DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drpr and CCBE1

DIOPT Version :9

Sequence 1:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster
Sequence 2:	XP_016881045.1	Gene:	CCBE1 / 147372	HGNCID:	29426	Length:	435	Species:	Homo sapiens

Alignment Length:	215	Identity:	48/215 - (22%)
Similarity:	72/215 - (33%)	Gaps:	80/215 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 GSTWCVTFPPR------CSTYRI---KHRVVNKTKTIAKNRIVRDCCDGYIASAGECVPH----C 102
            |.||.....|.      ||..:|   |:..:..:..:. ....:.||.||....|:|:|.    |
Human    30 GHTWTYREEPEDGDREICSESKIATTKYPCLKSSGELT-TCYRKKCCKGYKFVLGQCIPEDYDVC 93

  Fly   103 SE-PCQHGRCISPEKCKCDHGYGGPACDINCPPGW-YGRNCSMQCDCLNNAVCEPFSGDCECAKG 165
            :| ||:.         :|...:|...|  .|.||: |.|....:.:       :|:
Human    94 AEAPCEQ---------QCTDNFGRVLC--TCYPGYRYDRERHRKRE-------KPY--------- 131

  Fly   166 YTGARCADICPEGFFGANCSEKCRCENGGKCHHV------SGECQCAPGFTGPLCDMRCPDGKHG 224
                 |.||           ::|...||..|.|:      |..|:|..|:      :|..|||
Human   132 -----CLDI-----------DECASSNGTLCAHICINTLGSYRCECREGY------IREDDGK-- 172

  Fly   225 AQCQQDCPCQNDGKCQPETG 244
                   .|....|...:||
Human   173 -------TCTRGDKYPNDTG 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	27..92	CDD:284877	11/49 (22%)
		EGF_CA	274..319	CDD:304395
		DSL	<479..518	CDD:302925
		DSL	<567..606	CDD:302925
CCBE1	XP_016881045.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900