCRCGFAAKNGKC 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	27..92	CDD:284877
		EGF_CA	274..319	CDD:304395
		DSL	<479..518	CDD:302925	11/41 (27%)
		DSL	<567..606	CDD:302925	11/43 (26%)
F56B3.2	NP_499983.2	EB	111..157	CDD:279949	14/61 (23%)
		EB	266..312	CDD:279949	10/45 (22%)
		EB	332..383	CDD:279949	12/65 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900