Protein Alignment drpr and pqn-25

DIOPT Version :10

• Sequence 1: NP_001261276.1
• Gene: drpr / 38218
• FlyBaseID: FBgn0027594
• Length: 1042
• Species: Drosophila melanogaster
• Sequence 2: NP_741140.1
• Gene: pqn-25 / 175759
• WormBaseID: WBGene00004114
• Length: 672
• Species: Caenorhabditis elegans
• Alignment Length: 764
• Identity: 173/764 - (22%)
• Similarity: 241/764 - (31%)
• Gaps: 269/764 - (35%)

  Fly   132 CPPG----WYGRN------CSMQ--CDCLNNAVCEPFSGDCECAKGY--------TGARCADICP 176
            ||||    :...|      |:.|  |.|.:::....|...|:.|..|        |..:|
 Worm    50 CPPGLTPLFSNSNFNQPLTCTPQDACSCYSSSGSSRFGTICQYASTYNNYICCYSTNTQC----- 109

  Fly   177 EGFFGANCSEKCRCENGGKCHHVSGECQCAPGFTGPLCDMRCPDGKHGAQCQQDCPCQNDGKCQP 241
                |:|.|.:...  .|:....|...|||.|:|       |.:|    .|   ||..|...|..
 Worm   110 ----GSNSSPQVSA--SGQVVTCSTNTQCASGYT-------CNNG----AC---CPNTNSNTCSS 154

  Fly   242 E-TGACMCNPGWTGDVCANKCPVGSYGPGCQESCECYKGAPCHHITGQCECPPGY--RGERCFD- 302
            . ...|:.........|.|...:||   .||.:.:|..|:.|.:  ..|:|..||  ..::|..
 Worm   155 NGNNGCLAGQTMVNGQCYNSVNIGS---ACQSTQQCLGGSQCQN--NICQCYSGYVNVNQQCVIS 214

  Fly   303 ---ECQLNTY------------GFNCSMTCDCANDAMCDRANGTCICNPGWTGAKCAERICEANK 352
               .|||.|.            |.||..:..|.::::|  .|..|.||               |.
 Worm   215 NGLNCQLGTVSYNSQCITLASPGQNCQTSSQCIDNSVC--MNQMCTCN---------------NN 262

  Fly   353 YGLDCNRTCECDMEHTDLCHPETGNCQCSIGWSSAQCTRPCTFLRYGPNCELTCNCKNGAKCSPV 417
            |.|...           .|.|.|          |:.|.:..|.                     |
 Worm   263 YRLVYG-----------YCVPIT----------SSICQQTQTL---------------------V 285

  Fly   418 NGTCLCAPGWRGPTCEESCEPGTFGQDCALRCDCQNGAKCEPETGQCLCTAGWKNIKCDRPCDLN 482
            |..|:..              ...|:.|.....|..||.|  .:|.|.||.|...:
 Worm   286 NNQCVLL--------------SIVGETCIANQQCVGGAMC--NSGTCQCTNGATAM--------- 325

  Fly   483 HFGQDCAKVCDCHNNAACNPQ----NGSCTCAAGWTGERCERKCDTGKFGHDCAQKCQCDFNNSL 543
             :|     .|...::::||..    ||.|              .:|.:.|..|:...|| .||::
 Worm   326 -YG-----YCISSSSSSCNSNQVSINGMC--------------YNTVQVGGSCSFSQQC-LNNAV 369

  Fly   544 ACDATNGRCVCKQDWGGVHCETN--CRSGY------YGENCDKVCRCLNNSSCDPDSGNCICSAG 600
               .||.  :|...:..|.|.||  |.|..      .|..|....:||:||.|.    :.||.
 Worm   370 ---CTNN--ICVSTFCSVSCSTNQVCISNQCYNYVSIGSQCVGSQQCLSNSQCI----SSICQ-- 423

  Fly   601 WTGADCAEPCPPGFYGMECKERCPEILHGNKSCDHITGEIL----C-RTGYIGLTCEHP--CPAG 658
                     ||.|  ..:....|....:.|..|.  ..::|    | .|..||..|:.|  |
 Worm   424 ---------CPQG--TQQSNGVCTGNNNNNNQCQ--PNQVLINNQCYNTVSIGFQCQFPQQC--- 472

  Fly   659 LYGPGC-KLKCNCEHGGECNHVTGQCQCLPGWTGSNCNES-------C-PTDTYGQGCAQRCRCV 714
            |....| ...|.|..|.  .:|.|.||   |.:...||.:       | .|.:.|..|....:|:
 Worm   473 LGNSQCMNSMCQCPTGS--TNVNGYCQ---GGSNGQCNSNQVLINNQCYNTVSIGFQCQFAQQCL 532

  Fly   715 HHKVCRKADGMCICETGWSGTRCDEVCPEG----------FYGEHCMNTCACPS---------AN 760
            .:..|  .:.:|.|.:|.|..  :..|..|          :|...|.||....|         .|
 Worm   533 GNSQC--LNSICQCPSGSSNV--NGYCQGGSNGQCNSNQVYYNNQCYNTVPIGSQCQITQQCLGN 593

  Fly   761 FQCHAAHGCVCRSGYTGDN--CDELIASQRIADQSENSSRASVALTLVL 807
            .||..:. |.|.||.|..|  |         ...|.:|:..|...|:.|
 Worm   594 SQCMNSF-CQCPSGTTNVNNFC---------TTSSSSSNLCSAGQTVQL 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	26..92	CDD:462204
		EGF_CA	274..319	CDD:473889	15/62 (24%)
		gliding_CglD	<451..579	CDD:468178	34/139 (24%)
		DSL	567..609	CDD:473190	11/47 (23%)
pqn-25	NP_741140.1	EB	160..211	CDD:460294	14/55 (25%)
		EB	219..270	CDD:460294	16/78 (21%)
		EB	278..329	CDD:460294	17/102 (17%)
		EB	341..>376	CDD:460294	12/54 (22%)
		EB	384..435	CDD:460294	17/67 (25%)
		EB	450..496	CDD:460294	15/50 (30%)
		EB	504..555	CDD:460294	12/54 (22%)
		EB	563..614	CDD:460294	14/51 (27%)